On the Interactions of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Sleep: Normal HPA Axis Activity and Circadian Rhythm, Exemplary Sleep Disorders

Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite

2004 • 2,291 citations

Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat

1972 • 2,054 citations

The sleep switch: hypothalamic control of sleep and wakefulness

2001 • 1,609 citations

Free Cortisol Levels after Awakening: A Reliable Biological Marker for the Assessment of Adrenocortical Activity

1997 • 1,404 citations

The role of corticotropin-releasing factor in depression and anxiety disorders

1999 • 1,371 citations

Sleep Apnea and Daytime Sleepiness and Fatigue: Relation to Visceral Obesity, Insulin Resistance, and Hypercytokinemia

2000 • 1,127 citations

Leptin Levels Are Dependent on Sleep Duration: Relationships with Sympathovagal Balance, Carbohydrate Regulation, Cortisol, and Thyrotropin

2004 • 967 citations

Normal Human Sleep: An Overview

2005 • 932 citations

Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome

2004 • 816 citations

Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications

2001 • 774 citations

Effect of SCN lesions on sleep in squirrel monkeys: evidence for opponent processes in sleep-wake regulation

1993 • 655 citations

Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: Relation to hypercortisolism and corticotropin-releasing hormone

2000 • 559 citations

Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression

2002 • 513 citations

Human Growth Hormone Release: Relation to Slow-Wave Sleep and Sleep-Waking Cycles

1969 • 398 citations

Plasma Leptin Levels Are Increased in Survivors of Acute Sepsis: Associated Loss of Diurnal Rhythm in Cortisol and Leptin Secretion

1998 • 393 citations

The biological clock tunes the organs of the body: timing by hormones and the autonomic nervous system

2003 • 389 citations

Chronic insomnia and activity of the stress system

1998 • 384 citations

Sleep, the hypothalamic–pituitary–adrenal axis, and cytokines: multiple interactions and disturbances in sleep disorders

2002 • 376 citations

Sleep Apnea and Daytime Sleepiness and Fatigue: Relation to Visceral Obesity, Insulin Resistance, and Hypercytokinemia

2000 • 365 citations

Diurnal and Ultradian Dynamics of Serum Adiponectin in Healthy Men: Comparison with Leptin, Circulating Soluble Leptin Receptor, and Cortisol Patterns

2003 • 357 citations

Effects of Corticotropin-Releasing Factor and Growth Hormone-Releasing Factor on Sleep and Activity in Rats

1986 • 313 citations

Neuroendocrine Dysfunction in Sleep Apnea: Reversal by Continuous Positive Airways Pressure Therapy*

1989 • 290 citations

Sleep and the hypothalamo–pituitary–adrenocortical system

2002 • 288 citations

Resistant Hypertension, Obesity, Sleep Apnea, and Aldosterone

2004 • 280 citations

Leptin and ghrelin levels in patients with obstructive sleep apnoea: effect of CPAP treatment

2003 • 279 citations

Monitoring and Staging Human Sleep

2005 • 278 citations

Rapid Reversal of Psychotic Depression Using Mifepristone

2001 • 274 citations

Regulation of Sleep and Circadian Rhythms

1999 • 273 citations

Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: Implications for the circadian control of behavioural state

2004 • 266 citations

Interactions between evening and nocturnal cortisol secretion and sleep parameters in patients with severe chronic primary insomnia

2002 • 263 citations

Cortisol Secretion Is Inhibited during Sleep in Normal Man*

1983 • 263 citations

Sleep disruption alters nocturnal ACTH and cortisol secretory patterns

1991 • 261 citations

Effects of Intravenous Corticotropin-Releasing Hormone upon Sleep-Related Growth Hormone Surge and Sleep EEG in Man

1988 • 261 citations

Activation of the locus coeruleus noradrenergic system by intracoerulear microinfusion of corticotropin-releasing factor: effects on discharge rate, cortical norepinephrine levels and cortical electroencephalographic activity.

1997 • 240 citations

Effects of Growth Hormone-Releasing Hormone and Somatostatin on Sleep EEG and Nocturnal Hormone Secretion in Male Controls

1992 • 211 citations

Nocturnal Cortisol Release in Relation to Sleep Structure

1992 • 188 citations

Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications

2001 • 181 citations

Influences of Corticotropin-Releasing Hormone, Adrenocorticotropin, and Cortisol on Sleep in Normal Man*

1989 • 171 citations

The significance of sleep onset and slow wave sleep for nocturnal release of growth hormone (GH) and cortisol

1988 • 166 citations

Pituitary reactivity, androgens and catecholamines in obstructive sleep apnoea. Effects of continuous positive airway pressure treatment (CPAP)

1999 • 164 citations

Gluco- and antimineralocorticoid effects on human sleep: a role of central corticosteroid receptors

1991 • 163 citations

Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropinreleasing hormone

2000 • 160 citations

Evidence for Mineralocorticoid Receptor Facilitation of Glucocorticoid Receptor-Dependent Regulation of Hypothalamic-Pituitary-Adrenal Axis Activity*

1998 • 155 citations

Cerebrospinal Fluid Immunoreactive Cortieotropin-Releasing Hormone and Adrenocorticotropin Secretion in Cushing's Disease and Major Depression: Potential Clinical Implications

1991 • 146 citations

Adrenal steroid receptor activation in rat brain and pituitary following dexamethasone: Implications for the dexamethasone suppression test

1992 • 139 citations

Acute Effect of a Glucocorticoid on Normal Human Sleep

1972 • 133 citations

Middle-Aged Men Show Higher Sensitivity of Sleep to the Arousing Effects of Corticotropin-Releasing Hormone Than Young Men: Clinical Implications

2001 • 127 citations

Treatment with the CRH1-receptor-antagonist R121919 improves sleep-EEG in patients with depression

2003 • 126 citations

Neuroendocrine dysregulation in primary insomnia.

2001 • 123 citations

Convergence of circadian and sleep regulatory mechanisms on hypocretin-1

2004 • 118 citations

The Renin-Angiotensin-Aldosterone system in patients with depression compared to controls – a sleep endocrine study

2003 • 117 citations

Leptin

2003 • 113 citations

Night-time plasma cortisol secretion is associated with specific sleep stages

1986 • 110 citations

The effect of dawn simulation on the cortisol response to awakening in healthy participants

2003 • 108 citations

Corticotropin-Releasing Hormone and Arginine Vasopressin Gene Transcription in the Hypothalamic Paraventricular Nucleus of Unstressed Rats: Daily Rhythms and Their Interactions with Corticosterone

2003 • 103 citations

Plasma Leptin Levels Are Increased in Survivors of Acute Sepsis: Associated Loss of Diurnal Rhythm in Cortisol and Leptin Secretion

1998 • 103 citations

Endocrine and other biological rhythms

2001 • 101 citations

Corticotropin-releasing hormone involvement in stressor-induced alterations in sleep and in the regulation of waking

1995 • 98 citations

Nocturnal adrenocorticotropin and cortisol secretion depends on sleep duration and decreases in association with spontaneous awakening in the morning.

1992 • 97 citations

Corticotropin-releasing hormone (CRH) as a regulator of waking

2001 • 93 citations

Monitoring and Staging Human Sleep

2011 • 92 citations

Corticotropic-releasing hormone and serotonin interact in the human brainstem: behavioral implications

1999 • 87 citations

Effects of Hormones on Sleep

1998 • 85 citations

Long-term regulation of locus ceruleus sensitivity to corticotropin-releasing factor by swim stress.

1999 • 84 citations

The Dexamethasone Suppression Test as a Discriminator among Subtypes of Psychotic Patients

1982 • 84 citations

Getting closer to affective disorders: the role of CRH receptor systems

2004 • 83 citations

Glucocorticoid Replacement Is Permissive for Rapid Eye Movement Sleep and Sleep Consolidation in Patients with Adrenal Insufficiency1

2000 • 82 citations

Sleep and endocrine changes after intranasal administration of growth hormone-releasing hormone in young and aged humans

1999 • 79 citations

Corticotropin-releasing hormone-induced adrenocorticotropin and cortisol secretion depends on sleep and wakefulness.

1993 • 76 citations

Delta Sleep Response to Metyrapone in Post-Traumatic Stress Disorder

2003 • 74 citations

Further definition of the effect of corticosterone on the sleep–wake pattern in the male rat

2001 • 72 citations

Role of the hypothalamic pituitary adrenal axis in the control of the response to stress and infection

2000 • 70 citations

Effects of adrenalectomy and subsequent corticosterone replacement on rat sleep state and EEG power spectra

1998 • 66 citations

Acute Withdrawal of Nasal CPAP in Obstructive Sleep Apnea Does Not Cause a Rise in Stress Hormones

1996 • 66 citations

Hypothalamic-pituitary-adrenal axis in the night eating syndrome

2002 • 60 citations

Acute Cortisol Administration Promotes Sleep Intensity in Man

2003 • 59 citations

Depression-like changes of the sleep-EEG during high dose corticosteroid treatment in patients with multiple sclerosis

2003 • 58 citations

Evidence for Mineralocorticoid Receptor Facilitation of Glucocorticoid Receptor-Dependent Regulation of Hypothalamic-Pituitary-Adrenal Axis Activity

1998 • 58 citations

Obstructive Sleep Apnoea and Depression — Diagnostic and Treatment Implications

1992 • 49 citations

Regulation of the Stress Response by Corticotropin-Releasing Factor Receptors

2000 • 48 citations

Middle-Aged Men Show Higher Sensitivity of Sleep to the Arousing Effects of Corticotropin-Releasing Hormone Than Young Men: Clinical Implications

2001 • 43 citations

Acute Delirium as a Manifestation of Obstructive Sleep Apnea Syndrome

1998 • 41 citations

Changes in Sleep‐Endocrine Activity after Growth Hormone‐Releasing Hormone Depend on Time of Administration

1997 • 41 citations

Locomotor‐dependent and ‐independent components to hypocretin‐1 (orexin A) regulation in sleep–wake consolidating monkeys

2004 • 40 citations

Nocturnal adrenocorticotropin and cortisol secretion depends on sleep duration and decreases in association with spontaneous awakening in the morning

1992 • 37 citations

Corticotropin-releasing hormone-induced adrenocorticotropin and cortisol secretion depends on sleep and wakefulness

1993 • 36 citations

Glucocorticoid Replacement Is Permissive for Rapid Eye Movement Sleep and Sleep Consolidation in Patients with Adrenal Insufficiency

2000 • 34 citations

Insulin Resistance and Obstructive Sleep Apnea: Is Increased Sympathetic Stimulation the Link?

2003 • 34 citations

Entrainment of Nocturnal Pituitary-Adrenocortical Activity to Sleep Processes in Man — A Hypothesis

2009 • 33 citations

Paranoid psychosis and sleep apnea syndrome

1980 • 32 citations

Psychosis in Sleep Apnoea

1989 • 23 citations

Surgical treatment of sleep-apnea-associated psychosis.

1981 • 22 citations

Interactions of Leptin, GH, and Cortisol in Normal Children

2003 • 20 citations

Circadian and Sleep Control of Hormonal Secretions

1999 • 4 citations

Deleted Work

1955 • 0 citations

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