Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

Refinement of Macromolecular Structures by the Maximum-Likelihood Method

1997 • 14,729 citations

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β

1997 • 4,422 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

1998 • 1,902 citations

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1997 • 1,724 citations

Generation and reproductive phenotypes of mice lacking estrogen receptor β

1998 • 1,680 citations

Phyto-oestrogens and Western Diseases

1997 • 1,280 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

ALSCRIPT: a tool to format multiple sequence alignments

1993 • 1,125 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

Detection, delineation, measurement and display of cavities in macromolecular structures

1994 • 964 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Structure and specificity of nuclear receptor–coactivator interactions

1998 • 922 citations

The nuclear receptor ligand-binding domain: structure and function

1998 • 829 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

Differential Response of Estrogen Receptor α and Estrogen Receptor β to Partial Estrogen Agonists/Antagonists

1998 • 776 citations

Crystallographic comparison of the estrogen and progesterone receptor’s ligand binding domains

1998 • 690 citations

Basic guide to the mechanisms of antiestrogen action.

1998 • 688 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site

1997 • 611 citations

Co-activators and co-repressors in the integration of transcriptional responses

1998 • 606 citations

Insights from the study of animals lacking functional estrogen receptor

1994 • 587 citations

Hormone-Dependent Coactivator Binding to a Hydrophobic Cleft on Nuclear Receptors

1998 • 580 citations

Monoclonal antibodies to human estrogen receptor.

1980 • 545 citations

The Complete Primary Structure of Human Estrogen Receptor β (hERβ) and Its Heterodimerization with ER αin Vivoandin Vitro

1998 • 510 citations

Interaction of Steroid Hormone Receptors with the Transcription Initiation Complex

1996 • 399 citations

Hydrogen bonding in globular proteins

1992 • 396 citations

A controlled trial of raloxifene (LY139481) HCl: Impact on bone turnover and serum lipid profile in healthy postmenopausal women

1996 • 362 citations

Transcription Activation by the Human Estrogen Receptor Subtypeβ (ERβ) Studied with ERβ and ERα Receptor Chimeras¹

1998 • 267 citations

Molecular determinants of tissue selectivity in estrogen receptor modulators

1997 • 240 citations

Conformational adaptation of agonists to the human nuclear receptor RARγ

1998 • 140 citations

Antiestrogenic Action of Raloxifene and Tamoxifen: Today and Tomorrow

1998 • 80 citations

Raloxifene: Magic bullet for heart and bone?

1998 • 26 citations