Act1, a Negative Regulator in CD40- and BAFF-Mediated B Cell Survival

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

Missing Pieces in the NF-κB Puzzle

2002 • 3,560 citations

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1997 • 2,137 citations

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

1997 • 2,048 citations

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

2001 • 2,027 citations

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

1997 • 1,802 citations

Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

2000 • 1,801 citations

Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations

1999 • 1,464 citations

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

1997 • 1,198 citations

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

2000 • 1,171 citations

Identification and Characterization of an IκB Kinase

1997 • 1,166 citations

The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway

1999 • 1,163 citations

The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

1994 • 1,099 citations

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

2001 • 1,048 citations

BAFF and APRIL: A Tutorial on B Cell Survival

2003 • 946 citations

BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF

2001 • 889 citations

Mice deficient for the CD40 ligand

1994 • 753 citations

BAFF: A fundamental survival factor for B cells

2002 • 694 citations

TAB2, a Novel Adaptor Protein, Mediates Activation of TAK1 MAPKKK by Linking TAK1 to TRAF6 in the IL-1 Signal Transduction Pathway

2000 • 589 citations

Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

2000 • 579 citations

BAFF/BLyS Receptor 3 Binds the B Cell Survival Factor BAFF Ligand through a Discrete Surface Loop and Promotes Processing of NF-κB2

2002 • 468 citations

Regulation of the NF-κB-inducing Kinase by Tumor Necrosis Factor Receptor-associated Factor 3-induced Degradation

2004 • 449 citations

CD40 regulates the processing of NF-kappaB2 p100 to p52

2002 • 435 citations

Activation and accumulation of B cells in TACI-deficient mice

2001 • 409 citations

Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice

2001 • 407 citations

Loss of TACI Causes Fatal Lymphoproliferation and Autoimmunity, Establishing TACI as an Inhibitory BLyS Receptor

2003 • 400 citations

TALL-1 is a novel member of the TNF family that is down-regulated by mitogens

1999 • 367 citations

IRAK-mediated Translocation of TRAF6 and TAB2 in the Interleukin-1-induced Activation of NFκB

2001 • 211 citations

BAFF is a survival and maturation factor for mouse B cells

2002 • 201 citations

Interleukin-1 (IL-1) Receptor-Associated Kinase Leads to Activation of TAK1 by Inducing TAB2 Translocation in the IL-1 Signaling Pathway

2001 • 195 citations

TAK1 mediates an activation signal from toll‐like receptor(s) to nuclear factor‐κB in lipopolysaccharide‐stimulated macrophages

2000 • 188 citations

IκB Kinase Signaling Is Essential for Maintenance of Mature B Cells

2002 • 179 citations

IKKβ Is Required for Peripheral B Cell Survival and Proliferation

2003 • 177 citations

Act1, an NF-κB-activating protein

2000 • 164 citations

CIKS, a connection to IκB kinase and stress-activated protein kinase

2000 • 153 citations

TNFR-Associated Factor-3 Is Associated With BAFF-R and Negatively Regulates BAFF-R-Mediated NF-κB Activation and IL-10 Production

2002 • 144 citations

Requirement for TRAF3 in Signaling by LMP1 But Not CD40 in B Lymphocytes

2004 • 131 citations

Functional Role of CD40 and Its Ligand

1997 • 123 citations

Genetic linkage of IgG autoantibody production in relation to lupus nephritis in New Zealand hybrid mice.

1996 • 122 citations

Tumor Necrosis Factor Receptor-associated Factor 2 (TRAF2)-deficient B Lymphocytes Reveal Novel Roles for TRAF2 in CD40 Signaling

2003 • 118 citations

Signaling by CD40 and its Mimics in B Cell Activation

2001 • 115 citations

Cutting Edge: Contrasting Roles of TNF Receptor-Associated Factor 2 (TRAF2) and TRAF3 in CD40-Activated B Lymphocyte Differentiation

1999 • 103 citations

CD40-Mediated Regulation of Immune Responses by TRAF-Dependent and TRAF-Independent Signaling Mechanisms

2001 • 100 citations

Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice.

1998 • 78 citations

Lineage-Restricted Function of Nuclear Factor κB–Inducing Kinase (Nik) in Transducing Signals via Cd40

2000 • 69 citations

Role of NFκB activator Act1 in CD40-mediated signaling in epithelial cells

2002 • 65 citations

Monoclonal anti-histone autoantibodies derived from murine models of lupus.

1984 • 64 citations

IFN Regulatory Factor-1 Is Required for the Up-Regulation of the CD40-NF-κB Activator 1 Axis During Airway Inflammation

2003 • 30 citations