In VitroSelection of Lentivirus Vector-Transduced Human CD34⁺Cells

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

1996 • 1,516 citations

Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection.

1990 • 1,465 citations

Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells.

1989 • 1,220 citations

Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice

1997 • 879 citations

Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy

1996 • 795 citations

Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector

1997 • 732 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

Transduction of Human CD34 ⁺ Cells That Mediate Long-Term Engraftment of NOD/SCID Mice by HIV Vectors

1999 • 648 citations

Selection of Drug-Resistant Bone Marrow Cells in Vivo After Retroviral Transfer of Human MDR 1

1992 • 500 citations

Retrovirally marked CD34-enriched peripheral blood and bone marrow cells contribute to long-term engraftment after autologous transplantation

1995 • 496 citations

Quantitative Analysis Reveals Expansion of Human Hematopoietic Repopulating Cells After Short-term Ex Vivo Culture

1997 • 424 citations

SCID Mouse Models of Human Stem Cell Engraftment

1998 • 320 citations

High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G

1996 • 314 citations

Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: analysis of gene transduction of long-lived progenitors

1994 • 264 citations

Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

1997 • 230 citations

In vivo selection of retrovirally transduced hematopoietic stem cells

1998 • 214 citations

Transfer and expression of the human multiple drug resistance gene into live mice.

1992 • 210 citations

Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice.

1996 • 186 citations

Nucleoside transport in normal and neoplastic cells

1993 • 167 citations

Differential Maintenance of Primitive Human SCID-Repopulating Cells, Clonogenic Progenitors, and Long-Term Culture-Initiating Cells After Incubation on Human Bone Marrow Stromal Cells

1997 • 159 citations

Serial transplantation of methotrexate-resistant bone marrow: protection of murine recipients from drug toxicity by progeny of transduced stem cells

1990 • 141 citations

Methotrexate-resistant Variants of Human Dihydrofolate Reductase with Substitutions of Leucine 22

1995 • 140 citations

Transfer and expression of the human multiple drug resistance gene in human CD34+ cells

1994 • 137 citations

Sustained proliferation, multi‐lineage differentiation and maintenance of primitive human haemopoietic cells in NOD/SCID mice transplanted with human cord blood

1997 • 117 citations

Highly Efficient Transduction of the Green Fluorescent Protein Gene in Human Umbilical Cord Blood Stem Cells Capable of Cobblestone Formation in Long-Term Cultures and Multilineage Engraftment of Immunodeficient Mice

1998 • 115 citations

Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.

1997 • 115 citations

Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer

1994 • 108 citations

A gene transfer strategy for making bone marrow cells resistant to trimetrexate

1996 • 106 citations

Expression of human adenosine deaminase in mice after transplantation of genetically-modified bone marrow

1990 • 93 citations

Human Cord Blood CD34+CD38- Cell Transduction via Lentivirus-Based Gene Transfer Vectors

1999 • 85 citations

Retrovirus-mediated gene transduction into long-term repopulating marrow cells of dogs

1991 • 78 citations

Lymphoid and myeloid differentiation of fetal liver CD34+lineage- cells in human thymic organ culture.

1994 • 74 citations

Sensitization of Hematopoietic Stem and Progenitor Cells to Trimetrexate Using Nucleoside Transport Inhibitors

1997 • 69 citations

Retrovirus-mediated gene transduction into long-term repopulating marrow cells of dogs

1991 • 68 citations

Long-term protection of recipient mice from lethal doses of methotrexate by marrow infected with a double-copy vector retrovirus containing a mutant dihydrofolate reductase.

1994 • 62 citations

Efficient Transduction of Human Lymphocytes and CD34+ Cells via Human Immunodeficiency Virus-Based Gene Transfer Vectors

1999 • 58 citations

Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection.

1995 • 48 citations

Human alkyltransferase-transduced murine myeloid progenitors are enriched in vivo by BCNU treatment of transplanted mice.

1997 • 43 citations

Therapy of mouse leukemia L1210 with combinations of nebularine and nitrobenzylthioinosine 5'-monophosphate.

1981 • 37 citations

Cytokine Prestimulation as a Gene Therapy Strategy: Implications for Using the MDR1 Gene as a Dominant Selectable Marker

1997 • 33 citations

Deleted Work

1955 • 0 citations