Expression of neurotrophins and Trk receptors in the avian retina

Purification of a new neurotrophic factor from mammalian brain.

1982 • 1,762 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1994 • 1,066 citations

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

1994 • 1,065 citations

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development

1994 • 1,046 citations

Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo

1951 • 947 citations

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

1990 • 899 citations

Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB

1991 • 847 citations

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in xenopus ovary

1991 • 836 citations

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1991 • 819 citations

Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

1990 • 700 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor

1987 • 555 citations

Primary structure and biological activity of a novel human neurotrophic factor

1990 • 553 citations

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo

1993 • 543 citations

Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons

1992 • 521 citations

Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma.

1992 • 521 citations

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells

1986 • 519 citations

Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex.

1992 • 515 citations

Cells Expressing mRNA for Neurotrophins and their Receptors During Embryonic Rat Development

1992 • 499 citations

Alternative forms of rat TrkC with different functional capabilities

1993 • 374 citations

Evidence for dendritic competition in the developing retina

1982 • 345 citations

Increased production of the TrkB protein tyrosine kinase receptor after brain insults

1993 • 344 citations

Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons

1993 • 338 citations

The trk B tyrosine protein kinase is a receptor for neurotrophin-4

1992 • 326 citations

The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells

1993 • 290 citations

Cloning and expression of a cDNA encoding a novel human neurotrophic factor

1990 • 199 citations

Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival

1992 • 195 citations

Neurotrophin 3 is a mitogen for cultured neural crest cells.

1992 • 192 citations

Ganglion cell death during normal retinal development in the chick: Comparisons with cell death induced by early target field destruction

1979 • 189 citations

trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities.

1993 • 178 citations

Role of the neurotrophic factors BDNF and NGF in the commitment of pluripotent neural crest cells

1991 • 176 citations

The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age

1989 • 154 citations

Different forms of the neurotrophin receptor TrkB mRNA predominate in rat retina and optic nerve

1993 • 151 citations

BDNF in the development of the visual system of Xenopus

1994 • 148 citations

Binding characteristics of brain-derived neurotrophic factor to its receptors on neurons from the chick embryo

1988 • 142 citations

On the synaptogenic sequence in the chick retina

1974 • 141 citations

Developmentally Regulated Expression of HDNF/NT‐3 mRNA in Rat Spinal Cord Motoneurons and Expression of BDNF mRNA in Embryonic Dorsal Root Ganglion

1991 • 138 citations

The time of origin and the pattern of survival of neurons in the isthmo‐optic nucleus of the chick

1976 • 133 citations

Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos

1994 • 133 citations

The duration of neurotrophic factor independence in early sensory neurons is matched to the time course of target field innervation

1991 • 123 citations

Structure and expression of the chicken beta nerve growth factor gene.

1986 • 121 citations

Synaptic Connections of the Centrifugal Fibers in the Pigeon Retina

1965 • 119 citations

A specific projection of retinal displaced ganglion cells to the nucleus of the basal optic root in the chicken

1979 • 119 citations

Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion

1993 • 106 citations

Complete nucleotide sequence of the messenger RNA coding for chicken muscle glyceraldehyde-3-phosphate dehydrogenase

1984 • 102 citations

An autoradiographic analysis of neurogenesis in the chick retinain vitro andin vivo

1989 • 96 citations

Expression and binding characteristics of the BDNF receptor chick trkB

1993 • 94 citations

The Retina a Model for Cell Biology Studies

1986 • 93 citations

Expression of the BDNF gene in the developing visual system of the chick

1994 • 92 citations

The survival of neonatal rat retinal ganglion cells in vitro is enhanced in the presence of appropriate parts of the brain

1982 • 89 citations

Cellular Localization of Brain‐derived Neurotrophic Factor and Neurotrophin‐3 mRNA Expression in the Early Chicken Embryo

1993 • 83 citations

Role of neurotrophins in the control of neural development: Neurotrophin-3 promotes both neuron differentiation and survival of cultured chick retinal cells

1994 • 72 citations

Trophic Factors Produced by Retinal Cells Increase the Survival of Retinal Ganglion Cells In Vitro

1993 • 70 citations

Cellular Neurobiology

1991 • 70 citations

Generation and degeneration of retinal ganglion cells in the chicken

1976 • 62 citations

Survival of isthmo-optic neurons after early removal of one eye

1984 • 59 citations

The distribution of centrifugal terminals in the pigeon retina

1983 • 57 citations

NT-4/5 reduces naturally occurring retinal ganglion cell death in neonatal rats

1994 • 55 citations

Recombinant human β‐nerve growth factor (NGF): Biological activity and properties in an enzyme immunoassay

1990 • 54 citations

Detection of nerve growth factor mRNA in the developing chicken embryo

1988 • 53 citations

Molecular cloning and cellular localization of trk C in the chicken embryo

1993 • 52 citations

Oncogene expression in retinal horizontal cells of transgenic mice results in a cascade of neurodegeneration

1993 • 45 citations

Organotypic cultures of neural retina: Neurite outgrowth stimulated by brain extracts

1983 • 44 citations

Abrupt loss of dependence of retinopetal neurons on their target cells, as shown by intraocular injections of kainate in chick embryos

1987 • 43 citations

Comparison of mammalian, chicken andXenopusbrain-derived neurotrophic factor coding sequences

1991 • 39 citations

Developmental expression of trkB and low-affinity NGF receptor in the rat retina

1993 • 39 citations

Developing Rat Retinal Ganglion Cells Express the Functional NGF Receptor p140trkA

1993 • 37 citations

Neurotrophin-3 acquires NGF-like activity after exchange to five NGF amino acid residues: Molecular analysis of the sites in NGF mediating the specific interaction with the NGF high affinity receptor

1994 • 31 citations

Production and Characterization of Biologically Active Recombinant Beta Nerve Growth Factor

1988 • 31 citations

Neurotrophin‐3 receptors in the developing chicken retina

1993 • 28 citations

Gene regulation of trkB and trkC in the chick retina by light/darkness exposure.

1994 • 26 citations

Production and characterization of biologically active recombinant beta nerve growth factor.

1988 • 24 citations

Target-field specificity in the induction of retinal neurite outgrowth

1987 • 21 citations

Dendritic competition in the developing retina: Ganglion cell density gradients and laterally displaced dendrites

1993 • 21 citations

Biological and Immunological Properties of Recombinant Human, Rat, and Chicken Nerve Growth Factors: A Comparative Study

1991 • 20 citations

Molecular cloning and expression of a novel truncated form of chicken trkC

1993 • 18 citations

Changing the light intensity of the visual environment results in large differences in numbers of synapses and in photoreceptor size in the retina of the young adult rat

1993 • 17 citations

THE DEVELOPMENT OF RETINAL NETWORKS

1986 • 14 citations