An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells☆

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

2001 • 5,526 citations

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

2001 • 4,997 citations

Ulcerative Colitis

2001 • 3,087 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

2002 • 2,555 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

B cells regulate autoimmunity by provision of IL-10

2002 • 1,562 citations

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice

1988 • 1,562 citations

Enhanced Th1 Activity and Development of Chronic Enterocolitis in Mice Devoid of Stat3 in Macrophages and Neutrophils

1999 • 1,228 citations

Chronic Intestinal Inflammatory Condition Generates IL-10-Producing Regulatory B Cell Subset Characterized by CD1d Upregulation

2002 • 929 citations

Prevention of Arthritis by Interleukin 10–producing B Cells

2003 • 816 citations

Transcriptional Mechanisms Underlying Lymphocyte Tolerance

2002 • 658 citations

The role of Th1/Th2 polarization in mucosal immunity

2002 • 613 citations

Hyperproliferation and Dysregulation ofIL-4 Expression in NF-ATp-Deficient Mice

1996 • 456 citations

Tolerance and Autoimmunity

2001 • 453 citations

NFATc1 and NFATc2 Together Control Both T and B Cell Activation and Differentiation

2001 • 397 citations

Inhibitory Function of Two NFAT Family Members in Lymphoid Homeostasis and Th2 Development

1998 • 325 citations

Calcineurin: From structure to function

2001 • 298 citations

The Key Role of Macrophages in the Immunopathogenesis of Inflammatory Bowel Disease

2000 • 289 citations

The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS)

2002 • 205 citations

Immunophilins: Switched on protein binding domains?

2000 • 130 citations

Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice.

2003 • 108 citations

Regulation of Allergic Inflammation and Eosinophil Recruitment in Mice Lacking the Transcription Factor NFAT1: Role of Interleukin-4 (IL-4) and IL-5

1998 • 80 citations

Functional differentiation of T cells in the intestine of T cell receptor transgenic mice

1997 • 51 citations

Cyclosporin A treatment in inflammatory bowel disease

1989 • 46 citations

NF-ATc Isoforms Are Differentially Expressed and Regulated in Murine T and Mast Cells

1999 • 29 citations

Role of the innate immune system in the development of chronic colitis

2002 • 17 citations

Immunosuppressive drugs in the treatment of inflammatory bowel disease.

1998 • 10 citations