Hypothalamic Astrocytes Respond to Transforming Growth Factor-α with the Secretion of Neuroactive Substances That Stimulate the Release of Luteinizing Hormone-Releasing Hormone¹

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

Epidermal Growth Factor

1979 • 2,964 citations

Blocking of EGF-Dependent Cell Proliferation by EGF Receptor Kinase Inhibitors

1988 • 593 citations

Transforming growth factor-alpha. A model for membrane-anchored growth factors.

1990 • 430 citations

Epidermal growth factor—induced actin remodeling is regulated by 5-lipoxygenase and cyclooxygenase products

1993 • 255 citations

Insulin-Like Growth Factor I: A Possible Metabolic Signal Involved in the Regulation of Female Puberty

1991 • 215 citations

Effects of Gonadal Steroids on the Ultrastructure of GnRH Neurons in the Rhesus Monkey: Synaptic Input and Glial Apposition*

1991 • 206 citations

Transforming growth factor-α gene expression in the hypothalamus is developmentally regulated and linked to sexual maturation

1992 • 181 citations

Epidermal growth factor activates calcium channels by phospholipase A25-lipoxygenase-mediated leukotriene C4 production

1992 • 179 citations

Involvement of transforming growth factor alpha in the release of luteinizing hormone-releasing hormone from the developing female hypothalamus.

1990 • 169 citations

Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area

1985 • 146 citations

Expression of Epidermal Growth Factor Receptor Changes in the Hypothalamus during the Onset of Female Puberty

1994 • 104 citations

Luteinizing hormone-releasing hormone terminals in the median eminence of rats undergo dramatic changes after gonadectomy, as revealed by electron microscopic image analysis.

1994 • 103 citations

Region-specific regulation of transforming growth factor alpha (TGF alpha) gene expression in astrocytes of the neuroendocrine brain

1994 • 98 citations

Transforming growth factor alpha contributes to the mechanism by which hypothalamic injury induces precocious puberty.

1991 • 97 citations

Sexual Dimorphism in the Synaptic Input to Gonadotropin Releasing Hormone Neurons*

1990 • 94 citations

Type 1 astrocytes influence luteinizing hormone-releasing hormone release from the hypothalamic cell line GT1-1: is transforming growth factor-beta the principle involved?

1995 • 80 citations

Effects of Insulin-Like Growth Factors I and II and Insulin on the Immortalized Hypothalamic GTI-7 Cell Line

1995 • 71 citations

Basic fibroblast growth factor is a neurotropic factor in GT1 gonadotropin-releasing hormone neuronal cell lines.

1995 • 67 citations

Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons.

1996 • 66 citations

Measurement of prostaglandins by radioimmunoassay

1987 • 57 citations

Activation of Estradiol-Positive Feedback at Puberty: Estradiol Sensitizes the LHRH-Releasing System at Two Different Biochemical Steps

1986 • 53 citations

Basic fibroblast growth factor regulates the conversion of pro-luteinizing hormone-releasing hormone (Pro-LHRH) to LHRH in immortalized hypothalamic neurons.

1996 • 38 citations

Cross-talk between luteinizing hormone-releasing hormone (LHRH) neurons and astroglial cells: developing glia release factors that accelerate neuronal differentiation and stimulate LHRH release from GT1-1 neuronal cell line and LHRH neurons induce astroglia proliferation

1995 • 32 citations