Additive regulation of hepatic gene expression by dwarfism and caloric restriction

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1995 • 93,704 citations

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2003 • 4,927 citations

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2002 • 4,142 citations

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2002 • 3,652 citations

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2011 • 1,990 citations

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1997 • 1,468 citations

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2001 • 814 citations

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2002 • 789 citations

Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

1996 • 787 citations

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1997 • 784 citations

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2000 • 613 citations

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2003 • 587 citations

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2003 • 571 citations

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2002 • 560 citations

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2003 • 557 citations

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2000 • 527 citations

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2002 • 464 citations

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1997 • 432 citations

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2001 • 425 citations

Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice

2001 • 421 citations

IGF-I receptor signalling in transformation and differentiation

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2001 • 321 citations

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2003 • 297 citations

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Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME.

1996 • 280 citations

Food restriction eliminates preneoplastic cells through apoptosis and antagonizes carcinogenesis in rat liver.

1994 • 274 citations

Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines.

1998 • 249 citations

Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo.

1996 • 239 citations

Growth Hormone and Prolactin Stimulate Tyrosine Phosphorylation of Insulin Receptor Substrate-1, -2, and -3, Their Association with p85 Phosphatidylinositol 3-Kinase (PI3-kinase), and Concomitantly PI3-kinase Activation via JAK2 Kinase

1998 • 182 citations

Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice

2002 • 179 citations

Senescence Marker Protein-30 Knockout Mouse Liver Is Highly Susceptible to Tumor Necrosis Factor-α- and Fas-Mediated Apoptosis

2002 • 166 citations

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2000 • 162 citations

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1999 • 157 citations

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2003 • 153 citations

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Targeted Disruption of the Gene Encoding Hepatocyte Nuclear Factor 3γ Results in Reduced Transcription of Hepatocyte-Specific Genes

1998 • 137 citations

Prolonged longevity of hypopituitary dwarf mice

2001 • 133 citations

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1999 • 130 citations

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2003 • 129 citations

Lifespan extension by reduction of the growth hormone‐insulin‐like growth factor‐1 axis: relation to caloric restriction

2003 • 122 citations

Gene Expression Patterns in Calorically Restricted Mice: Partial Overlap with Long-Lived Mutant Mice

2002 • 119 citations

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2001 • 109 citations

Generation of Anti-apoptotic Presenilin-2 Polypeptides by Alternative Transcription, Proteolysis, and Caspase-3 Cleavage

1997 • 109 citations

Leptin Reverses the Inhibitory Effect of Caloric Restriction on Longitudinal Growth

2003 • 107 citations

Foxa3 (Hepatocyte Nuclear Factor 3γ) Is Required for the Regulation of Hepatic GLUT2 Expression and the Maintenance of Glucose Homeostasis during a Prolonged Fast

2001 • 106 citations

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2001 • 105 citations

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1998 • 91 citations

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2003 • 70 citations

Array-Based Expression Analysis of Mouse Liver Genes: Effect of Age and of the Longevity Mutant Prop1df

2001 • 56 citations

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2002 • 50 citations

Long-living Ames dwarf mouse hepatocytes readily undergo apoptosis

2003 • 43 citations

Interaction between growth hormone and insulin in the regulation of lipoprotein metabolism in the rat

2002 • 41 citations

Sexual dimorphism and growth hormone induction of murine pheromone-binding proteins

1995 • 34 citations

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2001 • 32 citations

Hepatic Gene Expression Profiling of Streptozotocin-Induced Diabetes

2003 • 31 citations

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1996 • 25 citations

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2003 • 24 citations

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2002 • 19 citations

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1999 • 19 citations

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1998 • 16 citations