Biophotonic cytotoxicity assay for high-throughput screening of cytolytic killing

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

1968 • 1,363 citations

Lymphocyte-Mediated Cytotoxicity

2002 • 1,079 citations

Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines

1995 • 686 citations

Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.

1994 • 527 citations

Specific Recognition and Killing of Glioblastoma Multiforme by Interleukin 13-Zetakine Redirected Cytolytic T Cells

2004 • 361 citations

Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment.

1995 • 268 citations

CARE-LASS (calcein-release-assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity

1994 • 267 citations

Use of firefly luciferase in atp-related assays of biomass, enzymes, and metabolites

2000 • 260 citations

Receptor for interleukin 13 is a marker and therapeutic target for human high-grade gliomas.

1999 • 249 citations

Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity

1999 • 240 citations

[4] Estimation of biomass in growing cell lines by adenosine triphosphate assay

1986 • 234 citations

A novel flow cytometric assay for quantitation and multiparametric characterization of cell-mediated cytotoxicity

2001 • 212 citations

A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis

2001 • 166 citations

Measurement of cytotoxicity by target cell release and retention of the fluorescent dye bis-carboxyethyl-carboxyfluorescein (BCECF)

1988 • 136 citations

Granzyme B ELISPOT assay for ex vivo measurements of T cell immunity

2000 • 107 citations

Human T Lymphocyte Genetic Modification with Naked DNA

2000 • 102 citations

Comparison of fluorochrome-labeled and 51Cr-labeled targets for natural killer cytotoxicity assay

1989 • 79 citations

A novel cytotoxicity assay to evaluate antigen-specific CTL responses using a colorimetric substrate for Granzyme B

2003 • 66 citations

The fluorolysis assay, a highly sensitive method for measuring the cytolytic activity of T cells at very low numbers

2002 • 47 citations

Comparison of a bioluminescence assay with differential staining cytotoxicity for cytostatic drug testing in vitro in human leukemic cells

1993 • 35 citations

A simple, rapid and sensitive fluorimetric assay for the measurement of cell-mediated cytotoxicity

1995 • 35 citations

BLT esterase activity as an alternative to chromium release in cytotoxic T cell assays

1991 • 32 citations

Accelerating the Pace of Luciferase Reporter Gene Assays

1996 • 23 citations