Lymphotoxin: stimulation and regulation of colony-stimulating factors in fibroblasts

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.

1982 • 618 citations

Recombinant human TNF induces production of granulocyte–monocyte colony-stimulating factor

1986 • 528 citations

Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.

1986 • 396 citations

Human actin genes are single copy for alpha-skeletal and alpha-cardiac actin but multicopy for beta- and gamma-cytoskeletal genes: 3' untranslated regions are isotype specific but are conserved in evolution.

1983 • 393 citations

Interleukin-2 stimulates association of protein kinase C with plasma membrane

1985 • 384 citations

Human CSF-1: Molecular Cloning and Expression of 4-kb cDNA Encoding the Human Urinary Protein

1987 • 381 citations

Human vascular smooth muscle cells. Target for and source of tumor necrosis factor.

1989 • 333 citations

Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization.

1984 • 284 citations

Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells.

1986 • 283 citations

Recombinant human TNF alpha stimulates production of granulocyte colony- stimulating factor

1987 • 212 citations

Phospholipid-sensitive Ca2+-dependent protein phosphorylation system in various types of leukemic cells from human patients and in human leukemic cell lines HL60 and K562, and its inhibition by alkyl-lysophospholipid.

1983 • 207 citations

Tumor necrosis factor (TNF)-alpha but not TNF-beta induces secretion of colony stimulating factor for macrophages (CSF-1) by human monocytes

1987 • 191 citations

Recombinant human TNF alpha stimulates production of granulocyte colony- stimulating factor

1987 • 189 citations

Interrelationships of human interferon-gamma with lymphotoxin and monocyte cytotoxin.

1984 • 187 citations

Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody.

1988 • 187 citations

Retinoic acid enhances colony-stimulating factor-induced clonal growth of normal human myeloid progenitor cells in vitro*1

1982 • 178 citations

Interleukin‐1 regulation of hematopoietic growth factor production by human stromal fibroblasts

1988 • 136 citations

Effects of recombinant tumor necrosis factor, lymphotoxin, and immune interferon on proliferation and differentiation of enriched hematopoietic precursor cells.

1988 • 131 citations

Gamma interferon and lymphotoxin, released by activated T cells, synergize to inhibit granulocyte/monocyte colony formation.

1986 • 130 citations

Production of Lymphotoxin and Migration Inhibitory Factor by Established Human Lymphocytic Cell Lines

1970 • 130 citations

Regulation of colony-stimulating activity production. Interactions of fibroblasts, mononuclear phagocytes, and lactoferrin.

1983 • 124 citations

Transcriptional and posttranscriptional modulation of myeloid colony-stimulating factor expression by tumor necrosis factor and other agents.

1988 • 124 citations

Effect of tumor necrosis factor on GTP binding and GTPase activity in HL-60 and L929 cells.

1988 • 101 citations

Tumor necrosis factors alpha and beta differ in their capacities to generate interleukin 1 release from human endothelial cells.

1987 • 99 citations

Disparate effects of tumor necrosis factor-alpha/cachectin and tumor necrosis factor-beta/lymphotoxin on hematopoietic growth factor production and neutrophil adhesion molecule expression by cultured human endothelial cells.

1987 • 87 citations

Tumor necrosis factor and lymphotoxin gene expression in human tumor cell lines.

1988 • 83 citations

Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro.

1988 • 66 citations

Effect of anti-lymphotoxin on cell-mediated cytotoxicity

1976 • 55 citations

Human Lymphotoxin Obtained from Established Lymphoid Lines: Purification Characteristics and Inhibition by Anti-Immunoglobulin

1974 • 41 citations

Studies on in vitro models of cellular immunity: The role of T and B cells in the secretion of lymphotoxin

1973 • 40 citations

Lymphotoxin: An anticarcinogenic lymphokine as measured by inhibition of chemical carcinogen or ultraviolet‐irradiation‐induced transformation of syrian hamster cells

1981 • 37 citations

Lymphokine properties of a lymphoid cultured cell supernatant fraction active in promoting tumor regression

1976 • 36 citations

The susceptibility of guinea pig cells to the colony-inhibitory activity of lymphotoxin during carcinogenesis.

1977 • 32 citations

Production of lymphotoxin and tumour necrosis factor by a T-cell hybridoma.

1987 • 21 citations