N-methyl-d-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

Alzheimer's Disease: Cell-Specific Pathology Isolates the Hippocampal Formation

1984 • 2,199 citations

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

1986 • 1,978 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

NMDA receptors - their role in long-term potentiation

1987 • 1,177 citations

Excitotoxity and the NMDA receptor

1987 • 1,053 citations

Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists

1988 • 983 citations

Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors

1984 • 905 citations

The Primate Hippocampal Formation: Evidence for a Time-Limited Role in Memory Storage

1990 • 883 citations

Hypoglycemia-Induced Neuronal Damage Prevented by an N -Methyl-D-Aspartate Antagonist

1985 • 673 citations

Perforant pathway changes and the memory impairment of Alzheimer's disease

1986 • 665 citations

β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1990 • 620 citations

Quantitative Methods in Morphology

1967 • 500 citations

Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.

1988 • 495 citations

Anatomic organization and physiology of the limbic cortex

1990 • 481 citations

Quantitative assessment of cortical synaptic density in Alzheimer's disease

1990 • 415 citations

NMDA Receptor Losses in Putamen from Patients with Huntington's Disease

1988 • 401 citations

Dementia of the Alzheimer's Type: Changes in Hippocampal L‐[³H]Glutamate Binding

1987 • 281 citations

Topographic distribution of neurofibrillary tangles and granulovacuolar degeneration in hippocampal cortex of aging and demented patients. A quantitative study

1978 • 252 citations

Alzheimer's disease: Glutamate depletion in the hippocampal perforant pathway zone

1987 • 221 citations

Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease

1986 • 215 citations

Mechanisms of blockade of excitatory amino acid receptor channels

1990 • 199 citations

Alzheimer's disease: Changes in hippocampal N-methyl-d-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors—an autoradiographic study

1990 • 195 citations

Down's dyndrome and Alzheimer's disease: dendritic spine counts in the hippocampus

1990 • 194 citations

Phencyclidine and related drugs bind to the activated receptor-channel complex in rat brain membranes

1987 • 170 citations

Region-specific loss of glutamate innervation in Alzheimer's disease

1987 • 147 citations

Clinical Neurology of Aging

1985 • 141 citations

Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel

1987 • 140 citations

Excitatory amino acid receptors in the human cerebral cortex: A quantitative autoradiographic study comparing the distributions of [3H]TCP, [3H]glycine,l-[3H]glutamate, [3H]AMPA and [3H]kainic acid binding sites

1989 • 135 citations

HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site

1989 • 128 citations

Reduced Glycine Stimulation of [³H]MK‐801 Binding in Alzheimer's Disease

1989 • 117 citations

Morphological adaptive response of the synaptic junctional zones in the human dentate gyrus during aging and Alzheimer's disease

1990 • 116 citations

Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: an autoradiographic study of the hippocampus

1991 • 113 citations

Glycine potentiates [3H]TCP binding to rat cortical membranes

1987 • 105 citations

Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias.

1990 • 100 citations

Loss of hippocampal [3H]TCP binding in Alzheimer's disease

1987 • 97 citations

Brain membrane fluidity and lipid peroxidation in Alzheimer's disease

1990 • 95 citations

Regional distribution of pre- and postsynaptic glutamatergic function in Alzheimer's disease

1988 • 85 citations

[3H]TCP binding sites in Alzheimer's disease

1987 • 83 citations

Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors

1991 • 79 citations

Regional changes in [3H]d-aspartate and [3H]TCP binding sites in Alzheimer's disease brains

1988 • 76 citations

Strain-dependent decrease in glutamate binding to the acid receptor during aging

1989 • 73 citations

Interaction of L-glutamate and magnesium with phencyclidine recognition sites in rat brain: evidence for multiple affinity states of the phencyclidine/N-methyl-D-aspartate receptor complex.

1987 • 71 citations

A review of the in vitro and in vivo neurochemical characterization of the NMDA/PCP/Glycine/Ion channel receptor macrocomplex

1990 • 70 citations

Loss of glycine-dependent radioligand binding to the receptor complex in patients with Alzheimer's disease

1989 • 63 citations

Glycine modulation of the phencyclidine binding site in mammalian brain

1988 • 63 citations

Molecular Insights into Alzheimer's Disease

1989 • 62 citations

The presubicular region in Alzheimer's disease: topography of amyloid deposits and neurofibrillary changes

1989 • 57 citations

Is senile dementia of the Alzheimer type associated with hippocampal plasticity?

1988 • 56 citations

Differential modification of muscarinic cholinergic receptors in the hippocampus of patients with Alzheimer's disease: an autoradiographic study

1988 • 53 citations

Introduction to stereology and morphometry

1967 • 47 citations

Alzheimer's Disease

1989 • 47 citations

Plastic response of hippocampal excitatory amino acid receptors to deafferentation and reinnervation

1990 • 45 citations

[3H]MK-801 binding in Alzheimer's disease

1988 • 44 citations

N-methyl-D-aspartate receptors and Alzheimer's disease

1989 • 38 citations

[³H]N‐[1‐(2‐Thienyl)cyclohexyl]‐3,4‐Piperidine ([³H]TCP) Binding in Human Frontal Cortex: Decreases in Alzheimer‐Type Dementia

1990 • 35 citations

Characterisation of the Glycine Modulatory Site of the N‐Methyl‐<scp>d</scp>‐Aspartate Receptor‐Ionophore Complex in Human Brain

1991 • 34 citations

Untitled

1984 • 21 citations