Transcriptional Regulation of the Membrane-associated Prostaglandin E2 Synthase Gene

Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology

2001 • 3,629 citations

The “initiator” as a transcription control element

1989 • 1,597 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Prostaglandins as modulators of immunity

2002 • 1,167 citations

The Sp-family of transcription factors

1999 • 1,098 citations

Sp1 and krüppel‐like factor family of transcription factors in cell growth regulation and cancer

2001 • 1,026 citations

Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

1999 • 990 citations

Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2

2000 • 945 citations

A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences.

1988 • 733 citations

Molecular Identification of Cytosolic Prostaglandin E2 Synthase That Is Functionally Coupled with Cyclooxygenase-1 in Immediate Prostaglandin E2Biosynthesis

2000 • 700 citations

Hypoxia Induces Cyclooxygenase-2 via the NF-κB p65 Transcription Factor in Human Vascular Endothelial Cells

1997 • 673 citations

Transcriptional Roles of Nuclear Factor κB and Nuclear Factor-Interleukin-6 in the Tumor Necrosis Factor α-Dependent Induction of Cyclooxygenase-2 in MC3T3-E1 Cells

1995 • 657 citations

Why there are two cyclooxygenase isozymes

2001 • 612 citations

Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells.

1988 • 580 citations

Regulatory Functions of Phospholipase A2

1997 • 551 citations

Coexpression of Microsomal-Type Prostaglandin E Synthase with Cyclooxygenase-2 in Brain Endothelial Cells of Rats during Endotoxin-Induced Fever

2001 • 370 citations

Microsomal Prostaglandin E Synthase Is Regulated by Proinflammatory Cytokines and Glucocorticoids in Primary Rheumatoid Synovial Cells

2001 • 272 citations

Cloning, Expression, and Up-regulation of Inducible Rat Prostaglandin E Synthase during Lipopolysaccharide-induced Pyresis and Adjuvant-induced Arthritis

2001 • 244 citations

Coordinate up‐ and down‐regulation of glutathione‐dependent prostaglandin E synthase and cyclooxygenase‐2 in A549 cells

2000 • 215 citations

Transcriptional Regulation of Cyclooxygenase-2 in Mouse Skin Carcinoma Cells

1998 • 197 citations

The role of prostaglandins in bone in vivo

1990 • 189 citations

Transcriptional Role of the Nuclear Factor κB Site in the Induction by Lipopolysaccharide and Suppression by Dexamethasone of Cyclooxygenase-2 in U937 Cells

1998 • 185 citations

Segregated Coupling of Phospholipases A2, Cyclooxygenases, and Terminal Prostanoid Synthases in Different Phases of Prostanoid Biosynthesis in Rat Peritoneal Macrophages

1998 • 179 citations

NF-κB and AP-1 Activation by Nitric Oxide Attenuated Apoptotic Cell Death in RAW 264.7 Macrophages

1999 • 157 citations

The role of early growth response gene 1 (egr-1) in regulation of the immune response

1996 • 151 citations

Up-regulation of Prostaglandin E2 Synthesis by Interleukin-1β in Human Orbital Fibroblasts Involves Coordinate Induction of Prostaglandin-Endoperoxide H Synthase-2 and Glutathione-dependent Prostaglandin E2 Synthase Expression

2002 • 151 citations

Stress-induced Stimulation of Early Growth Response Gene-1 by p38/Stress-activated Protein Kinase 2 Is Mediated by a cAMP-responsive Promoter Element in a MAPKAP Kinase 2-independent Manner

1999 • 126 citations

Human glutathione dependent prostaglandin E synthase: gene structure and regulation

2000 • 117 citations

Human Vascular Smooth Muscle Cells but Not Endothelial Cells Express Prostaglandin E Synthase

2000 • 113 citations

Molecular Cloning and Induction of Bovine Prostaglandin E Synthase by Gonadotropins in Ovarian Follicles Prior to Ovulationin Vivo

2001 • 100 citations

Transcription Suppression of Thromboxane Receptor Gene by Peroxisome Proliferator-activated Receptor-γ via an Interaction with Sp1 in Vascular Smooth Muscle Cells

2002 • 90 citations

Transforming Growth Factor-α Enhances Cyclin D1 Transcription through the Binding of Early Growth Response Protein to a cis-Regulatory Element in the Cyclin D1 Promoter

1997 • 88 citations

Ionizing Radiation-inducible Apoptosis in the Absence of p53 Linked to Transcription Factor EGR-1

1997 • 86 citations

Functional Analysis of the Proximal 5′-Flanking Region of the N-Methyl-D-aspartate Receptor Subunit Gene, NMDAR1

1995 • 83 citations

Major roles of prostanoid receptors IP and EP3 in endotoxin-induced enhancement of pain perception

2001 • 77 citations

Expression of prostaglandin E synthase mRNA is induced in beta-amyloid treated rat astrocytes

2000 • 60 citations

Induction of cyclooxygenase-2 causes an enhancement of writhing response in mice

1998 • 50 citations

Early growth responsive‐1‐dependent manganese superoxide dismutase gene transcription mediated by platelet‐derived growth factor

2001 • 41 citations

The Transcription Factor Sp1 Regulates the Myeloid-specific Expression of the Human Hematopoietic Cell Kinase (HCK) Gene through Binding to Two Adjacent GC Boxes within the HCK Promoter-Proximal Region

1998 • 38 citations

Acceleration of Thrombomodulin Gene Transcription by Retinoic Acid

2001 • 35 citations

Functional Characterization of the 5'-Regulatory Region of the Human Thrombomodulin Gene1

1993 • 33 citations

Agonist stimulation of B₁ and B₂ kinin receptors causes activation of the MAP kinase signaling pathway, resulting in the translocation of AP‐1 in HEK 293 cells

1998 • 25 citations

The Exon Structure of the Human MAGP-2 Gene

1998 • 14 citations

Cloning and characterization of 5′-flanking region of mouse prostacyclin synthase gene

2000 • 3 citations