Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer

2003 • 3,194 citations

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

2007 • 2,215 citations

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

2009 • 1,449 citations

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression

2007 • 1,181 citations

A2A adenosine receptor protects tumors from antitumor T cells

2006 • 923 citations

Adenosine: an endogenous regulator of innate immunity

2003 • 864 citations

Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

2002 • 651 citations

Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

2002 • 604 citations

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

2010 • 530 citations

Coordinated Adenine Nucleotide Phosphohydrolysis and Nucleoside Signaling in Posthypoxic Endothelium

2003 • 480 citations

The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine.

1997 • 419 citations

CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression

2010 • 394 citations

Generation and Accumulation of Immunosuppressive Adenosine by Human CD4+CD25highFOXP3+ Regulatory T Cells

2009 • 363 citations

HIF-1–dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia

2005 • 335 citations

Tumor Cell Death and ATP Release Prime Dendritic Cells and Efficient Anticancer Immunity

2010 • 328 citations

Ecto‐enzyme and signaling functions of lymphocyte CD 7 3

1998 • 322 citations

Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)

2008 • 229 citations

A Noncommercial Dual Luciferase Enzyme Assay System for Reporter Gene Analysis

2000 • 228 citations

The role of CD26/dipeptidyl peptidase IV in cancer

2007 • 195 citations

Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors

1999 • 185 citations

Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto‐ATPase

1995 • 182 citations

Ecto-5′-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells

2007 • 179 citations

Adenosine A_2Areceptor activation inhibits T helper 1 and T helper 2 cell development and effector function

2008 • 173 citations

Increased Ectonucleotidase Expression and Activity in Regulatory T Cells of Patients with Head and Neck Cancer

2009 • 166 citations

A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis

2001 • 166 citations

Macrophage Migration Inhibitory Factor Contributes to the Immune Escape of Ovarian Cancer by Down-Regulating NKG2D

2008 • 155 citations

Upregulation of CD39/NTPDases and P2 receptors in human pancreatic disease

2006 • 124 citations

Deletion of Cd39/Entpd1 Results in Hepatic Insulin Resistance

2008 • 100 citations

In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model

2006 • 91 citations

Ecto‐ATP diphosphohydrolase/CD39 is overexpressed in differentiated human melanomas

1998 • 76 citations

Human breast cancer cell line MDA‐MB‐231 expresses endogenous A_2B adenosine receptors mediating a Ca²⁺ signal

2005 • 76 citations

Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson's Disease

2004 • 75 citations

Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo

2007 • 68 citations

Biophotonic cytotoxicity assay for high-throughput screening of cytolytic killing

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Selective NTPDase2 expression modulates in vivo rat glioma growth

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DNA methylation regulates adenosine A_2A receptor cell surface expression levels

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α,β-Methylene-adenosine 5′-Triphosphate

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Prevalence of the Mercurial-Sensitive EctoATPase in Human Small Cell Lung Carcinoma: Characterization and Partial Purification

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A rapid method for determining ATP by the firefly luciferin-luciferase system

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Maintenance or Consolidation Therapy in Advanced Ovarian Cancer

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Effect of hypoxia and re-oxygenation on cell invasion and adhesion in human ovarian carcinoma cells

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Emerging drugs for ovarian cancer

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A cell-based luciferase-dependent assay for the quantitative determination of free extracellular adenosine with paracrine signaling activity

2010 • 5 citations

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1988 • 3 citations