Back to search

Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice

Data up to Jan 2025

Published2001
Citations421
References61

Total Citations Per Year

Abstract

References (61)

Aging: A Theory Based on Free Radical and Radiation Chemistry

1956 • 8,252 citations

Molecular chaperones in cellular protein folding

1996 • 3,540 citations

High density synthetic oligonucleotide arrays

1999 • 2,256 citations

The Effect of Retarded Growth Upon the Length of Life Span and Upon the Ultimate Body Size

1935 • 2,189 citations

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1999 • 1,972 citations

The retardation of aging and disease by dietary restriction

1989 • 1,494 citations

Gene Expression Profile of Aging and Its Retardation by Caloric Restriction

1999 • 1,483 citations

The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

1993 • 1,444 citations

Genetic associations with human longevity at the APOE and ACE loci

1994 • 1,079 citations

Gene-expression profile of the ageing brain in mice

2000 • 1,057 citations

The Retardation of Aging in Mice by Dietary Restriction: Longevity, Cancer, Immunity and Lifetime Energy Intake

1986 • 968 citations

Dietary Restriction in Mice Beginning at 1 Year of Age: Effect on Life-Span and Spontaneous Cancer Incidence

1982 • 757 citations

Effects of environmental enrichment on gene expression in the brain

2000 • 602 citations

Targeted Disruption of Heat Shock Transcription Factor 1 Abolishes Thermotolerance and Protection against Heat-inducible Apoptosis

1998 • 517 citations

An essential role in liver development for transcription factor XBP-1

2000 • 503 citations

Molecular chaperones in cellular protein folding

1994 • 497 citations

Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis

2000 • 415 citations

Synthesis and Characterization of Insulin-like Growth Factor-binding Protein (IGFBP)-7

1996 • 363 citations

Book Review Ethical Problems in Dialysis and Transplantation (Developments in Nephrology. Vol. 33.) Edited by Carl M. Kjellstrand and John B. Dossetor. 235 pp., illustrated. Boston, Kluwer Academic, 1992. $108.50. 0-7923-1625-8

1993 • 329 citations

The effects of aging on gene expression in the hypothalamus and cortex of mice

2001 • 318 citations

Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy

1995 • 294 citations

Serum amyloid P-component is an acute-phase reactant in the mouse

1979 • 292 citations

Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review).

1998 • 278 citations

Proapoptotic BH3-only Bcl-2 family members induce cytochromecrelease, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity

2000 • 273 citations

Response of human breast cancer cells to heat shock and chemotherapeutic drugs.

1992 • 247 citations

Assessment of the Role of the Glucocorticoid System in Aging Processes and in the Action of Food Restriction

1991 • 245 citations

Apolipoprotein E and atherosclerosis: insight from animal and human studies

1999 • 214 citations

Aging and drug disposition: an update.

1985 • 187 citations

Aging and the Liver: An Update

1998 • 178 citations

Cellular adhesion molecules: regulation and functional significance in the pathogenesis of liver diseases

1997 • 137 citations

Calories and aging alter gene expression for gluconeogenic, glycolytic, and nitrogen-metabolizing enzymes

1999 • 130 citations

Lysozyme is an inducible marker of macrophage activation in murine tissues as demonstrated by in situ hybridization.

1991 • 114 citations

Caloric restriction alters the feeding response of key metabolic enzyme genes

2001 • 105 citations

Changes in the circulating IGF system during short-term fasting and refeeding in rats

1999 • 103 citations

New aspects of the dietary effect of life prolongation in rodents. What is the role of obesity in aging?

1975 • 101 citations

Deleted in oral cancer‐1 ( doc‐l), a novel oral tumor suppressor gene

1995 • 90 citations

BTG gene expression in the p53-dependent and -independent cellular response to DNA damage

2000 • 88 citations

Long-term food restriction depresses serum thyroid hormone concentrations in the rat

1990 • 86 citations

Age-related changes in the intrinsic rate of apoptosis in livers of diet-restricted and ad libitum-fed B6C3F1 mice.

1995 • 86 citations

Annexin II up-regulates cellular levels of p11 protein by a post-translational mechanisms

1996 • 82 citations

Products of the grg (Groucho-related Gene) Family Can Dimerize through the Amino-terminal Q Domain

1996 • 79 citations

Involvement of molecular chaperones in intracellular protein breakdown

1996 • 72 citations

Human sputum cathepsin B degrades proteoglycan, is inhibited by α2-macroglobulin and is modulated by neutrophil elastase cleavage of cathepsin B precursor and cystatin C

1991 • 62 citations

Effect of aging on aortic expression of the vascular cell adhesionmolecule-1 and atherosclerosis in murine models of atherosclerosis

2000 • 58 citations

Dietary Energy Restriction in Mice Reduces Hepatic Expression of Glucose-Regulated Protein 78 (BiP) and 94 mRNA

1990 • 58 citations

Influence of Age and Caloric Restriction on Expression of Hepatic Genes for Xenobiotic and Oxygen Metabolizing Enzymes in the Mouse

1991 • 53 citations

Dietary Energy Tissue-Specifically Regulates Endoplasmic Reticulum Chaperone Gene Expression in the Liver of Mice ,

1997 • 51 citations

Review article: the stages of gastrointestinal carcinogenesis - application of rodent models to human disease

2000 • 41 citations

Inhibition of Double-Stranded RNA- and Tumor Necrosis Factor Alpha-Mediated Apoptosis by Tetratricopeptide Repeat Protein and Cochaperone P58IPK

1999 • 40 citations

Expression of Ly-6, a marker for highly malignant murine tumor cells, is regulated by growth conditions and stress

1998 • 39 citations

The Rate of Creatine Synthesis in the Isolated, Perfused Rat Liver

1962 • 28 citations

Molecular cloning and characterization of the complementary DNA coding for the B‐chain of murine Clq

1989 • 27 citations

Macrovascular Disease Is Associated With Increased Plasma Apolipoprotein A-IV Levels in NIDDM

1997 • 23 citations

Moderate Caloric Restriction Prevents the Age-Related Decline in Growth Hormone Receptor Signal Transduction

1996 • 23 citations

Caloric Intake Alters the Efficiency of Catalase mRNA Translation in the Liver of Old Female Mice

1998 • 21 citations

Age-related down regulation of hepatic cytochrome P1-450, P3-450, catalase and CuZn-superoxide dismutase RNA

1990 • 20 citations

Short-term fasting and the reversal of the stage of promotion in rat hepatocarcinogenesis: role of cell replication, apoptosis, and gene expression

1999 • 19 citations

Calorie Restriction Delays the Crescentic Glomerulonephritis of SCG/Kj Mice

1998 • 13 citations

Short-term fasting and the reversal of the stage of promotion in rat hepatocarcinogenesis: role of cell replication, apoptosis, and gene expression

1999 • 13 citations

Calorie restriction and iopanoic acid effects on thyroid hormone metabolism

1990 • 13 citations

Influence of aging and poly IC treatment on xenobiolic metabolism in mice

1985 • 11 citations

Cited By (0)

Loading...