Apolipoprotein Eε4 modifies Alzheimer's disease onset in an E280A PS1 kindred

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Risk Factors for Alzheimer's Disease: A Prospective Analysis from the Canadian Study of Health and Aging

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Statistical Models and Methods for Lifetime Data

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Apolipoprotein E polymorphism and Alzheimer's disease

1993 • 1,076 citations

Early-Onset Autosomal Dominant Alzheimer Disease: Prevalence, Genetic Heterogeneity, and Mutation Spectrum

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Evidence for Genetic Linkage of Alzheimer's Disease to Chromosome 10q

2000 • 513 citations

The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology

1996 • 478 citations

Apolipoprotein E, ɛ4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region

1994 • 420 citations

Susceptibility Locus for Alzheimer's Disease on Chromosome 10

2000 • 386 citations

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model

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1996 • 302 citations

A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia

1998 • 287 citations

Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation

1997 • 254 citations

Apolipoprotein E: risk factor for Alzheimer disease.

1994 • 253 citations

Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene

1998 • 232 citations

Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene

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APOE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease

1994 • 131 citations

Contribution of APOE promoter polymorphisms to Alzheimer’s disease risk

2002 • 112 citations

Epistatic effect of APP717 mutation and apolipoprotein E genotype in familial Alzheimer's disease

1995 • 108 citations

Faster Haplotype Frequency Estimation Using Unrelated Subjects

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Wide range in age of onset for chromosome 1‐related familial Alzheimer's disease

1996 • 94 citations

E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles

1997 • 90 citations

Effect of APOE genotype and promoter polymorphism on risk of Alzheimer’s disease

2000 • 60 citations

The apolipoprotein E ε4 allele does not influence the clinical expression of the amyloid precursor protein gene codon 693 or 692 mutations

1994 • 59 citations

Effects of educational attainment on the clinical expression of Alzheimer's disease: Results from a research registry

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Unrecognized dementia: sociodemographic correlates

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Demencia tipo Alzheimer con agregación familiar en Antioquia, Colombia

1994 • 21 citations

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1987 • 17 citations