Irradiation Induces WAF1 Expression through a p53-independent Pathway in KG-1 Cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

Radiobiology for the Radiologist.

1974 • 3,582 citations

p21 is a universal inhibitor of cyclin kinases

1993 • 3,408 citations

The Biology of Oxygen Radicals

1978 • 3,361 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

Checkpoints: Controls That Ensure the Order of Cell Cycle Events

1989 • 3,036 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

1994 • 2,025 citations

Definition of a consensus binding site for p53

1992 • 2,000 citations

Mammalian G1 cyclins

1993 • 1,990 citations

p53 function and dysfunction

1992 • 1,918 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

Oxygen Radicals and Human Disease

1987 • 1,854 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest

1994 • 1,475 citations

Cloning of Senescent Cell-Derived Inhibitors of DNA Synthesis Using an Expression Screen

1994 • 1,368 citations

mdm2 expression is induced by wild type p53 activity.

1993 • 1,286 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

Identification of p53 as a Sequence-Specific DNA-Binding Protein

1991 • 1,109 citations

Cell Proliferation in Carcinogenesis

1990 • 1,063 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

p53 mutations in colorectal cancer.

1990 • 1,030 citations

Oncogenic forms of p53 inhibit p53-regulated gene expression

1992 • 933 citations

Radiobiology for the Radiologist

1988 • 807 citations

Radiosensitivity in ataxia-telangiectasia: a new explanation.

1980 • 784 citations

p53 functions as a cell cycle control protein in osteosarcomas.

1990 • 774 citations

Induction of WAF1/CIP1 by a p53-independent pathway.

1994 • 773 citations

A transcriptionally active DNA-binding site for human p53 protein complexes.

1992 • 729 citations

Wild-type p53 activates transcription in vitro

1992 • 609 citations

Extreme instability of myc mRNA in normal and transformed human cells.

1984 • 522 citations

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.

1989 • 473 citations

Abnormal structure and expression of p53 gene in human hepatocellular carcinoma.

1990 • 413 citations

Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.

1991 • 410 citations

Human actin genes are single copy for alpha-skeletal and alpha-cardiac actin but multicopy for beta- and gamma-cytoskeletal genes: 3' untranslated regions are isotype specific but are conserved in evolution.

1983 • 393 citations

Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate.

1985 • 387 citations

Braking the cycle

1993 • 378 citations

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

1990 • 364 citations

Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin‐1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation

1993 • 351 citations

Growth factor-stimulated protein phosphorylation in 3T3-L1 cells. Evidence for protein kinase C-dependent and -independent pathways.

1985 • 351 citations

Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression

1992 • 333 citations

Frequent Mutations in the p53 Tumor Suppressor Gene in Human Leukemia T-Cell Lines

1990 • 296 citations

Monoclonal antibody analysis of p53 expression in normal and transformed cells

1986 • 285 citations

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

1991 • 277 citations

p53 in hematologic malignancies

1994 • 269 citations

Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones.

1986 • 263 citations

Activation of human immunodeficiency virus type 1 by DNA damage in human cells

1988 • 256 citations

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage.

1990 • 223 citations

Identification of a ZP3-binding protein on acrosome-intact mouse sperm by photoaffinity crosslinking.

1990 • 219 citations

p53 in hematologic malignancies

1994 • 206 citations

Effects of irradiation on the release of growth factors from cultured bovine, porcine, and human endothelial cells.

1989 • 197 citations

Frequent mutations in the p53 gene in human myeloid leukemia cell lines

1992 • 197 citations

Levels of p53 protein increase with maturation in human hematopoietic cells.

1991 • 191 citations

Modulation of gene expression in Syrian hamster embryo cells following ionizing radiation.

1990 • 187 citations

A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.

1991 • 184 citations

Cell Kinetics and Radiation Biology

1986 • 179 citations

Free radical‐induced pathology

1985 • 150 citations

Ionizing radiation induces expression of interleukin 6 by human fibroblasts involving activation of nuclear factor-kappa B.

1993 • 150 citations

Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.

1991 • 148 citations

Mutational inactivation of the p53 gene in the human erythroid leukemic K562 cell line

1993 • 147 citations

Effects of c-myc Expression on Cell Cycle Progression

1994 • 141 citations

How p53 Suppresses Cell Growth

1993 • 140 citations

Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.

1991 • 138 citations

The action of caffeine on X-irradiated HeLa cells. I. Delayed inhibition of DNA synthesis.

1977 • 124 citations

Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines.

1992 • 117 citations

Superoxide dismutase amplifies organismal sensitivity to ionizing radiation

1989 • 116 citations

Increased expression of p53 protein in human leukemia cells.

1986 • 94 citations

The Action of Caffeine on X-Irradiated HeLa Cells. I. Delayed Inhibition of DNA Synthesis

1977 • 91 citations

In vivo activation by ultraviolet rays of the human immunodeficiency virus type 1 long terminal repeat.

1990 • 75 citations

Alternative splicing of the p53 tumor suppressor gene in the Molt-4 T-lymphoblastic leukemia cell line

1993 • 60 citations

Induction of transcription from the long terminal repeat of Moloney murine sarcoma provirus by UV-irradiation, x-irradiation, and phorbol ester.

1990 • 50 citations

Lymphotoxin: stimulation and regulation of colony-stimulating factors in fibroblasts

1989 • 39 citations

Transcription and Translation

2021 • 34 citations

Lymphotoxin: stimulation and regulation of colony-stimulating factors in fibroblasts

1989 • 29 citations

Irradiation increases levels of GM-CSF through RNA stabilization which requires an AU-rich region in cancer cells

1992 • 29 citations

Irradiation Increases Expression of GM-CSF in Human Fibroblasts by Transcriptional and Post-transcriptional Regulation

1994 • 17 citations