The apolipoprotein E ε4 allele does not influence the clinical expression of the amyloid precursor protein gene codon 693 or 692 mutations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

1993 • 4,145 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

1993 • 3,693 citations

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

1993 • 1,480 citations

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

1993 • 1,329 citations

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

1991 • 1,133 citations

Apolipoprotein E polymorphism and Alzheimer's disease

1993 • 1,076 citations

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the β–amyloid precursor protein gene

1992 • 725 citations

The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations.

1991 • 507 citations

Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases

1993 • 504 citations

Apolipoprotein E: Binding to Soluble Alzheimer′s β-Amyloid

1993 • 262 citations

Poisoning by radium carbonate.

1945 • 148 citations

Apolipoprotein E polymorphism in the Netherlands and its effect on plasma lipid and apolipoprotein levels

1988 • 129 citations

Familial dysbetalipoproteinemia associated with apolipoprotein E3-Leiden in an extended multigeneration pedigree.

1991 • 94 citations

DNA diagnosis for hereditary cerebral hemorrhage with amyloidosis (Dutch type)

1991 • 77 citations

Hereditary Cerebral Hemorrhage With Amyloidosis-Dutch Type

1990 • 71 citations

Hereditary cerebral hemorrhage with amyloidosis — Dutch type

1989 • 35 citations