Cloning and characterization of 5′-flanking region of mouse prostacyclin synthase gene

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin.

1978 • 1,559 citations

Prostaglandins and Thromboxanes

1978 • 1,310 citations

Molecular cloning (2nd Ed)

1989 • 1,191 citations

An Imbalance between the Excretion of Thromboxane and Prostacyclin Metabolites in Pulmonary Hypertension

1992 • 1,180 citations

Prostacyclin Synthase Expression Is Decreased in Lungs from Patients with Severe Pulmonary Hypertension

1999 • 788 citations

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

1990 • 677 citations

A tale of three fingers: the family of mammalian Sp/XKLF transcription factors

1999 • 607 citations

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

1992 • 577 citations

A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo.

1995 • 490 citations

Pharmacodynamic profile of prostacyclin

1995 • 291 citations

Characterization of the Human Endothelial Nitric-oxide Synthase Promoter

1999 • 212 citations

Molecular Cloning and Expression of Human Prostacyclin Synthase

1994 • 111 citations

Human Prostacyclin Synthase Gene and Hypertension

1999 • 75 citations

Overexpression of Prostacyclin Synthase Inhibits Growth of Vascular Smooth Muscle Cells

1995 • 74 citations

Human Gene Encoding Prostacyclin Synthase (PTGIS): Genomic Organization, Chromosomal Localization, and Promoter Activity

1996 • 74 citations

Gene Transfer of Human Prostacyclin Synthase Prevents Neointimal Formation After Carotid Balloon Injury in Rats

1999 • 73 citations

Prostacyclin and thromboxane synthases

1995 • 70 citations

Alteration in prostacyclin and prostaglandin E2 production. Correlation with changes in human aortic atherosclerotic disease.

1984 • 69 citations

Involvement of Two Sp1 Elements in Basal Endothelial Prostaglandin H Synthase-1 Promoter Activity

1997 • 68 citations

GC Factor 2 Represses Platelet-Derived Growth Factor A-Chain Gene Transcription and Is Itself Induced by Arterial Injury

1999 • 59 citations

The regional distribution and cellular localization of mRNA encoding rat prostacyclin synthase.

1997 • 47 citations

Decreased prostaglandin production in cultured smooth muscle cells from atherosclerotic rabbit aorta

1982 • 43 citations

A Sp1 Binding Site in the GC-Rich Region Is Essential for a Core Promoter Activity of the Human Endothelial Nitric Oxide Synthase Gene

1995 • 37 citations

Organization of the Human Prostacyclin Synthase Gene

1996 • 29 citations

Inverse gene expression of prostacyclin and thromboxane synthases in resident and activated peritoneal macrophages¹

1997 • 22 citations

Organization of the Gene Encoding Human Prostacyclin Synthase

1996 • 21 citations

Genomic Organization, Chromosomal Localization, and Expression of the Murine Thromboxane Synthase Gene (Tbxas1)

1997 • 19 citations

Sp1 Dependence of Natriuretic Peptide Receptor A Gene Transcription in Rat Aortic Smooth Muscle Cells¹

1999 • 19 citations