Ligand–protein interactions in nuclear receptors of hormones

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

A decade of molecular biology of retinoic acid receptors

1996 • 2,893 citations

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

The coregulator exchange in transcriptional functions of nuclear receptors

2000 • 2,219 citations

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

1998 • 1,902 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

1999 • 1,157 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

1999 • 963 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Structure and specificity of nuclear receptor–coactivator interactions

1998 • 922 citations

Coactivator and corepressor complexes in nuclear receptor function

1999 • 909 citations

Recent Advances in Chemoprevention of Cancer

1997 • 837 citations

The nuclear receptor ligand-binding domain: structure and function

1998 • 829 citations

The Crystal Structure of the Nuclear Receptor for Vitamin D Bound to Its Natural Ligand

2000 • 802 citations

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

1993 • 738 citations

Crystallographic comparison of the estrogen and progesterone receptor’s ligand binding domains

1998 • 690 citations

Atomic structure of progesterone complexed with its receptor

1998 • 654 citations

The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors

1999 • 637 citations

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

1998 • 609 citations

Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors

2000 • 563 citations

Molecular determinants of nuclear receptor-corepressor interaction

1999 • 516 citations

Increasing the Complexity of Coactivation in Nuclear Receptor Signaling

1999 • 449 citations

Retinoids in cancer chemoprevention

1996 • 432 citations

Mechanism of corepressor binding and release from nuclear hormone receptors

1999 • 414 citations

Crystal Structure of a Heterodimeric Complex of RAR and RXR Ligand-Binding Domains

2000 • 394 citations

Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators

1998 • 337 citations

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

2000 • 332 citations

Transcription factors 3: nuclear receptors.

1995 • 327 citations

Nuclear-Receptor Ligands and Ligand-Binding Domains

1999 • 314 citations

Crystal Structure of the Ligand Binding Domain of the Human Nuclear Receptor PPARγ

1998 • 256 citations

Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism.

1993 • 185 citations

Nuclear Receptors in Sicily: All in the Famiglia

1997 • 152 citations

Nuclear hormone receptors: ligand-activated regulators of transcription and diverse cell responses

1996 • 143 citations

Conformational adaptation of agonists to the human nuclear receptor RARγ

1998 • 140 citations

Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists

1999 • 90 citations

Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARγ

2000 • 81 citations

Retinoic acid receptor: a simulation analysis of retinoic acid binding and the resulting conformational changes

1999 • 79 citations

The biologic basis for the use of retinoids in cancer prevention and treatment

1999 • 37 citations

Mechanisms of transcriptional activation by retinoic acid receptors

1997 • 34 citations

Transcriptional control: How nuclear receptors get turned on

1996 • 19 citations