Functional Interaction between the Mouse Notch1 Intracellular Region and Histone Acetyltransferases PCAF and GCN5

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

1990 • 1,835 citations

Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome

1999 • 1,774 citations

Structure and ligand of a histone acetyltransferase bromodomain

1999 • 1,625 citations

PEST sequences and regulation by proteolysis

1996 • 1,606 citations

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1998 • 1,600 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

Signalling downstream of activated mammalian Notch

1995 • 1,375 citations

Steroid receptor coactivator-1 is a histone acetyltransferase

1997 • 1,245 citations

Coactivator and corepressor complexes in nuclear receptor function

1999 • 909 citations

Hes1 and Hes5 as Notch effectors in mammalian neuronal differentiation

1999 • 817 citations

Nuclear Access and Action of Notch In Vivo

1998 • 730 citations

The Notch1 receptor is cleaved constitutively by a furin-like convertase

1998 • 720 citations

Jagged: A mammalian ligand that activates notch1

1995 • 617 citations

Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane

1997 • 615 citations

Histone acetylases and deacetylases in cell proliferation

1999 • 598 citations

Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity.

1995 • 594 citations

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

1998 • 587 citations

Activation of PPARγ Coactivator-1 Through Transcription Factor Docking

1999 • 584 citations

Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

1996 • 571 citations

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

1994 • 483 citations

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H)

1995 • 476 citations

Histone acetylation: chromatin in action

1997 • 475 citations

Mediation of Epstein-Barr Virus EBNA2 Transactivation by Recombination Signal-Binding Protein J _κ

1994 • 462 citations

Truncated Mammalian Notch1 Activates CBF1/RBPJk-Repressed Genes by a Mechanism Resembling That of Epstein-Barr Virus EBNA2

1996 • 459 citations

The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

1995 • 430 citations

Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei.

1993 • 421 citations

The histone acetylase PCAF is a nuclear receptor coactivator

1998 • 389 citations

Regulation of Histone Acetyltransferases p300 and PCAF by the bHLH Protein Twist and Adenoviral Oncoprotein E1A

1999 • 372 citations

A Viral Mechanism for Inhibition of p300 and PCAF Acetyltransferase Activity

1999 • 343 citations

Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation

1998 • 328 citations

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex

1999 • 301 citations

Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives

1997 • 289 citations

A Human RNA Polymerase II Complex Containing Factors That Modify Chromatin Structure

1998 • 277 citations

Delta-induced Notch Signaling Mediated by RBP-J Inhibits MyoD Expression and Myogenesis

1999 • 268 citations

Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless.

1994 • 218 citations

Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos

1998 • 217 citations

Epstein–Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter

2000 • 216 citations

The shortest path from the surface to the nucleus: RBP‐Jκ/Su(H) transcription factor

1996 • 207 citations

Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region

1998 • 203 citations

Isolation and Functional Analysis of a cDNA for Human Jagged2, a Gene Encoding a Ligand for the Notch1 Receptor

1997 • 192 citations

Identification of Human Proteins Functionally Conserved with the Yeast Putative Adaptors ADA2 and GCN5

1996 • 182 citations

Identification of TATA-binding Protein-free TAFII-containing Complex Subunits Suggests a Role in Nucleosome Acetylation and Signal Transduction

1999 • 181 citations

A Human SPT3-TAFII31-GCN5-L Acetylase Complex Distinct from Transcription Factor IID

1998 • 179 citations

Oncogenic Forms of NOTCH1 Lacking Either the Primary Binding Site for RBP-Jκ or Nuclear Localization Sequences Retain the Ability to Associate with RBP-Jκ and Activate Transcription

1997 • 176 citations

Mammalian GCN5 and P/CAF Acetyltransferases Have Homologous Amino-Terminal Domains Important for Recognition of Nucleosomal Substrates

1998 • 162 citations

The 400 kDa Subunit of the PCAF Histone Acetylase Complex Belongs to the ATM Superfamily

1998 • 160 citations

Epstein-Barr Virus Nuclear Antigen 3C Interacts with Histone Deacetylase To Repress Transcription

1999 • 153 citations

NF-Y Is Associated with the Histone Acetyltransferases GCN5 and P/CAF

1998 • 145 citations

PCAF Interacts with Tax and Stimulates Tax Transactivation in a Histone Acetyltransferase-Independent Manner

1999 • 134 citations

RBP-L, a Transcription Factor Related to RBP-Jκ

1997 • 130 citations

E1A directly binds and regulates the P/CAF acetyltransferase

1998 • 124 citations

Cloning of Drosophila GCN5: Conserved features among metazoan GCN5 family members

1998 • 108 citations

The Histone Acetylase PCAF Is a Phorbol-Ester-Inducible Coactivator of the IRF Family That Confers Enhanced Interferon Responsiveness

1999 • 108 citations

Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor.

1996 • 91 citations

Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors

1999 • 91 citations

RBP-J_krepression activity is mediated by a co-repressor and antagonized by the Epstein-Barr virus transcription factor EBNA2

1995 • 83 citations

Two Novel Krüppel-associated Box-containing Zinc-finger Proteins, KRAZ1 and KRAZ2, Repress Transcription through Functional Interaction with the Corepressor KAP-1 (TIF1β/KRIP-1)

1999 • 81 citations

Functional Replacement of the Intracellular Region of the Notch1 Receptor by Epstein-Barr Virus Nuclear Antigen 2

1998 • 77 citations

Long-distance transcriptional enhancement by the histone acetyltransferase PCAF

1998 • 64 citations

A region of herpes simplex virus VP16 can substitute for a transforming domain of Epstein-Barr virus nuclear protein 2.

1992 • 52 citations

Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer invivo

1998 • 34 citations

Millimetre and submillimetre measurements of the Crab Nebula

1979 • 9 citations