Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors

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2001 • 7,259 citations

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

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Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors

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Tumors: Wounds That Do Not Heal

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

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The origin and function of tumor-associated macrophages

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KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

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Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

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Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation.

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Suppression of Myc-Induced Apoptosis in β Cells Exposes Multiple Oncogenic Properties of Myc and Triggers Carcinogenic Progression

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Mast Cell-Deficient W-sash c-kit Mutant KitW-sh/W-sh Mice as a Model for Investigating Mast Cell Biology in Vivo

2005 • 573 citations

Reversible Activation of c-Myc in Skin

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Mast cells and angiogenesis

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Chemokines in cancer

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Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene

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Life and Death of the Pancreatic β Cells

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Perivascular Mast Cells Promote Atherogenesis and Induce Plaque Destabilization in Apolipoprotein E–Deficient Mice

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Perspective: Postnatal Pancreatic β Cell Growth

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CXCL1/Macrophage Inflammatory Protein-2-Induced Angiogenesis In Vivo Is Mediated by Neutrophil-Derived Vascular Endothelial Growth Factor-A

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Contribution of endothelial progenitors and proangiogenic hematopoietic cells to vascularization of tumor and ischemic tissue

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The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1β

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Analysis of the role of chemokines in angiogenesis

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Tissue‐selective mast cell reconstitution and differential lung gene expression in mast cell‐deficient Kit^W‐sh/Kit^W‐sh sash mice

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Overexpression of c-Myc in β-Cells of Transgenic Mice Causes Proliferation and Apoptosis, Downregulation of Insulin Gene Expression, and Diabetes

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W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis

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Expression of CCL5/RANTES by Hodgkin and Reed‐Sternberg cells and its possible role in the recruitment of mast cells into lymphomatous tissue

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CCL7 and CXCL10 Orchestrate Oxidative Stress-Induced Neutrophilic Lung Inflammation

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Human mast cells produce matrix metalloproteinase 9

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Expression of the c-kit (CD117) Molecule in Normal and Malignant Hematopoiesis

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Association of vascular endothelial growth factor and mast cells with angiogenesis in laryngeal squamous cell carcinoma

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Soluble Mediators of Inflammation During Tumor Development

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Urinary levels of monocyte chemo‐attractant protein‐1 correlate with tumour stage and grade in patients with bladder cancer

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Expression of the stem cell factor receptor C-KIT (CD117) in acute leukemias.

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Reversible Kinetic Analysis of Myc Targets In vivo Provides Novel Insights into Myc-Mediated Tumorigenesis

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Induction of c-Myc Expression Suppresses Insulin Gene Transcription by Inhibiting NeuroD/BETA2-mediated Transcriptional Activation

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Physical mapping of the Tec and Gabrb1 loci reveals that the Wsh mutation on mouse chromosome 5 is associated with an inversion

1995 • 58 citations

THE ANION GAP

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Mob-1, a Ras target gene, is overexpressed in colorectal cancer

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Increased Density of Interstitial Mast Cells in Amyloid A Renal Amyloidosis

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Murine Chemokine CXCL2/KC Is a Surrogate Marker for Angiogenic Activity in the Inflammatory Granulation Tissue

2005 • 29 citations