Identification of a TRAF (TNF Receptor-Associated Factor) Gene in Caenorhabditis elegans

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

1996 • 3,854 citations

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

1995 • 2,436 citations

The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation

1995 • 1,979 citations

TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

1996 • 1,976 citations

A novel domain within the 55 kd TNF receptor signals cell death

1993 • 1,302 citations

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1994 • 1,043 citations

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

1995 • 990 citations

RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1995 • 964 citations

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

1993 • 857 citations

A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway

1996 • 822 citations

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1997 • 791 citations

Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of Nuclear Factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1997 • 552 citations

Involvement of CRAF1, a relative of TRAF, in CD40 signaling

1995 • 454 citations

Transducers of life and death: TNF receptor superfamily and associated proteins.

1996 • 423 citations

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation.

1996 • 414 citations

A novel RING finger protein interacts with the cytoplasmic domain of CD40.

1994 • 345 citations

TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor

1996 • 343 citations

4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB

1998 • 342 citations

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling.

1996 • 339 citations

Herpesvirus Entry Mediator, a Member of the Tumor Necrosis Factor Receptor (TNFR) Family, Interacts with Members of the TNFR-associated Factor Family and Activates the Transcription Factors NF-κB and AP-1

1997 • 294 citations

TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation.

1996 • 283 citations

Targeted Disruption of TRAF3 Leads to Postnatal Lethality and Defective T-Dependent Immune Responses

1996 • 239 citations

CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival

1997 • 224 citations

Induction of Nuclear Factor κB by the CD30 Receptor Is Mediated by TRAF1 and TRAF2

1997 • 214 citations

I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction.

1996 • 210 citations

Tumor Necrosis Factor Receptor-associated Factor (TRAF) 5 and TRAF2 Are Involved in CD30-mediated NFκB Activation

1997 • 204 citations

TRAF-interacting Protein (TRIP): A Novel Component of the Tumor Necrosis Factor Receptor (TNFR)- and CD30-TRAF Signaling Complexes That Inhibits TRAF2-mediated NF-κB Activation

1997 • 196 citations

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site.

1997 • 183 citations

A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40

1995 • 177 citations

Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB

1997 • 168 citations

T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors.

1996 • 165 citations

A Regulatory Role for TRAF1 in Antigen-induced Apoptosis of T Cells

1997 • 132 citations

Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6) Stimulates Extracellular Signal–regulated Kinase (ERK) Activity in CD40 Signaling Along a Ras-independent Pathway

1998 • 120 citations

Tumor necrosis factor receptor-associated factor (TRAF)-1, TRAF-2, and TRAF-3 interactin vivowith the CD30 cytoplasmic domain; TRAF-2 mediates CD30-induced nuclear factor kappa B activation

1996 • 78 citations

Association of a RING finger protein with the cytoplasmic domain of the human type-2 tumour necrosis factor receptor

1995 • 43 citations