A cellular and functional split in the DRw8 haplotype is due to a single amino acid replacement (DR ? ser 57- asp 57 )

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

High-Efficiency Cloning of Full-Length cDNA

1982 • 1,309 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

Transfer of Proteins Across Membranes

1981 • 894 citations

High-efficiency cloning of full-length cDNA.

1982 • 763 citations

A Molecular Basis for MHC Class II—Associated Autoimmunity

1988 • 707 citations

Molecular diversity of HLA-DR4 haplotypes.

1986 • 385 citations

An Improved Method for Isolation of H-2 and Ia Alloantigens with Immunoprecipitation Induced by Protein A-Bearing Staphylococci

1976 • 351 citations

The nucleotide sequence of the chick cytoplasmic β-actin gene

1983 • 336 citations

Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens

1982 • 308 citations

Polymorphism of human Ia antigens: gene conversion between two DR β loci results in a new HLA-D/DR specificity

1986 • 292 citations

The structure of a mutant H–2 gene suggests that the generation of polymorphism in H–2 genes may occur by gene conversion-like events

1983 • 277 citations

Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.

1983 • 271 citations

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

1984 • 232 citations

Allelic variation in the DR subregion of the human major histocompatibility complex.

1987 • 220 citations

Histocompatibility Testing

2000 • 219 citations

Class II genes of the human major histocompatibility complex. Organization and evolutionary relationship of the DR beta genes.

1987 • 186 citations

Sequence polymorphism of HLA DRβ1 alleles relating to T-cell-recognized determinants

1985 • 183 citations

Nucleotide sequence of mutant I-Aβbm12 gene is evidence for genetic exchange between mouse immune response genes

1984 • 178 citations

Linkage map of three HLA-DR beta-chain genes: evidence for a recent duplication event.

1985 • 155 citations

HLA-DR beta genes vary in number between different DR specificities, whereas the number of DQ beta genes is constant.

1985 • 154 citations

Characterization of an HLA DR beta pseudogene.

1985 • 138 citations

High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast.

1985 • 115 citations

Class II genes of the human major histocompatibility complex. Comparisons of the DQ and DX alpha and beta genes.

1987 • 103 citations

Genetics and Expression of Mouse Ia Antigens

1985 • 99 citations

Reactivity of a Rabbit Antiserum against Highly Purified HLA‐DR Antigens

1978 • 76 citations

Structural comparison of the genes of two HLA-DR supertypic groups: The loci encoding DRw52 and DRw53 are not truly allelic

1987 • 73 citations

The Eb beta gene may have acted as the donor gene in a gene conversion-like event generating the Abm 12 beta mutant.

1984 • 62 citations

I-A-restricted T cell antigen recognition. Analysis of the roles of A alpha and A beta using DNA-mediated gene transfer.

1986 • 56 citations

Constitutive and induced expression of the individual HLA-DR beta and alpha chain loci in different cell types

1988 • 53 citations

Molecular mechanisms for gene conversion in higher cells

1986 • 51 citations

Oligonucleotide genotyping shows that alleles at the HLA-DR ? III locus of the DRw52 supertypic group segregate independently of known DR or Dw specificities

1987 • 45 citations

Characterization of two distinct DR beta chain alleles at the beta III locus of the DR5 haplotype: beta III alleles are highly conserved.

1986 • 44 citations

Constitutive and induced expression of the individual HLA-DR beta and alpha chain loci in different cell types.

1987 • 44 citations

A directional process of gene conversion is expected to yield dynamic polymorphism associated with stability of alternative alleles in class I histocompatibility antigens gene family

1983 • 41 citations

Analysis of the HLA-DRw8 haplotype: Recognition by HTC typing of three distinct antigen complexes in Caucasians, Native Americans, and Orientals

1983 • 38 citations

Implications of the invariant gamma-chain on the intracellular transport of class II histocompatibility antigens.

1985 • 38 citations

Definition of HLA-D with HTC

1984 • 37 citations

Functional polymorphism of each of the two HLA-DR beta chain loci demonstrated with antigen-specific DR3- and DRw52-restricted T cell clones.

1988 • 27 citations

Electrophoretic variation between class II molecules expressed on HLA-DRw8 homozygous typing cells reveals multiple distinct haplotypes

1985 • 27 citations

Cell-free synthesis and processing of the heavy and light chains of HLA-DR antigens.

1980 • 26 citations

The single DR ? gene of the DRw8 haplotype is closely related to the DR ? 3III gene encoding DRw52

1988 • 22 citations

Antigen Report: HLA-DRw8

1984 • 15 citations

Functional subdivision of HLA-DRw8 with influenza-specific cloned cell lines

1985 • 8 citations

Definition of DW8.2 by primary and secondary mixed lymphocyte cultures

1985 • 7 citations

Structure of Human Class II Antigens Expressed by a Homozygous Lymphoblastoid B Cell Line

1986 • 6 citations

DQ Wa gives rise to a DQβ restriction fragment pattern indistinguishable from that of the DQw3.2 sub‐type Of DQw3

1988 • 4 citations

The two-dimensional migration pattern of the single HLA-DR beta chain expressed in DRw8 haplotypes is not fully predictive of its activity in antigen presentation

1988 • 3 citations