Glial-neuronal interactions in the neuroendocrine control of mammalian puberty: Facilitatory effects of gonadal steroids

Glutamate-mediated astrocyte–neuron signalling

1994 • 1,688 citations

Epidermal growth factor.

1990 • 1,645 citations

Prostaglandins stimulate calcium-dependent glutamate release in astrocytes

1998 • 1,138 citations

Direct Signaling from Astrocytes to Neurons in Cultures of Mammalian Brain Cells

1994 • 1,000 citations

Gap junctions: New tools, new answers, new questions

1991 • 981 citations

Astrocyte-mediated potentiation of inhibitory synaptic transmission

1998 • 831 citations

Neuronal activity triggers calcium waves in hippocampal astrocyte networks

1992 • 818 citations

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

1991 • 770 citations

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1993 • 744 citations

ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer.

1996 • 675 citations

A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling

1994 • 601 citations

Multimodal Influence of Estrogen upon Gonadotropin-Releasing Hormone Neurons

1998 • 592 citations

Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

1992 • 579 citations

Gap junctions in the brain: where, what type, how many and why?

1993 • 513 citations

Neuregulins and Their Receptors: A Versatile Signaling Module in Organogenesis and Oncogenesis

1997 • 471 citations

New roles for glia

1991 • 464 citations

Functional receptors for neurotransmitters on astroglial cells

1987 • 436 citations

Transmembrane TGF-α precursors activate EGF/TGF-α receptors

1989 • 432 citations

Transforming growth factor-alpha. A model for membrane-anchored growth factors.

1990 • 430 citations

Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3.

1995 • 407 citations

Physiology of Reproduction.

1971 • 395 citations

Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases

1997 • 390 citations

Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4

1997 • 385 citations

Intermolecular association of the p185 protein and EGF receptor modulates EGF receptor function

1990 • 362 citations

Synthesis and release of neuroactive substances by glial cells

1992 • 327 citations

Peptide growth factors elicit estrogen receptor-dependent transcriptional activation of an estrogen-responsive element.

1993 • 322 citations

Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor.

1996 • 305 citations

Ligands for ErbB-family receptors encoded by a neuregulin-like gene

1997 • 288 citations

Neuropeptide Y: a novel neuroendocrine peptide in the control of pituitary hormone secretion, and its relation to luteinizing hormone.

1992 • 233 citations

Glial Fibrillary Acidic Protein: Regulation by Hormones, Cytokines, and Growth Factors

1994 • 230 citations

Neuregulins in Development

1996 • 229 citations

Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-beta.

1996 • 229 citations

Bivalence of EGF-like ligands drives the ErbB signaling network

1997 • 226 citations

Brain Region and Gene Specificity of Neuropeptide Gene Expression in Cultured Astrocytes

1989 • 219 citations

Insulin-Like Growth Factor I: A Possible Metabolic Signal Involved in the Regulation of Female Puberty

1991 • 215 citations

Dynamic neuronal-glial interactions in hypothalamus and pituitary: Implications for control of hormone synthesis and release

1984 • 212 citations

Excitatory Amino Acids: Function and Significance in Reproduction and Neuroendocrine Regulation

1994 • 212 citations

Transformation of NIH 3T3 Cells by HER3 or HER4 Receptors Requires the Presence of HER1 or HER2

1996 • 208 citations

Effects of Gonadal Steroids on the Ultrastructure of GnRH Neurons in the Rhesus Monkey: Synaptic Input and Glial Apposition*

1991 • 206 citations

Epidermal growth factor binding and mitogenic activity on purified populations of cells from the central nervous system

1982 • 206 citations

Calcium signaling of glial cells along mammalian axons

1993 • 204 citations

Estrogen receptor-immunoreactive glia, endothelia, and ependyma in guinea pig preoptic area and median eminence: electron microscopy.

1992 • 198 citations

Neu Differentiation Factor Activation of ErbB-3 and ErbB-4 Is Cell Specific and Displays a Differential Requirement for ErbB-2

1995 • 187 citations

Transforming growth factor-α gene expression in the hypothalamus is developmentally regulated and linked to sexual maturation

1992 • 181 citations

Endocrine Glia: Roles of Glial Cells in the Brain Actions of Steroid and Thyroid Hormones and in the Regulation of Hormone Secretion

1996 • 172 citations

Involvement of transforming growth factor alpha in the release of luteinizing hormone-releasing hormone from the developing female hypothalamus.

1990 • 169 citations

The Epidermal Growth Factor Receptor Couples Transforming Growth Factor-α, Heparin-binding Epidermal Growth Factor-like Factor, and Amphiregulin to Neu, ErbB-3, and ErbB-4

1996 • 167 citations

Epiregulin Is a Potent Pan-ErbB Ligand That Preferentially Activates Heterodimeric Receptor Complexes

1998 • 163 citations

Ependymoneuronal specializations between LHRH fibers and cells of the cerebroventricular system

1985 • 149 citations

Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area

1985 • 146 citations

Neurotransmitter‐mediated signaling between axons and glial cells

1994 • 145 citations

Hypothalamic Astrocytes Respond to Transforming Growth Factor-α with the Secretion of Neuroactive Substances That Stimulate the Release of Luteinizing Hormone-Releasing Hormone¹

1997 • 133 citations

Estradiol Enhances Prostaglandin E₂Receptor Gene Expression in Luteinizing Hormone-Releasing Hormone (LHRH) Neurons and Facilitates the LHRH Response to PGE₂by Activating a Glia-to-Neuron Signaling Pathway

1997 • 122 citations

Neuroendocrine Regulation of the Luteinizing Hormone-Releasing Hormone Pulse Generator in the Rat

1991 • 106 citations

Expression of Epidermal Growth Factor Receptor Changes in the Hypothalamus during the Onset of Female Puberty

1994 • 104 citations

Luteinizing hormone-releasing hormone terminals in the median eminence of rats undergo dramatic changes after gonadectomy, as revealed by electron microscopic image analysis.

1994 • 103 citations

Activation of ErbB4 by the Bifunctional Epidermal Growth Factor Family Hormone Epiregulin Is Regulated by ErbB2

1998 • 99 citations

ErbB2 expression increases the spectrum and potency of ligand-mediated signal transduction through ErbB4

1998 • 98 citations

Region-specific regulation of transforming growth factor alpha (TGF alpha) gene expression in astrocytes of the neuroendocrine brain

1994 • 98 citations

Transforming growth factor alpha contributes to the mechanism by which hypothalamic injury induces precocious puberty.

1991 • 97 citations

Developmental Expression of the Genes Encoding Transforming Growth Factor Alpha and Its Receptor in the Hypothalamus of Female Rhesus Macaques

1994 • 97 citations

17 beta-estradiol mimics ligand activity of the c-erbB2 protooncogene product.

1993 • 89 citations

Prostanoid Receptors

1994 • 81 citations

Type 1 astrocytes influence luteinizing hormone-releasing hormone release from the hypothalamic cell line GT1-1: is transforming growth factor-beta the principle involved?

1995 • 80 citations

Tumor promoter and epidermal growth factor stimulate phosphorylation of the c-erbB-2 gene product in MKN-7 human adenocarcinoma cells.

1988 • 80 citations

Hypothalamic lesions that induce female precocious puberty activate glial expression of the epidermal growth factor receptor gene: differential regulation of alternatively spliced transcripts

1993 • 72 citations

Effects of Insulin-Like Growth Factors I and II and Insulin on the Immortalized Hypothalamic GTI-7 Cell Line

1995 • 71 citations

Targeting transforming growth factor α expression to discrete loci of the neuroendocrine brain induces female sexual precocity

1997 • 70 citations

Basic fibroblast growth factor is a neurotropic factor in GT1 gonadotropin-releasing hormone neuronal cell lines.

1995 • 67 citations

Overexpression of a human transforming growth factor-alpha (TGF alpha) transgene reveals a dual antagonistic role of TGF alpha in female sexual development.

1994 • 66 citations

Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons.

1996 • 66 citations

Synaptic changes in the hypothalamus of the prepuberal female rat administered estrogen

1983 • 64 citations

Transforming growth factor-beta and astrocytic conditioned medium influence luteinizing hormone-releasing hormone gene expression in the hypothalamic cell line GT1.

1996 • 61 citations

Astrocytes cultured from specific brain regions differ in their expression of adrenergic binding sites

1990 • 57 citations

Estrogen-induced synaptic remodelling in adult rat brain is accompanied by the reorganization of neuronal membranes

1987 • 51 citations

C-erbB2/neu transfection induces gap junctional communication incompetence in glial cells.

1996 • 49 citations

Precocious puberty and synaptogenesis in the hypothalamic arcuate nucleus in pregnant mare serum gonadotropin (PMSG) treated immature female rats

1977 • 42 citations

Epidermal growth factor stimulates secretion of rat pituitary luteinizing hormone in vitro

1985 • 41 citations

Gap junction-mediated loops of neuronal-glial interactions

1998 • 40 citations

C-erbB2/neuTransfection Induces Gap Junctional Communication Incompetence in Glial Cells

1996 • 36 citations

Effect of Estrogen on Hypothalamic Transforming Growth Factor Alpha and Gonadotropin-Releasing Hormone Gene Expression in the Female Rhesus Monkey

1998 • 35 citations

Cross-talk between luteinizing hormone-releasing hormone (LHRH) neurons and astroglial cells: developing glia release factors that accelerate neuronal differentiation and stimulate LHRH release from GT1-1 neuronal cell line and LHRH neurons induce astroglia proliferation

1995 • 32 citations

Comparison of the PAP and ABC Immunocytochemical Techniques

1989 • 26 citations

Ultrastructural changes in hypothalamic cells during estrogen-induced gonadotrophin feedback

1992 • 10 citations

The role of growth factors in the neuroendocrine control of female sexual development

1995 • 9 citations