Targeted Mutagenesis of Smad1 Reveals an Essential Role in Chorioallantoic Fusion

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Controlling TGF-beta signaling.

2000 • 1,806 citations

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

Controlling TGF-β signaling

2000 • 1,522 citations

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.

1995 • 1,118 citations

Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth

1996 • 1,062 citations

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

1996 • 959 citations

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

1999 • 890 citations

Limb alterations in brachypodism mice due to mutations in a new member of the TGFβ-superfamily

1994 • 855 citations

Cell adhesion events mediated by α4 integrins are essential in placental and cardiac development

1995 • 792 citations

Bone morphogenetic proteins in development

2004 • 678 citations

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

1999 • 667 citations

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

1998 • 555 citations

Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice

1995 • 554 citations

A role for Smad6 in development and homeostasis of the cardiovascular system

2000 • 488 citations

Smads and early developmental signaling by the TGFβ superfamily

1998 • 485 citations

Targeted Disruption of Smad3 Reveals an Essential Role in Transforming Growth Factor β-Mediated Signal Transduction

1999 • 475 citations

Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2

1998 • 472 citations

Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects

1999 • 436 citations

Xenopus Mad Proteins Transduce Distinct Subsets of Signals for the TGFβ Superfamily

1996 • 432 citations

Role of Ras and Mapks in TGFβ signaling

2000 • 430 citations

BMP Type II Receptor Is Required for Gastrulation and Early Development of Mouse Embryos

2000 • 413 citations

Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5

1999 • 394 citations

Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation.

1995 • 393 citations

Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.

2000 • 364 citations

Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup

1999 • 343 citations

Positive and negative regulation of TGF-β signaling

2000 • 333 citations

Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases

1998 • 291 citations

Smad1 Recognition and Activation by the ALK1 Group of Transforming Growth Factor-β Family Receptors

1999 • 219 citations

The Type II Activin Receptors Are Essential for Egg Cylinder Growth, Gastrulation, and Rostral Head Development in Mice

1999 • 192 citations

Targeted Disruption in Murine Cells Reveals Variable Requirement for Smad4 in Transforming Growth Factor β-related Signaling

2000 • 161 citations

TGF-β: A Critical Modulator of Immune Cell Function

1997 • 160 citations

Smad5 Is Essential for Left–Right Asymmetry in Mice

2000 • 151 citations

Vascularization in the murine allantois occurs by vasculogenesis without accompanying erythropoiesis

1998 • 119 citations

Expression of Smad1 and Smad2 during embryogenesis suggests a role in organ development

1998 • 58 citations

BMP 7 Is Required for Nephrogenesis, Eye Development, and Skeletal Patterninga

1996 • 55 citations

1 The Murine Allantois

1998 • 47 citations

Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues

2000 • 35 citations

The Smads

1999 • 31 citations

Axial rotation in rat embryos: Morphological analysis and microsurgical study on the role of the allantois

1995 • 18 citations

Whole Mount In Situ Hybridization to Study Gene Expression During Mouse Development

2003 • 15 citations

A molecular basis for Smad specificity

1999 • 14 citations

Microsurgical study on the mechanisms determining sidedness of axial rotation in rat embryos

1993 • 12 citations

A molecular basis for Smad specificity

1999 • 10 citations