Specificity of TRAF3 in Its Negative Regulation of the Noncanonical NF-κB Pathway

Signaling to NF-κB

2004 • 3,768 citations

Mechanisms Underlying Ubiquitination

2001 • 3,555 citations

The two NF-κB activation pathways and their role in innate and adaptive immunity

2004 • 2,476 citations

Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

2000 • 1,801 citations

Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations

1999 • 1,464 citations

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40

1995 • 1,046 citations

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

2005 • 915 citations

The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways

2002 • 891 citations

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

2005 • 847 citations

BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells

2002 • 674 citations

The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes

2004 • 674 citations

Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death

1998 • 597 citations

All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction

2002 • 594 citations

Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of Nuclear Factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1997 • 552 citations

The signaling adaptors and pathways activated by TNF superfamily

2003 • 481 citations

Regulation of the NF-κB-inducing Kinase by Tumor Necrosis Factor Receptor-associated Factor 3-induced Degradation

2004 • 449 citations

Tumor Necrosis Factor Receptor-Associated Factor (TRAF) Family: Adapter Proteins That Mediate Cytokine Signaling

2000 • 436 citations

CD40 regulates the processing of NF-kappaB2 p100 to p52

2002 • 435 citations

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

2006 • 411 citations

TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor

1996 • 343 citations

The alternative NF-κB pathway from biochemistry to biology: Pitfalls and promises for future drug development

2006 • 340 citations

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling.

1996 • 339 citations

Anatomy of TRAF2

1996 • 302 citations

TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation.

1996 • 283 citations

TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-κB pathway by TRAF-binding TNFRs

2005 • 232 citations

TRAF2 Differentially Regulates the Canonical and Noncanonical Pathways of NF-κB Activation in Mature B Cells

2004 • 211 citations

Gastric Hyperplasia and Increased Proliferative Responses of Lymphocytes in Mice Lacking the COOH-terminal Ankyrin Domain of NF-κB2

1997 • 178 citations

TRAF1 Is a Negative Regulator of TNF Signaling

2001 • 170 citations

Rescue of TRAF3-null mice by p100 NF-κB deficiency

2006 • 164 citations

Act1, a Negative Regulator in CD40- and BAFF-Mediated B Cell Survival

2004 • 141 citations

Complete structural characterisation of the mammalian and Drosophila TRAF genes: implications for TRAF evolution and the role of RING finger splice variants

2000 • 87 citations

Tumor Necrosis Factor Receptor (TNFR)-associated Factor 2A (TRAF2A), a TRAF2 Splice Variant with an Extended RING Finger Domain That Inhibits TNFR2-mediated NF-κB Activation

1998 • 65 citations

An Intact Zinc Ring Finger Is Required for Tumor Necrosis Factor Receptor-associated Factor-mediated Nuclear Factor-κB Activation but Is Dispensable for c-Jun N-terminal Kinase Signaling

1998 • 63 citations

Identification of a TRAF (TNF Receptor-Associated Factor) Gene in Caenorhabditis elegans

1998 • 54 citations

Downstream Regulator TANK Binds to the CD40 Recognition Site on TRAF3

2002 • 51 citations

TRAF2 Plays a Key, Nonredundant Role in LIGHT-Lymphotoxin β Receptor Signaling

2005 • 48 citations

TNAP, a Novel Repressor of NF-κB-inducing Kinase, Suppresses NF-κB Activation

2004 • 33 citations