Quantitative Analysis Reveals Expansion of Human Hematopoietic Repopulating Cells After Short-term Ex Vivo Culture

The Basic Science of Gene Therapy

1993 • 1,767 citations

Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice

1997 • 879 citations

Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy

1996 • 795 citations

Engraftment of gene–modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

1995 • 622 citations

Cytokine Stimulation of Multilineage Hematopoiesis from Immature Human Cells Engrafted in SCID Mice

1992 • 555 citations

Primitive Human Hematopoietic Cells Are Enriched in Cord Blood Compared With Adult Bone Marrow or Mobilized Peripheral Blood as Measured by the Quantitative In Vivo SCID-Repopulating Cell Assay

1997 • 488 citations

A functional comparison of CD34 + CD38- cells in cord blood and bone marrow

1995 • 456 citations

Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium.

1996 • 393 citations

Reconstitution of Hematopoiesis after High-Dose Chemotherapy by Autologous Progenitor Cells Generated ex Vivo

1995 • 382 citations

Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin.

1996 • 360 citations

Recombinant human stem cell factor enhances the formation of colonies by CD34+ and CD34+lin- cells, and the generation of colony-forming cell progeny from CD34+lin- cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor

1991 • 341 citations

Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice

1994 • 283 citations

Extended long-term culture reveals a highly quiescent and primitive human hematopoietic progenitor population

1996 • 281 citations

Flt3 ligand induces proliferation of quiescent human bone marrow CD34+CD38- cells and maintains progenitor cells in vitro

1996 • 240 citations

Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow.

1992 • 231 citations

Thrombopoietin supports proliferation of human primitive hematopoietic cells in synergy with steel factor and/or interleukin-3

1996 • 220 citations

Department of Genetics

1941 • 186 citations

Normal and leukemic human stem cells assayed in SCID mice

1996 • 163 citations

Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot study [see comments]

1994 • 153 citations

Evaluation of ex vivo expansion potential of cord blood and bone marrow hematopoietic progenitor cells using cell tracking and limiting dilution analysis

1995 • 148 citations

Ex vivo expansion of hematopoietic stem and progenitor cells--robbing Peter to pay Paul? [editorial]

1993 • 129 citations

Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot study [see comments]

1994 • 121 citations

RECONSTITUTION OF HAEMOPOIETIC SYSTEM WITH AUTOLOGOUS MARROW TAKEN DURING RELAPSE OF ACUTE MYELOBLASTIC LEUKAEMIA AND GROWN IN LONG-TERM CULTURE

1986 • 107 citations

Retention of quiescent hematopoietic cells with high proliferative potential during ex vivo stem cell culture

1996 • 81 citations

Gene Transfer to Hematopoietic Cells

1996 • 79 citations

Expansion of myeloid stem cells in culture.

1995 • 37 citations