Reduced Size of Retinal Ganglion Cell Axons and Hypomyelination in Mice Lacking Brain-Derived Neurotrophic Factor

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Physiology of the Neurotrophins

1996 • 1,908 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.

1995 • 1,416 citations

Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice

1996 • 1,219 citations

Distribution of Brain-Derived Neurotrophic Factor (BDNF) Protein and mRNA in the Normal Adult Rat CNS: Evidence for Anterograde Axonal Transport

1997 • 1,093 citations

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development

1994 • 1,046 citations

Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture

1995 • 847 citations

Effects of ocular injury and administration ofbrain-derived neurotrophic factor on survival and regrowth of axotomized retinalganglion cells.

1994 • 727 citations

Induction of myelination in the central nervous system by electrical activity.

1996 • 646 citations

Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons

1993 • 622 citations

A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development

1994 • 585 citations

Effects of brain-derived neurotrophic factor on optic axon branching and remodelling in vivo

1995 • 583 citations

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo

1993 • 543 citations

Cell death during differentiation of the retina in the mouse

1984 • 531 citations

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells

1986 • 519 citations

The role of neurotrophins in the developing nervous system

1994 • 472 citations

Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat

1983 • 437 citations

Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4

1995 • 413 citations

Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study.

1996 • 400 citations

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

1995 • 381 citations

A crucial role for neurotrophin-3 in oligodendrocyte development

1994 • 353 citations

Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice.

1996 • 350 citations

Anterograde transport of neurotrophins and axodendritic transfer in the developing visual system

1996 • 284 citations

Synaptic Innervation Density Is Regulated by Neuron-Derived BDNF

1997 • 280 citations

Neurotrophic Survival Molecules for Motoneurons: An Embarrassment of Riches

1996 • 271 citations

Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain

1994 • 237 citations

TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons.

1996 • 231 citations

Target size regulates calibre and myelination of sympathetic axons

1989 • 216 citations

Systems-matching by degeneration

1978 • 210 citations

Survival and Axonal Elongation of Adult Rat Retinal Ganglion Cells

1989 • 210 citations

Growth cones, dying axons, and developmental fluctuations in the fiber population of the cat's optic nerve

1986 • 207 citations

TrkB Signaling Is Required for Postnatal Survival of CNS Neurons and Protects Hippocampal and Motor Neurons from Axotomy-Induced Cell Death

1997 • 201 citations

Ganglion cell death during normal retinal development in the chick: Comparisons with cell death induced by early target field destruction

1979 • 189 citations

Nerve Growth Factor and Neurotrophin-3 Differentially Regulate the Proliferation and Survival of Developing Rat Brain Oligodendrocytes

1996 • 175 citations

Neurotrophins in the developing and regenerating visual system.

1998 • 173 citations

Expression of brain-derived neurotrophic factor and of its functional receptor in neonatal and adult rat retina

1995 • 162 citations

The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age

1989 • 154 citations

Different forms of the neurotrophin receptor TrkB mRNA predominate in rat retina and optic nerve

1993 • 151 citations

Localization of Cellular Storage Compartments and Sites of Constitutive and Activity-Dependent Release of Nerve Growth Factor (NGF) in Primary Cultures of Hippocampal Neurons

1996 • 151 citations

Glial cells are increased proportionally in transgenic optic nerves with increased numbers of axons

1996 • 149 citations

BDNF in the development of the visual system of Xenopus

1994 • 148 citations

At least two mechanisms are involved in the death of retinal ganglion cells following target ablation in neonatal rats

1995 • 138 citations

Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos

1994 • 133 citations

Control of early cell death by BDNF in the chick retina

1997 • 127 citations

Expression of neurotrophins and Trk receptors in the avian retina

1996 • 111 citations

Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: Effects of kainate lesions in the superior colliculus

1986 • 93 citations

Expression of the BDNF gene in the developing visual system of the chick

1994 • 92 citations

Thyroid Hormones and the Central Nervous System

1994 • 86 citations

Neurotrophin-3 Antibodies Disrupt the Normal Development of the Chick Retina

1996 • 68 citations

Neurotrophins and their receptors in the rat pituitary gland: regulation of BDNF and trk B mRNA levels by adrenal hormones

1994 • 58 citations

Life and death in the nervous system

1993 • 18 citations

Neurological consequences of protein and protein-calorie undernutrition.

1991 • 14 citations

Brain-Derived Neurotrophic Factor and the Developing Chick Retina

1995 • 8 citations

Life and death in the nervous system

1994 • 6 citations