Structure of Human Class II Antigens Expressed by a Homozygous Lymphoblastoid B Cell Line

Prediction of protein conformation

1974 • 3,327 citations

Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins

1974 • 2,173 citations

The Hydrophobic Effect and the Organization of Living Matter

1978 • 928 citations

Membrane Structure: Some General Principles

1973 • 825 citations

The H-2 Major Histocompatibility Complex and the/Immune Response Region: Genetic Variation, Function, and Organization

1975 • 774 citations

Isolation and Properties of a Low Molecular Weight β2-Globulin Occurring in Human Biological Fluids

1968 • 733 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

Role of MHC Gene Products in Immune Regulation

1981 • 705 citations

Genetic Control of Specific Immune Responses

1969 • 681 citations

The class II molecules of the human and murine major histocompatibility complex

1984 • 664 citations

Histocompatibility Testing 1984

1985 • 535 citations

The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains

1984 • 507 citations

T cell antigen receptors and the immunoglobulin supergene family

1985 • 453 citations

Genes of the Major Histocompatibility Complex of the Mouse

1983 • 445 citations

The Major Histocompatibility Complex of the Mouse

1979 • 423 citations

Differential function of major histocompatibility complex antigens in T-lymphocyte activation

1976 • 419 citations

β ₂ -Microglobulin—A Free Immunoglobulin Domain

1972 • 387 citations

Three-Dimensional Structure of the Fab′ Fragment of a Human Immunoglobulin at 2.8-Å Resolution

1973 • 381 citations

Evidence for a new segregant series of B cell antigens that are encoded in the HLA-D region and that stimulate secondary allogenic proliferative and cytotoxic responses.

1980 • 348 citations

Prediction of chain turns in globular proteins on a hydrophobic basis

1978 • 334 citations

Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens.

1982 • 320 citations

The β2-microglobulin gene is on chromosome 15 and not in the HL-A region

1975 • 274 citations

Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.

1983 • 271 citations

Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes

1984 • 261 citations

HLA‐DR Antigens: Structure, Separation of Subpopulations, Gene Cloning and Function

1982 • 258 citations

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

1984 • 232 citations

Isolation and immunologic characterization of a human. B-lymphocyte-specific, cell surface antigen.

1976 • 211 citations

Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains.

1984 • 190 citations

Cysteines in the transmembrane region of major histocompatibility complex antigens are fatty acylated via thioester bonds.

1984 • 189 citations

Alpha chain of HLA-DR transplantation antigens is a member of the same protein superfamily as the immunoglobulins

1982 • 168 citations

Exon-intron organization and complete nucleotide sequence of a human major histocompatibility antigen DC beta gene.

1983 • 162 citations

cDNA clone for the heavy chain of the human B cell alloantigen DC1: strong sequence homology to the HLA-DR heavy chain.

1982 • 162 citations

Sequence of an HLA-DR α-chain cDNA clone and intron-exon organization of the corresponding gene

1982 • 153 citations

A program for prediction of protein secondary structure from nucleotide sequence data: application to histocompatibility antigens

1984 • 150 citations

Characterization of an HLA DR beta pseudogene.

1985 • 138 citations

The Major Histocompatibility System in Man and Animals.

1979 • 136 citations

Human Antigen and Enzyme Markers in Man-Chinese Hamster Somatic Cell Hybrids: Evidence for Synteny Between the HL-A, PGM ₃ , ME ₁ , and IPO-B Loci

1974 • 135 citations

Structure and nucleotide sequence of the heavy chain gene of HLA-DR.

1983 • 132 citations

Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta.

1984 • 129 citations

The amino acid sequence and gene organization of the heavy chain of the HLA-DR antigen: homology to immunoglobulins.

1982 • 121 citations

Structure and polymorphism of the HLA class II SB light chain genes.

1984 • 115 citations

Alpha and beta chains of SB and DR antigens are structurally distinct

1982 • 112 citations

Genetic mapping of a human class II antigen beta-chain cDNA clone to the SB region of the HLA complex.

1983 • 110 citations

4-NN-dimethylaminoazobenzene 4′-isothiocyanate, a new chromophoric reagent for protein sequence analysis

1976 • 102 citations

Two‐dimensional gel analysis of the polypeptides precipitated by a polymorphic HLA‐DR1,2,w6 monoclonal antibody: Evidence for a third locus

1982 • 102 citations

Die Primärstruktur der menschlichen freien Sekretkomponente und die Anordnung der Disulfidbrücken

1984 • 99 citations

Molecular organization of the HLA-SB region of the human major histocompatibility complex and evidence for two SB beta-chain genes.

1984 • 91 citations

Population studies of the HLA-linked SB antigens

1981 • 88 citations

Isolation of a cDNA clone coding for an SB β-chain

1984 • 87 citations

Tracts of high or low sequence divergence in the mouse major histocompatibility complex.

1984 • 86 citations

Evolution and Function of the Major Histocompatibility System: Facts and Speculations

1977 • 86 citations

Molecular map of the human HLA-SB (HLA-DP) region and sequence of an SB alpha (DP alpha) pseudogene.

1984 • 84 citations

SB subregion of the human major histocompatibility complex: gene organization, allelic polymorphism and expression in transformed cells.

1985 • 79 citations

Purification of HLA-linked B lymphocyte alloantigens in immunologically active form by preparative sodium dodecyl sulfate-gel electrophoresis and studies on their subunit association.

1977 • 79 citations

Organization of the transcriptional unit of a human class II histocompatibility antigen: HLA-DR heavy chain

1983 • 79 citations

Human la‐Type Alloantigens: Methods of Detection, Aspects of Chemistry and Biology, Markers for Disease States

1976 • 74 citations

The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region

1983 • 74 citations

Chemical properties of human Ia antigens

1977 • 70 citations

Allelic polymorphism and transassociation of molecules encoded by the HLA-DQ subregion.

1985 • 68 citations

Human Ia Antigens -- Purification and Molecular Structure

1977 • 64 citations

Separation of three class II antigens from a homozygous human B cell line.

1983 • 62 citations

Small subunit of I–A subregion antigens determines the allospecificity recognized by a monoclonal antibody

1980 • 60 citations

Structural and evolutionary analysis of HLA-D-region products

1984 • 59 citations

[47] β2-Microglobulin

1984 • 59 citations

Analysis of the HLA-linked SB gene system with cloned and uncloned alloreactive T-cell lines.

1982 • 55 citations

IUPAC-IUB Commission on Biochemical Nomenclature. A one-letter notation for amino acid sequences. Tentative rules

1969 • 49 citations

Molecular analysis of human class II transplantation antigens and their genes

1983 • 39 citations

Evolutionary Relationship Between HLA‐DR Antigen β‐Chains, HLA‐A, B, C Antigen Subunits and Immunoglobulin Chains

1981 • 38 citations

Isolation and characterization of detergent-solubilized human HLA-DR transplantation antigens

1979 • 37 citations

Primary Structure of Human Class II Histocompatibility Antigens 3rd Communication. Amino Acid Sequence Comparison between DR and DC Subclass Antigens Derived from a Lymphoblastoid B Cell Line Homozygous at the HLA Loci (HLA-A3,3; B7,7; Dw2,2; DR2,2; MT1,1; DC1,1;MB1,1)

1983 • 36 citations

Acquisition of the T cell repertoire

1978 • 30 citations

Biochemistry of MHC class II molecules

1985 • 29 citations

Structural relationship of the SB β-chain gene to HLA-D-region genes and murine I-region genes

1984 • 29 citations

Signal Sequences Distinguish Class II Histocompatibility Antigen ß Chains of Different Loci

1984 • 23 citations

KURZMITTEILUNG

1982 • 21 citations

Different functions and associations of HLA‐DR and HLA‐DQ(DC) antigens shown by serological, cellular and DNA assays

1985 • 20 citations

Primary structure of human class II histocompatibility antigens

1984 • 19 citations

Structural studies on the murine Ia alloantigens. VII. Further evidence for two-gene control of the E/C alloantigens.

1980 • 14 citations

Isolation and Characterization of the cDNA Clones and the Genomic Clones of the HLA Class II Antigen Heavy Chains

1984 • 14 citations

Genetic determination of antibody specificity

1978 • 14 citations

Biochemical analysis of the polymorphism of three HLA-D region antigens.

1983 • 14 citations

Primärstruktur der menschlichen Histokompatibilitätsantigene der Klasse II (HLA-D). I. Isolierung, Reinigung und Charakterisierung des α/β-Ketten-Komplexes des HLA-D einer homozygoten, lymphoblastoiden B-Zell-Linie, H2LCL (HLA-A3,3; B7,7; Dw2,2; DR2,2; MT1,1; DC1,1;MB1.1)

1984 • 11 citations

Two‐Chain Subunit Structure of HLA‐D Antigens

1977 • 11 citations

High performance liquid chromatography in protein and peptide chemistry

1983 • 10 citations

Heterogeneity of class II histocompatibility antigens isolated from a human lymphoblastoid B cell line homozygous at the HLA loci (HLA-A3, 3; B7, 7; Dw2, 2; DR2,2; DC1,1; MB1,1; MT1,1)

1983 • 9 citations

High Performance Liquid Chromatography in Protein and Peptide Chemistry

1982 • 4 citations

Distinct or Overlapping Functions of Human Class II Genes

1984 • 4 citations

The Human D Region as a Multigene Family

1984 • 3 citations