STAT3 activation accompanies keratinocyte differentiation.

STATs and Gene Regulation

1997 • 3,927 citations

Essential role of Stat6 in IL-4 signalling

1996 • 1,563 citations

E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins

1992 • 1,552 citations

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

1997 • 1,306 citations

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

1995 • 1,154 citations

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 • 1,106 citations

Enhanced DNA-Binding Activity of a Stat3-Related Protein in Cells Transformed by the Src Oncoprotein

1995 • 945 citations

Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: Activation of the cross-linking by calcium ions

1979 • 792 citations

Epidermal differentiation: the bare essentials.

1990 • 651 citations

A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells.

1996 • 589 citations

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.

1989 • 569 citations

Terminal differentiation of cultured human epidermal cells

1977 • 521 citations

Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.

1994 • 514 citations

Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

1994 • 493 citations

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.

1994 • 493 citations

Epithelial stem cells in vivo

1988 • 446 citations

Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression.

1984 • 440 citations

MyoD-Induced Expression of p21 Inhibits Cyclin-Dependent Kinase Activity upon Myocyte Terminal Differentiation

1995 • 416 citations

Fibronectin inhibits the terminal differentiation of human keratinocytes

1989 • 402 citations

Activation and Association of Stat3 with Src in v-Src-Transformed Cell Lines

1996 • 372 citations

Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells.

1997 • 370 citations

The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies.

1983 • 355 citations

Jak-STAT Signaling Induced by the v- abl oncogene

1995 • 341 citations

Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

1995 • 338 citations

Regulation of STAT‐dependent pathways by growth factors and cytokines

1996 • 297 citations

Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27^Kip1

1997 • 260 citations

Introduction to the E2F Family: Protein Structure and Gene Regulation

1996 • 249 citations

Platelet-Derived Growth Factor Induces Phosphorylation of Multiple JAK Family Kinases and STAT Proteins

1996 • 247 citations

Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation.

1996 • 223 citations

Roles of JAKs in Activation of STATs and Stimulation of c-fos Gene Expression by Epidermal Growth Factor

1996 • 221 citations

In vitro activation of Stat3 by epidermal growth factor receptor kinase

1996 • 195 citations

Repression of p27^kip1 Synthesis by Platelet-Derived Growth Factor in BALB/c 3T3 Cells

1996 • 168 citations

STAT Activation by Epidermal Growth Factor (EGF) and Amphiregulin

1996 • 165 citations

The use of retinoic acid to probe the relation between hyperproliferation-associated keratins and cell proliferation in normal and malignant epidermal cells.

1989 • 155 citations

Abrogation of Interleukin-3 Dependence of Myeloid Cells by the v-src Oncogene Requires SH2 and SH3 Domains Which Specify Activation of STATs

1997 • 108 citations

Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation.

1997 • 103 citations

Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells.

1994 • 102 citations

Two Functionally Distinct Classes of Growth Arrest States in Human Prokeratinocytes That Regulate Clonogenic Potential

1986 • 87 citations

Oct-6: a Regulator of Keratinocyte Gene Expression in Stratified Squamous Epithelia

1994 • 84 citations

Commitment to differentiation and expression of early differentiation markers in murine keratinocytes in vitro are regulated independently of extracellular calcium concentrations.

1993 • 53 citations

Expression and growth inhibitory effect of decapentaplegic Vg-related protein 6: evidence for a regulatory role in keratinocyte differentiation.

1994 • 49 citations

Characterization of the Mouse Loricrin Gene: Linkage with Profilaggrin and the Flaky Tail and Soft Coat Mutant Loci on Chromosome 3

1994 • 40 citations

Growth and differentiation stimuli induce different and distinct increases in intracellular free calcium in human keratinocytes

1993 • 35 citations