Chronic stress: Implications for neuronal morphology, function and neurogenesis

Stress and the brain: from adaptation to disease

2005 • 4,321 citations

Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

2003 • 4,175 citations

Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

2000 • 3,047 citations

Functional neurogenesis in the adult hippocampus

2002 • 2,813 citations

Maternal Care, Gene Expression, and the Transmission of Individual Differences in Stress Reactivity Across Generations

2001 • 2,665 citations

Brain Corticosteroid Receptor Balance in Health and Disease*

1998 • 2,442 citations

THE AMYGDALA MODULATES THE CONSOLIDATION OF MEMORIES OF EMOTIONALLY AROUSING EXPERIENCES

2004 • 2,192 citations

STRESS AND HIPPOCAMPAL PLASTICITY

1999 • 2,023 citations

Long-Term Potentiation and Memory

2004 • 1,888 citations

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

1999 • 1,756 citations

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

2006 • 1,724 citations

Chronic Stress Induces Contrasting Patterns of Dendritic Remodeling in Hippocampal and Amygdaloid Neurons

2002 • 1,607 citations

Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma

2002 • 1,579 citations

Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

2001 • 1,554 citations

Protection and Damage from Acute and Chronic Stress: Allostasis and Allostatic Overload and Relevance to the Pathophysiology of Psychiatric Disorders

2004 • 1,516 citations

Hippocampal Volume and Depression: A Meta-Analysis of MRI Studies

2004 • 1,491 citations

Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation

1997 • 1,468 citations

The stressed hippocampus, synaptic plasticity and lost memories

2002 • 1,458 citations

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus

1995 • 1,429 citations

Milestones of neuronal development in the adult hippocampus

2004 • 1,389 citations

Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress

1998 • 1,386 citations

CRF and CRF Receptors: Role in Stress Responsivity and Other Behaviors

2004 • 1,235 citations

Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons

1992 • 1,215 citations

Untreated Depression and Hippocampal Volume Loss

2003 • 1,140 citations

Brain Corticosteroid Receptor Balance in Health and Disease

1998 • 1,138 citations

Drugs of Abuse and Stress Trigger a Common Synaptic Adaptation in Dopamine Neurons

2003 • 1,133 citations

Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging

1985 • 1,129 citations

Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine

2001 • 1,082 citations

Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons

1990 • 1,013 citations

Early adverse experience as a developmental risk factor for later psychopathology: Evidence from rodent and primate models

2001 • 993 citations

Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus

1994 • 986 citations

Adult Neurogenesis: From Precursors to Network and Physiology

2005 • 961 citations

Stress-Induced Alterations in Prefrontal Cortical Dendritic Morphology Predict Selective Impairments in Perceptual Attentional Set-Shifting

2006 • 895 citations

Learning under stress: how does it work?

2006 • 893 citations

Chronic Psychosocial Stress Causes Apical Dendritic Atrophy of Hippocampal CA3 Pyramidal Neurons in Subordinate Tree Shrews

1996 • 849 citations

Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Involvement of glucocorticoid secretion and excitatory amino acid receptors

1995 • 849 citations

On the Interactions of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Sleep: Normal HPA Axis Activity and Circadian Rhythm, Exemplary Sleep Disorders

2005 • 797 citations

Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment

2003 • 796 citations

Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis

2003 • 788 citations

Vasopressin and Oxytocin Excite Distinct Neuronal Populations in the Central Amygdala

2005 • 783 citations

Nongenomic Glucocorticoid Inhibition via Endocannabinoid Release in the Hypothalamus: A Fast Feedback Mechanism

2003 • 774 citations

Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment

2006 • 770 citations

Repeated Stress Induces Dendritic Spine Loss in the Rat Medial Prefrontal Cortex

2005 • 768 citations

Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone

2005 • 749 citations

Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex

2004 • 749 citations

Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement

2000 • 747 citations

Stress, Glucocorticoids, and Damage to the Nervous System: The Current State of Confusion

1996 • 737 citations

Chronic stress alters dendritic morphology in rat medial prefrontal cortex

2004 • 713 citations

Stress and adult neurogenesis

2006 • 685 citations

Inverted‐U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation

1992 • 671 citations

Glucocorticoids and the regulation of memory consolidation

2000 • 667 citations

Repeated restraint stress suppresses neurogenesis and induces biphasic PSA‐NCAM expression in the adult rat dentate gyrus

2003 • 641 citations

Stress duration modulates the spatiotemporal patterns of spine formation in the basolateral amygdala

2005 • 627 citations

Short‐term and long‐term survival of new neurons in the rat dentate gyrus

2003 • 616 citations

Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2

2000 • 591 citations

Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration

2001 • 587 citations

Noradrenergic mechanisms in stress and anxiety: I. preclinical studies

1996 • 583 citations

Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Comparison of stressors

1995 • 566 citations

Stress hormones and human memory function across the lifespan

2004 • 545 citations

Role of brain norepinephrine in the behavioral response to stress

2005 • 542 citations

Chronic stress alters synaptic terminal structure in hippocampus

1997 • 539 citations

Amygdala Is Critical for Stress-Induced Modulation of Hippocampal Long-Term Potentiation and Learning

2001 • 533 citations

Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats

1995 • 527 citations

Sex differences in dendritic atrophy of CA3 pyramidal neurons in response to chronic restraint stress

1997 • 522 citations

Selective Loss of Hippocampal Granule Cells in the Mature Rat Brain After Adrenalectomy

1989 • 520 citations

Neurotoxicity of Glucocorticoids in the Primate Brain

1994 • 519 citations

Sex Differences and Opposite Effects of Stress on Dendritic Spine Density in the Male Versus Female Hippocampus

2001 • 477 citations

The neurobiology of depression: inroads to treatment and new drug discovery.

2005 • 467 citations

Alterations in corticotropin-releasing factor-like immunoreactivity in discrete rat brain regions after acute and chronic stress

1986 • 466 citations

Social isolation delays the positive effects of running on adult neurogenesis

2006 • 452 citations

Brief Uncontrollable Stress Causes Dendritic Retraction in Infralimbic Cortex and Resistance to Fear Extinction in Mice

2006 • 450 citations

Recovery after chronic stress fails to reverse amygdaloid neuronal hypertrophy and enhanced anxiety-like behavior

2004 • 435 citations

Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress

2003 • 434 citations

Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice

2006 • 429 citations

Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: A meta-analysis

2005 • 403 citations

Corticosteroid effects in the brain: U-shape it

2006 • 393 citations

Rapid Glucocorticoid Signaling via Membrane-Associated Receptors

2006 • 386 citations

Effects of Glucocorticoids and Norepinephrine on the Excitability in the Hippocampus

1989 • 383 citations

Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders

2002 • 377 citations

Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly

2005 • 371 citations

Stress, cognitive impairment and cell adhesion molecules

2004 • 370 citations

Exposure to fox odor inhibits cell proliferation in the hippocampus of adult rats via an adrenal hormone‐dependent mechanism

2001 • 367 citations

Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis

2002 • 355 citations

Phenytoin prevents stress‐ and corticosterone‐induced atrophy of CA3 pyramidal neurons

1992 • 346 citations

Hippocampal Cytogenesis Correlates to Escitalopram-Mediated Recovery in a Chronic Mild Stress Rat Model of Depression

2006 • 345 citations

Chronic Social Stress Inhibits Cell Proliferation in the Adult Medial Prefrontal Cortex: Hemispheric Asymmetry and Reversal by Fluoxetine Treatment

2006 • 344 citations

Convergent Excitation of Dorsal Raphe Serotonin Neurons by Multiple Arousal Systems (Orexin/Hypocretin, Histamine and Noradrenaline)

2002 • 339 citations

Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system.

1993 • 335 citations

Mild, Short-term Stress Alters Dendritic Morphology in Rat Medial Prefrontal Cortex

2005 • 334 citations

Advances in Understanding Neuroendocrine Alterations in PTSD and Their Therapeutic Implications

2006 • 333 citations

Chronic social stress reduces dendritic arbors in CA3 of hippocampus and decreases binding to serotonin transporter sites

2000 • 331 citations

Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress

1999 • 329 citations

Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects

2006 • 327 citations

Effects of glucocorticoids on hippocampal long‐term potentiation

1993 • 320 citations

Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible

2003 • 315 citations

Effects of chronic stress on hippocampal long‐term potentiation

2002 • 312 citations

Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress

2005 • 310 citations

Blockade of CRF1 or V1b receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression

2003 • 309 citations

Insulin-like growth factor-I and neurogenesis in the adult mammalian brain

2002 • 307 citations

Corticotropin-Releasing Factor Requires CRF Binding Protein to Potentiate NMDA Receptors via CRF Receptor 2 in Dopamine Neurons

2003 • 297 citations

Exposure to Acute Stress Blocks the Induction of Long-Term Potentiation of the Amygdala–Prefrontal Cortex PathwayIn Vivo

2003 • 294 citations

Prolonged behavioral stress enhances synaptic connectivity in the basolateral amygdala

2006 • 292 citations

Stress-triggered activation of gene expression in catecholaminergic systems: dynamics of transcriptional events

2001 • 289 citations

Hippocampal Apoptosis in Major Depression Is a Minor Event and Absent from Subareas at Risk for Glucocorticoid Overexposure

2001 • 281 citations

Steroid Hormones and Excitability in the Mammalian Brain

1997 • 279 citations

Serotonin receptor binding in a colony model of chronic social stress

1995 • 278 citations

Corticosteroid Modulation of Hippocampal Potentials: Increased Effect with Aging

1989 • 274 citations

Morphological Correlates of Corticosteroid-Induced Changes in Prefrontal Cortex-Dependent Behaviors

2005 • 273 citations

Ethanol Augments GABAergic Transmission in the Central Amygdala via CRF1 Receptors

2004 • 269 citations

Opposing Crosstalk between Leptin and Glucocorticoids Rapidly Modulates Synaptic Excitation via Endocannabinoid Release

2006 • 265 citations

Stress Responsive Neurohormones in Depression and Anxiety

2003 • 260 citations

Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus

1998 • 260 citations

Multiple glucocorticoid receptor isoforms and mechanisms of post-translational modification

2006 • 258 citations

Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression

2003 • 258 citations

Chronic mild stress inhibits BDNF protein expression and CREB activation in the dentate gyrus but not in the hippocampus proper

2006 • 257 citations

Frequency-Dependent Noradrenergic Modulation of Long-Term Potentiation in the Hippocampus

1984 • 257 citations

Chronic stress-induced acceleration of electrophysiologic and morphometric biomarkers of hippocampal aging

1991 • 255 citations

Antidepressants Increase Glucocorticoid and Mineralocorticoid Receptor mRNA Expression in Rat Hippocampus in vivo

1992 • 255 citations

Telemetered Recording of Hormone Effects on Hippocampal Neurons

1971 • 254 citations

Biphasic Modulation of Hippocampal Plasticity by Behavioral Stress and Basolateral Amygdala Stimulation in the Rat

1999 • 253 citations

The Mineralocorticoid Receptor: A Journey Exploring Its Diversity and Specificity of Action

2005 • 252 citations

Chronic restraint or variable stresses differently affect the behavior, corticosterone secretion and body weight in rats

2006 • 251 citations

Chronic unpredictable stress impairs long‐term potentiation in rat hippocampal CA1 area and dentate gyrus in vitro

2003 • 251 citations

Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus

2001 • 247 citations

Sex Differences in Chronic Stress Effects on Memory in Rats

2002 • 245 citations

Chronic stress and social housing differentially affect neurogenesis in male and female rats

2004 • 241 citations

Hippocampal glucocorticoid receptor activation enhances voltage-dependent Ca2+ conductances: relevance to brain aging.

1992 • 241 citations

Glucocorticoids Enhance the Excitability of Principal Basolateral Amygdala Neurons

2007 • 237 citations

Chronic Antidepressants Reduce Depolarization-Evoked Glutamate Release and Protein Interactions Favoring Formation of SNARE Complex in Hippocampus

2005 • 232 citations

Stressful Experience and Learning Across the Lifespan

2005 • 228 citations

Mechanisms of Amygdala Modulation of Hippocampal Plasticity

2002 • 227 citations

Social factors and individual vulnerability to chronic stress exposure

2004 • 226 citations

Reduced cell proliferation in the dentate gyrusis not correlated with the development of learned helplessness

2003 • 222 citations

Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus

2005 • 216 citations

Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk‐1 protein expression

2005 • 215 citations

Corticotropin-Releasing Factor IncreasesIn VitroFiring Rates of Serotonergic Neurons in the Rat Dorsal Raphe Nucleus: Evidence for Activation of a Topographically Organized Mesolimbocortical Serotonergic System

2000 • 211 citations

What Is the Functional Significance of Chronic Stress-Induced CA3 Dendritic Retraction Within the Hippocampus?

2006 • 208 citations

Priming of Long-Term Potentiation in Mouse Hippocampus by Corticotropin-Releasing Factor and Acute Stress: Implications for Hippocampus-Dependent Learning

2002 • 207 citations

Recovery of the Hypothalamic-Pituitary-Adrenal Response to Stress

2000 • 207 citations

Adrenal Insufficiency and Colonic Inflammation after a Novel Chronic Psycho-Social Stress Paradigm in Mice: Implications and Mechanisms

2006 • 201 citations

Postweaning Development of Negative Feedback in the Pituitary-Adrenal System of the Rat

1973 • 200 citations

BDNF protects against stress‐induced impairments in spatial learning and memory and LTP

2004 • 198 citations

Requirement of Cannabinoid Receptor Type 1 for the Basal Modulation of Hypothalamic-Pituitary-Adrenal Axis Function

2006 • 198 citations

Effects of chronic stress on contextual fear conditioning and the hippocampal expression of the neural cell adhesion molecule, its polysialylation, and L1

2001 • 197 citations

Rapid reversal of stress induced loss of synapses in CA3 of rat hippocampus following water maze training

2003 • 197 citations

Stress suppresses and learning induces plasticity in CA3 of rat hippocampus: A three-dimensional ultrastructural study of thorny excrescences and their postsynaptic densities

2004 • 196 citations

Raised circulating corticosterone inhibits neuronal differentiation of progenitor cells in the adult hippocampus

2005 • 194 citations

Sex differences in cell proliferation, cell death and defensive behavior following acute predator odor stress in adult rats

2003 • 188 citations

Effects of chronic noise stress on spatial memory of rats in relation to neuronal dendritic alteration and free radical-imbalance in hippocampus and medial prefrontal cortex

2006 • 187 citations

Amygdalar Inactivation Blocks Stress-Induced Impairments in Hippocampal Long-Term Potentiation and Spatial Memory

2005 • 183 citations

Stressor-Specific Regulation of Distinct Brain-Derived Neurotrophic Factor Transcripts and Cyclic AMP Response Element-Binding Protein Expression in the Postnatal and Adult Rat Hippocampus

2006 • 183 citations

Fast glucocorticoid actions on brain: Back to the future

2005 • 182 citations

The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats

2002 • 181 citations

Brief Treatment With the Glucocorticoid Receptor Antagonist Mifepristone Normalises the Corticosterone‐Induced Reduction of Adult Hippocampal Neurogenesis

2006 • 180 citations

Restraint Increases Dopaminergic Burst Firing in Awake Rats

2005 • 177 citations

Dominance Hierarchy Influences Adult Neurogenesis in the Dentate Gyrus: Figure 1.

2004 • 177 citations

Regulation of Hippocampal Gene Expression Is Conserved in Two Species Subjected to Different Stressors and Antidepressant Treatments

2005 • 176 citations

Electroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment

2002 • 176 citations

Individual differences in anxiety trait are related to spatial learning abilities and hippocampal expression of mineralocorticoid receptors

2006 • 175 citations

Corticosterone Slowly Enhances Miniature Excitatory Postsynaptic Current Amplitude in Mice CA1 Hippocampal Cells

2005 • 172 citations

The corticoid environment: a determining factor for neural progenitors' survival in the adult hippocampus

2004 • 171 citations

Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers

2000 • 169 citations

Enhanced Long-Term Synaptic Depression in an Animal Model of Depression

2006 • 168 citations

Synergetic effects of quetiapine and venlafaxine in preventing the chronic restraint stress‐induced decrease in cell proliferation and BDNF expression in rat hippocampus

2006 • 166 citations

Timing is essential for rapid effects of corticosterone on synaptic potentiation in the mouse hippocampus

2006 • 159 citations

Chronic psychosocial stress enhances vasopressin, but not corticotropin-releasing factor, in the external zone of the median eminence of male rats: relationship to subordinate status.

1992 • 159 citations

Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume

2002 • 157 citations

Body weight gain and diurnal differences of corticosterone changes in response to acute and chronic stress in rats

2002 • 156 citations

Chronic psychosocial stress differentially affects apoptosis in hippocampal subregions and cortex of the adult tree shrew

2001 • 156 citations

Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus

2004 • 155 citations

Stress-Related Modulation of Hippocampal Long-Term Potentiation in Rats: Involvement of Adrenal Steroid Receptors

2003 • 153 citations

The selfish brain: competition for energy resources

2006 • 153 citations

Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus

2005 • 149 citations

Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons

1999 • 149 citations

Novelty‐elicited, Noradrenaline‐dependent Enhancement of Excitability in the Dentate Gyrus

1997 • 145 citations

Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system

1993 • 144 citations

Prominent Reduction in Pyramidal Neurons Density in the Orbitofrontal Cortex of Elderly Depressed Patients

2005 • 143 citations

Activity and plasticity in the CA1, the dentate gyrus, and the amygdala following controllable vs. uncontrollable water stress

2005 • 141 citations

Social Stress in Tree Shrews as an Animal Model of Depression: An Example of a Behavioral Model of a CNS Disorder

2005 • 138 citations

Corticosterone and stress reduce synaptic potentiation in mouse hippocampal slices with mild stimulation

2002 • 138 citations

Effect of chronic intermittent restraint stress on hippocampal expression of marker proteins for synaptic plasticity and progenitor cell proliferation in rats

2005 • 138 citations

Corticotropin-Releasing Factor and Urocortin I Modulate Excitatory Glutamatergic Synaptic Transmission

2004 • 137 citations

Stress Impairs α1A Adrenoceptor-Mediated Noradrenergic Facilitation of GABAergic Transmission in the Basolateral Amygdala

2003 • 135 citations

Rundown of N‐methyl‐D‐aspartate channels during whole‐cell recording in rat hippocampal neurons: role of Ca2+ and ATP.

1993 • 135 citations

Stress-induced spine loss in the medial amygdala is mediated by tissue-plasminogen activator

2006 • 134 citations

Chronic restraint stress induces changes in synapse morphology in stratum lacunosum-moleculare CA1 rat hippocampus: A stereological and three-dimensional ultrastructural study

2006 • 132 citations

Attenuating corticosterone levels on the day of memory assessment prevents chronic stress‐induced impairments in spatial memory

2006 • 131 citations

The biobehavioral consequences of psychogenic stress in a small, social primate (Callithrix jacchus jacchus)

1996 • 128 citations

Chronic mild stress decreases survival, but not proliferation, of new-born cells in adult rat hippocampus

2006 • 128 citations

Hippocampal homosynaptic long-term depression/depotentiation induced by adrenal steroids

1995 • 127 citations

Neuroendocrine and Immunocytochemical Demonstrations of Decreased Hypothalamo-Pituitary-Adrenal Axis Responsiveness to Restraint Stress after Long-Term Social Isolation¹

1998 • 126 citations

Corticosterone reduces the excitability of hippocampal pyramidal cells in vitro

1986 • 124 citations

Corticosteroid receptor-dependent modulation of calcium currents in rat hippocampal CA1 neurons

1994 • 124 citations

Selective Activation of Corticotropin-Releasing Factor-2 Receptors on Neurochemically Identified Neurons in the Rat Dorsal Raphe Nucleus Reveals Dual Actions

2004 • 123 citations

Chronic Cold Stress Reduces the Spontaneous Activity of Ventral Tegmental Dopamine Neurons

2001 • 122 citations

Glucocorticoid receptor-mediated inhibition by corticosterone of 5-ht1a autoreceptor functioning in the rat dorsal raphe nucleus

1995 • 122 citations

Glucocorticoids alter calcium conductances and calcium channel subunit expression in basolateral amygdala neurons

2002 • 122 citations

Synapse loss from chronically elevated glucocorticoids: Relationship to neuropil volume and cell number in hippocampal area CA3

2006 • 121 citations

Norepinephrine regulates long-term potentiation of both the population spike and dendritic EPSP in hippocampal dentate gyrus

1987 • 119 citations

Identification of genes regulated by chronic psychosocial stress and antidepressant treatment in the hippocampus

2004 • 118 citations

Hippocampal cell proliferation regulation by repeated stress and antidepressants

2006 • 117 citations

Involvement of the Endocannabinoid System in the Ability of Long-Term Tricyclic Antidepressant Treatment to Suppress Stress-Induced Activation of the Hypothalamic–Pituitary–Adrenal Axis

2006 • 116 citations

Effects of stress and long-term potentiation (LTP) on subsequent LTP and the theta burst response in the dentate gyrus

1994 • 115 citations

Chronic restraint stress and chronic corticosterone treatment modulate differentially the expression of molecules related to structural plasticity in the adult rat piriform cortex

2004 • 115 citations

Norepinephrine promotes long-term potentiation in the adult rat hippocampus in vitro

1999 • 112 citations

Isoproterenol potentiates synaptic transmission primarily by enhancing presynaptic calcium influx via P- and/or Q-type calcium channels in the rat amygdala

1996 • 111 citations

Effect of Chronic Stress on Synaptic Currents in Rat Hippocampal Dentate Gyrus Neurons

2003 • 110 citations

The stress-regulated protein M6a is a key modulator for neurite outgrowth and filopodium/spine formation

2005 • 108 citations

Long-Term Effects of Brief Acute Stress on Cellular Signaling and Hippocampal LTP

2006 • 108 citations

Differential actions of corticotropin releasing factor on basolateral and central amygdaloid neurones, in vitro.

1992 • 108 citations

Corticosteroid status influences the volume of the rat cingulate cortex – a magnetic resonance imaging study

2005 • 106 citations

5-HT1A autoreceptor desensitization by chronic ultramild stress in mice

1999 • 106 citations

Structural plasticity and tianeptine: cellular and molecular targets

2002 • 105 citations

Glucocorticoids Specifically Enhance L-Type Calcium Current Amplitude and Affect Calcium Channel Subunit Expression in the Mouse Hippocampus

2006 • 105 citations

Chronic stress induces opposite changes in the mRNA expression of the cell adhesion molecules NCAM and L1

2002 • 104 citations

Bidirectional modulation of long-term potentiation by novelty-exploration in rat dentate gyrus

2003 • 104 citations

Paradoxical effects of learning the Morris water maze on adult hippocampal neurogenesis in mice may be explained by a combination of stress and physical activity

2005 • 103 citations

Contrasting effects of neurohypophysial peptides on pyramidal and non-pyramidal neurones in the rat hippocampus

1984 • 103 citations

TheIn VivoTime Course for Elimination of Adrenalectomy-Induced Apoptotic Profiles from the Granule Cell Layer of the Rat Hippocampus

1997 • 102 citations

Differences between brain structures in nuclear translocation and DNA binding of the glucocorticoid receptor during stress and the circadian cycle

2004 • 102 citations

Chronic Cold Stress Alters Prefrontal Cortical Modulation of Amygdala Neuronal Activity in Rats

2005 • 100 citations

Noradrenaline Modulates GIutamate‐mediated Neurotransmission in the Rat Basolateral Amygdala In Vitro

1997 • 98 citations

Daily injections alter spine density in rat medial prefrontal cortex

2003 • 98 citations

Chronic psychosocial stress does not affect the number of pyramidal neurons in tree shrew hippocampus

1997 • 98 citations

Acute exposure to predator odor elicits a robust increase in corticosterone and a decrease in activity without altering proliferation in the adult rat hippocampus

2006 • 97 citations

Effects of mineralocorticoid and glucocorticoid receptors on long-term potentiation in the CA3 hippocampal field

1999 • 97 citations

GABAergic transmission in the rat paraventricular nucleus of the hypothalamus is suppressed by corticosterone and stress

2005 • 96 citations

SHORT COMMUNICATION Selective enhancement of spatial learning under chronic psychosocial stress

2002 • 96 citations

Blockade of glucocorticoid receptors rapidly restores hippocampal CA1 synaptic plasticity after exposure to chronic stress

2006 • 95 citations

Regulation of Editing and Expression of Glutamate α-Amino-Propionic-Acid (AMPA)/Kainate Receptors by Antidepressant Drugs

2006 • 95 citations

Chronic stress-induced changes in locus coeruleus neuronal activity

1990 • 95 citations

Chronic psychosocial stress enhances vasopressin, but not corticotropin- releasing factor, in the external zone of the median eminence of male rats: relationship to subordinate status

1992 • 95 citations

Bidirectional shift in the cornu ammonis 3 pyramidal dendritic organization following brief stress

2004 • 94 citations

Muscarinic and beta-adrenergic depression of the slow Ca2(+)-activated potassium conductance in hippocampal CA3 pyramidal cells is not mediated by a reduction of depolarization-induced cytosolic Ca2+ transients.

1990 • 91 citations

Social Subordinance in Wild Baboons Is Associated with Suppressed High Density Lipoprotein-Cholesterol Concentrations: The Possible Role of Chronic Social Stress*

1987 • 91 citations

Social stress-related behavior affects hippocampal cell proliferation in mice

2006 • 90 citations

Corticosterone shifts different forms of synaptic potentiation in opposite directions

2005 • 89 citations

Repeated handling, restraint, or chronic crowding impair the hypothalamic-pituitary-adrenocortical response to acute restraint stress.

2003 • 89 citations

Acute and chronic effects of corticosterone on 5-HT1A receptor-mediated autoinhibition in the rat dorsal raphe nucleus

2003 • 87 citations

Opposing regulation of the locus coeruleus by corticotropin-releasing factor and opioids

2001 • 87 citations

Restraint stress affects hippocampal cell proliferation differently in rats and mice

2004 • 86 citations

Acute stress increases calcium current amplitude in rat hippocampus: temporal changes in physiology and gene expression

2003 • 85 citations

Amygdala stimulation modulates hippocampal synaptic plasticity

2004 • 85 citations

Activity-stress induces atrophy of apical dendrites of hippocampal pyramidal neurons in male rats

1998 • 85 citations

α₂‐Adrenoreceptor activation inhibits LTP and LTD in the basolateral amygdala: involvement of G_i/o‐protein‐mediated modulation of Ca²⁺‐channels and inwardly rectifying K⁺‐channels in LTD

2003 • 80 citations

Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis.

2005 • 80 citations

Corticosteroid actions on amino acid-mediated transmission in rat CA1 hippocampal cells

1993 • 79 citations

Modulation of 5HT_1A Responsiveness in CA1 Pyramidal Neurons by in vivo Activation of Corticosteroid Receptors

1996 • 76 citations

Effects of corticosterone on excitatory amino acid responses in dopamine-sensitive neurons in the ventral tegmental area

1999 • 76 citations

Repeated Restraint Stress Alters Hippocampal Glutamate Uptake and Release in the Rat

2004 • 75 citations

Iontophoretic application of glucocorticoids inhibits identified neurones in the rat paraventricular nucleus

1988 • 71 citations

Spatial Performance and Corticosteroid Receptor Status in the 21‐Day Restraint Stress Paradigm

2004 • 70 citations

Effect of Chronic Administration of Selective Glucocorticoid Receptor Antagonists on the Rat Hypothalamic–Pituitary–Adrenocortical Axis

2002 • 70 citations

Recovery of hippocampal cell proliferation and BDNF levels, both of which are reduced by repeated restraint stress, is accelerated by chronic venlafaxine

2004 • 69 citations

Influence of corticotropin-releasing hormone on electrophysiological activity of locus coeruleus neurons

1996 • 68 citations

Neuronal Plasticity, Stress and Depression: Involvement of the Cytoskeletal Microtubular System?

2005 • 68 citations

The role of 5-HT1A receptors in the proliferation and survival of progenitor cells in the dentate gyrus of the adult hippocampus and their regulation by corticoids

2005 • 67 citations

Chronic cold exposure potentiates CRH-evoked increases in electrophysiologic activity of locus coeruleus neurons

2001 • 67 citations

Glucocorticoid receptors and β-adrenoceptors in basolateral amygdala modulate synaptic plasticity in hippocampal dentate gyrus, but not in area CA1

2006 • 67 citations

Chronic imipramine treatment partially reverses the long-term changes of hippocampal synaptic plasticity in socially stressed rats

2001 • 66 citations

Differential effects of stress on presynaptic and postsynaptic 5-hydroxytryptamine-1A receptors in the rat brain: an in vitro electrophysiological study

1999 • 64 citations

Chronic Exposure to Cold Stress Alters Electrophysiological Properties of Locus Coeruleus Neurons Recorded In Vitro

2003 • 63 citations

Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons

2003 • 62 citations

Bidirectional Modulation of Hippocampal Long-Term Potentiation under Stress and No-Stress Conditions in Basolateral Amygdala-Lesioned and Intact Rats

2005 • 59 citations

Site and time dependent effects of acute stress on hippocampal long-term potentiation in freely behaving rats

2003 • 57 citations

Acute cold stress leading to elevated corticosterone neither enhances synaptic efficacy nor impairs LTP in the dentate gyrus of freely moving rats

1998 • 53 citations

Microarray analysis of cultured human brain aggregates following cortisol exposure: Implications for cellular functions relevant to mood disorders

2006 • 53 citations

Distinct patterns of plasticity in prefrontal cortex neurons that encode slow and fast responses to stress

2006 • 48 citations

Chronic unpredictable stress alters gene expression in rat single dentate granule cells

2004 • 48 citations

Homeostatic maintenance in excitability of tree shrew hippocampal CA3 pyramidal neurons after chronic stress

2004 • 48 citations

Memory performance in tree shrews: effects of stressful experiences

1998 • 47 citations

Neuroendocrine and Immunocytochemical Demonstrations of Decreased Hypothalamo-Pituitary-Adrenal Axis Responsiveness to Restraint Stress after Long-Term Social Isolation

1998 • 45 citations

Brief RU 38486 Treatment Normalizes the Effects of Chronic Stress on Calcium Currents in Rat Hippocampal CA1 Neurons

2007 • 45 citations

Glucocorticoids Prolong Ca²⁺Transients in Hippocampal-Derived H19-7 Neurons by Repressing the Plasma Membrane Ca²⁺-ATPase-1

2002 • 44 citations

Agmatine increases proliferation of cultured hippocampal progenitor cells and hippocampal neurogenesis in chronically stressed mice

2006 • 44 citations

Neuropeptides in Anxiety Modulation

2005 • 41 citations

Effects of prolonged social isolation on responses of neurons in the bed nucleus of the stria terminalis, preoptic area, and hypothalamic paraventricular nucleus to stimulation of the medial amygdala

1995 • 41 citations

Synaptic transmission in the rat dentate gyrus after adrenalectomy

1998 • 41 citations

High-voltage-activated Ca2+ currents and the excitability of pyramidal neurons in the hippocampal CA3 subfield in rats depend on corticosterone and time of day

2001 • 40 citations

The effect of chronic treatment with antidepressant drugs on the corticosteroid receptor levels in the rat hippocampus.

1994 • 40 citations

Morphological and functional properties of rat dentate granule cells after adrenalectomy

2001 • 39 citations

β1 Adrenergic Receptor-Mediated Enhancement of Hippocampal CA3 Network Activity

2005 • 39 citations

Chronic non-invasive glucocorticoid administration decreases polysialylated neural cell adhesion molecule expression in the adult rat dentate gyrus

2004 • 38 citations

Differential Effects of Psychological and Immunological Challenge on the Hypothalamo‐Pituitary‐Adrenal Axis Function in Adjuvant‐induced Arthritis^a

1999 • 37 citations

Dissociation between apoptosis, neurogenesis, and synaptic potentiation in the dentate gyrus of adrenalectomized rats

2007 • 35 citations

Effect of Chronic Stress and Mifepristone Treatment on Voltage‐Dependent Ca²⁺ Currents in Rat Hippocampal Dentate Gyrus

2006 • 34 citations

The Activity of the Hypothalamo-Neurohypophysial System in Response to Acute Stressor Exposure: Neuroendocrine and Electrophysiological Observations

2004 • 34 citations

Prolonged corticosterone treatment alters the responsiveness of 5-HT 1A receptors to 8-OH-DPAT in rat CA1 hippocampal neurons

2002 • 33 citations

Hippocampal neurogenesis is not enhanced by lifelong reduction of glucocorticoid levels

2005 • 32 citations

The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates

2006 • 31 citations

Action of vasopressin on CA1 pyramidal neurons in rat hippocampal slices

1984 • 30 citations

Corticosteroids Influence the Action Potential Firing Pattern of Hippocampal Subfield CA3 Pyramidal Cells

1998 • 30 citations

Effects of vasopressin and related peptides on neurons of the rat lateral septum and ventral hippocampus

1999 • 29 citations

Chronic corticosterone treatment maintains synaptic activity of CA1 hippocampal pyramidal cells: Acute high corticosterone administration increases action potential number

1995 • 29 citations

Effects of arginine-vasopressin (AVP) on long-term potentiation in intact anesthetized rats

2003 • 26 citations

Expression Profiling Identifies the CRH/CRH-R1 System as a Modulator of Neurovascular Gene Activity

2007 • 25 citations

Modulation of the 5-hydroxytryptamine4 receptor-mediated response by short-term and long-term administration of corticosterone in rat CA1 hippocampal pyramidal neurons.

1995 • 25 citations

Effect of Corticosteroid Treatment In Vitro on Adrenalectomy‐Induced Impairment of Synaptic Transmission in the Rat Dentate Gyrus

2000 • 24 citations

Gene expression profiles associated with survival of individual rat dentate cells after endogenous corticosteroid deprivation

2004 • 19 citations

Effect of Adrenalectomy on Membrane Properties and Synaptic Potentials in Rat Dentate Granule Cells

2001 • 19 citations

Effects of vasopressin and involvement of receptor subtypes in the rat central amygdaloid nucleus in vitro

1997 • 17 citations

Effect of long-term elevated corticosteroid levels on field responses to synaptic stimulation, in the rat CA1 hippocampal area

1999 • 17 citations

Corticosteroid Effects on Serotonin Responses in Granule Cells of the Rat Dentate Gyrus

2001 • 17 citations

Effects of Chronic Stress and Phenytoin on the Long-term Potentiation (LTP) in Rat Hippocampal CA1 Region

2004 • 16 citations

Phenytoin reverses the chronic stress-induced impairment of memory consolidation for water maze training and depression of LTP in rat hippocampal CA1 region, but does not affect motor activity

2005 • 14 citations

Muscarinic Receptor Profiles of Mouse Brain Astrocytes in Culture Vary With Their Tissue Of Origin but Differ From Those of Neurons

1994 • 14 citations

Glucocorticoids Prolong Ca2+ Transients in Hippocampal-Derived H19-7 Neurons by Repressing the Plasma Membrane Ca2+-ATPase-1

2002 • 13 citations

Endocannabinoids Link Rapid, Membrane-Mediated Corticosteroid Actions to Behavior

2007 • 9 citations

Reply: Clinical and Biological Effects of Mifepristone Treatment for Psychotic Treatment

2006 • 6 citations