Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

A new mathematical model for relative quantification in real-time RT-PCR

2001 • 32,396 citations

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

1995 • 5,971 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

Kinetic PCR Analysis: Real-time Monitoring of DNA Amplification Reactions

1993 • 2,177 citations

Purification and Characterization of Hypoxia-inducible Factor 1

1995 • 2,010 citations

Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL

1998 • 1,474 citations

Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation

2000 • 1,209 citations

Hypoxia-inducible factor 1: master regulator of O2 homeostasis

1998 • 1,066 citations

TRANSCRIPTIONAL REGULATION BY CYCLIC AMP

1997 • 967 citations

HIF-1 and human disease: one highly involved factor

2000 • 900 citations

5′-Nucleotidase: molecular structure and functional aspects

1992 • 864 citations

Roles of PLC-β2 and -β3 and PI3Kγ in Chemoattractant-Mediated Signal Transduction

2000 • 825 citations

Molecular Approach to Adenosine Receptors: Receptor-Mediated Mechanisms of Tissue Protection

2001 • 685 citations

Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3

2000 • 615 citations

A Novel Model of Inflammatory Bowel Disease: Mice Deficient for the Multiple Drug Resistance Gene,mdr1a, Spontaneously Develop Colitis

1998 • 570 citations

Hypoxia-Inducible Factor 1–Dependent Induction of Intestinal Trefoil Factor Protects Barrier Function during Hypoxia

2001 • 418 citations

Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1

1999 • 388 citations

5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers.

1993 • 294 citations

CD39 Is an Ecto-(Ca2+,Mg2+)-apyrase

1996 • 290 citations

Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene.

1987 • 289 citations

Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins.

1990 • 271 citations

Neutrophil-derived 5′-Adenosine Monophosphate Promotes Endothelial Barrier Function via CD73-mediated Conversion to Adenosine and Endothelial A2B Receptor Activation

1998 • 225 citations

Hypoxia-Inducible Factor 1-Mediated Inhibition of Peroxisome Proliferator-Activated Receptor α Expression During Hypoxia

2001 • 216 citations

Adenosine receptors.

1992 • 196 citations

Stimulation of the Mitogen-activated Protein Kinase via the A2A-Adenosine Receptor in Primary Human Endothelial Cells

1997 • 187 citations

Role of vasodilator‐stimulated phosphoprotein in protein kinase A‐induced changes in endothelial junctional permeability

2002 • 177 citations

Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia.

1997 • 175 citations

Nucleotide Metabolism by Endothelium

1985 • 164 citations

Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain

2002 • 153 citations

Neutrophil migration across a cultured epithelial monolayer elicits a biphasic resistance response representing sequential effects on transcellular and paracellular pathways

1992 • 144 citations

CD73 is involved in lymphocyte binding to the endothelium: characterization of lymphocyte-vascular adhesion protein 2 identifies it as CD73.

1995 • 144 citations

Phosphorylation-dependent targeting of cAMP response element binding protein to the ubiquitin/proteasome pathway in hypoxia

2000 • 132 citations

Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol‐anchored lymphocyte differentiation antigen ecto‐5′‐nucleotidase (CD73).

1990 • 132 citations

Hypoxia Induces Phosphorylation of the Cyclic AMP Response Element-binding Protein by a Novel Signaling Mechanism

1998 • 129 citations

Chronic Hypoxia Enhances Adenosine Release in Rat PC12 Cells by Altering Adenosine Metabolism and Membrane Transport

2000 • 127 citations

Regulation of Endothelial CD73 by Adenosine: Paracrine Pathway for Enhanced Endothelial Barrier Function

2000 • 119 citations

Thrombosis and Inflammation as Multicellular Processes: Significance of Cell-Cell Interactions

1995 • 117 citations

Identification of Adenosine A2 Receptor-cAMP System in Human Aortic Endothelial Cells

1994 • 101 citations

Intraoperative tissue oximetry in the human gastrointestinal tract

1990 • 99 citations

Role of VASP in reestablishment of epithelial tight junction assembly after Ca²⁺ switch

2002 • 94 citations

Critical Role of cAMP Response Element Binding Protein Expression in Hypoxia-elicited Induction of Epithelial Tumor Necrosis Factor-α

1999 • 91 citations

Studies on the roles of ATP, adenosine and nitric oxide in mediating muscle vasodilatation induced in the rat by acute systemic hypoxia.

1996 • 78 citations

THE IMPACT OF FEMUR FRACTURE WITH ASSOCIATED SOFT TISSUE INJURY ON IMMUNE FUNCTION AND INTESTINAL PERMEABILITY

1996 • 77 citations

Adenosine and Cardioprotection in the Diseased Heart

1999 • 71 citations

Hypoxia enhances stimulus-dependent induction of E-selectin on aortic endothelial cells.

1996 • 68 citations

Epithelial permeability induced by neutrophil transmigration is potentiated by hypoxia: Role of intracellular cAMP

1998 • 59 citations

Isolation and characterization of the promoter of the human 5′-nucleotidase (CD73)-encoding gene

1995 • 57 citations

Characterization of the adenosine receptor in microvascular coronary endothelial cells

1994 • 35 citations

NG-monomethyl-l-arginine inhibits erythropoietin gene expression by stimulating GATA-2

2000 • 31 citations

A novel assay for 5′-nucleotidase using 1,N6-etheno-AMP as substrate, and comments on the properties of the reaction product, ethenoadenosine

1988 • 30 citations

Cardioprotection by Ischemic Preconditioning

1998 • 8 citations