High-Efficiency Cloning of Full-Length cDNA

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA

1972 • 2,842 citations

Preparative and analytical purification of DNA from agarose.

1979 • 1,585 citations

Primary structure, gene organization and polypeptide expression of poliovirus RNA

1981 • 897 citations

A complete immunoglobulin gene is created by somatic recombination.

1978 • 610 citations

A bacterial clone synthesizing proinsulin.

1978 • 515 citations

Stimulation by Cyclic Adenosine Monophosphate of Plasmid Deoxyribonucleic Acid Replication and Catabolite Repression of the Plasmid Deoxyribonucleic Acid-Protein Relaxation Complex

1973 • 505 citations

The primary structure of rabbit β-globin mRNA as determined from cloned DNA

1977 • 428 citations

Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase

1978 • 426 citations

The rabbit β-globin gene contains a large insert in the coding sequence

1977 • 422 citations

Terminal labeling and addition of homopolymer tracts to duplex DNA fragments by terminal deoxynudeotidyl transferase

1976 • 416 citations

Ovalbumin gene is split in chicken DNA

1977 • 396 citations

Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

1981 • 374 citations

5′-Terminal sequences of eucaryotic mRNA can be cloned with high efficiency

1981 • 367 citations

Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome

1979 • 355 citations

Enzymatic in vitro synthesis of globin genes

1976 • 343 citations

Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

1978 • 254 citations

The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor.

1978 • 242 citations

Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells

1976 • 237 citations

Isolation and characterization of a cloned rat insulin gene

1979 • 229 citations

Complete intergenic and flanking gene sequences from the genome of vesicular stomatitis virus

1980 • 228 citations

The reverse transcriptase

1977 • 194 citations

Terminal labeling and addition of homopolymer tracts to duplex DNA fragments by terminal deoxynucleotidyl transferase

1976 • 191 citations

Nucleotide sequence analysis of the leader segments in a cloned copy of adenovirus 2 fiber mRNA

1979 • 184 citations

The primary sequence of rabbit α-globin mRNA

1978 • 174 citations

Insertion of a rabbit β-globin gene sequence into an E.coli plasmid

1975 • 164 citations

Mechanism of Action of Ribonuclease H Isolated from Avian Myeloblastosis Virus and Escherichia coli

1973 • 136 citations

Bacterial cloning of plasmids carrying copies of rabbit globin messenger RNA

1976 • 107 citations

N-(Phosphonacetyl)-L-aspartate-resistant hamster cells overaccumulate a single mRNA coding for the multifunctional protein that catalyzes the first steps of UMP synthesis.

1979 • 95 citations

Construction and identification by positive hybridization-translation of a bacterial plasmid containing a rat growth hormone structural gene sequence

1978 • 93 citations

Enzymatic Breakage and Joining of Deoxyribonucleic Acid

1971 • 77 citations

A cautionary note on the use of certain restriction endonucleases with methylated substrates

1980 • 74 citations

The Separation and Identification of α- and β-Globin Messenger Ribonucleic Acids

1974 • 60 citations

The chick ovomucoid gene contains at least six intervening sequences

1979 • 47 citations

Integration of synthetic globin genes into an E. coli plasmid

1976 • 46 citations

Cleavage of DNA.RNA hybrids by Type II restriction enzymes

1980 • 41 citations

Cloning of Double-Stranded cDNA

1979 • 34 citations

The influenza virus haemagglutinin gene: cloning and characterisation of a double-stranded DNA copy

1979 • 30 citations

Cloned copy of the haemagglutinin gene codes for human influenza antigenic determinants in E. coli

1981 • 28 citations