A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

1994 • 1,589 citations

Genetic variants and strains of the laboratory mouse

1990 • 1,519 citations

Pax-6, a murine paired box gene, is expressed in the developing CNS

1991 • 1,226 citations

Mouse Small eye results from mutations in a paired-like homeobox-containing gene

1991 • 1,124 citations

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

1994 • 1,056 citations

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

1993 • 908 citations

Organogenesis of the kidney

1987 • 904 citations

Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

1990 • 837 citations

Expression of the c-ret proto-oncogene during mouse embryogenesis

1993 • 831 citations

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

1994 • 769 citations

Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

1986 • 761 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

The role ofPax-6in eye and nasal development

1995 • 660 citations

Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse

1991 • 646 citations

Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S

1980 • 618 citations

Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A)

1990 • 616 citations

Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation

1993 • 606 citations

Human Type II Receptor for Bone Morphogenic Proteins (BMPs): Extension of the Two-Kinase Receptor Model to the BMPs

1995 • 602 citations

Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system

1990 • 562 citations

OP-1 cDNA encodes an osteogenic protein in the TGF-beta family.

1990 • 554 citations

Cloning and characterization of a human type II receptor for bone morphogenetic proteins.

1995 • 551 citations

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects.

1995 • 510 citations

The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

1994 • 486 citations

The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGFβ superfamily

1992 • 483 citations

decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo

1992 • 480 citations

Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland

1990 • 479 citations

Organogenesis of the Kidney

1987 • 473 citations

Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb

1994 • 465 citations

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development.

1989 • 440 citations

Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor

1993 • 433 citations

Pax: A murine multigene family of paired box-containing genes

1991 • 427 citations

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development

1995 • 424 citations

FGF-4 and BMP-2 have opposite effects on limb growth

1993 • 377 citations

[51] Gene targeting in embryonic stem cells

1993 • 320 citations

Apoptosis in metanephric development.

1992 • 310 citations

Vertebrate Embryonic Induction: Mesodermal and Neural Patterning

1994 • 286 citations

Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo.

1993 • 283 citations

The BMP proteins in bone formation and repair

1992 • 273 citations

BMP5 and the Molecular, Skeletal, and Soft-Tissue Alterations in short ear Mice

1994 • 247 citations

Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals.

1993 • 227 citations

Tissue interactions and development

1973 • 223 citations

The Msh-like homeobox genes define domains in the developing vertebrate eye

1991 • 217 citations

Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin

1993 • 215 citations

Studies on the development of the eye cup and optic nerve in normal mice and in mutants with congenital optic nerve aplasia

1979 • 209 citations

Embryonic lens induction: shedding light on vertebrate tissue determination

1992 • 207 citations

Ribonuclease Protection Assay

1993 • 207 citations

Localization of Osteogenic Protein-1 (Bone Morphogenetic Protein-7) during Human Embryonic Development: High Affinity Binding to Basement Membranes

1994 • 202 citations

Murine osteogenic protein (OP-1): High levels of mRNA in kidney

1991 • 184 citations

Small eye (Sey): a mouse model for the genetic analysis of craniofacial abnormalities

1988 • 182 citations

Production and analysis of chimeric mice

1987 • 175 citations

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

1993 • 172 citations

The initiation of the limb bud: Growth factors, Hox genes, and retinoids

1995 • 170 citations

Mechanisms of drosophila retinal morphogenesis: The virtues of being progressive

1995 • 167 citations

Apoptotic cell death induced by optic nerve lesion in the neonatal rat

1994 • 159 citations

Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins.

1991 • 159 citations

The DVR gene family in embryonic development

1991 • 159 citations

The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducers.

1994 • 145 citations

The decapentaplegic gene: a TGF-β homologue controlling pattern formation in Drosophila

1989 • 144 citations

Studies on an anophthalmic strain of mice I. Embryology of the eye region

1941 • 136 citations

Development of Dickie's small eye, a mutation in the house mouse

1979 • 78 citations

Mechanism of the pleiotropic effects of the short‐ear mutant gene in the mouse

1968 • 70 citations

Studies on an anophthalmic strain of mice

1978 • 62 citations

Molecular genetics of ocular disease

1995 • 52 citations