The Crystal Structure of the Nuclear Receptor for Vitamin D Bound to Its Natural Ligand

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

1998 • 1,902 citations

Nuclear Receptor Coregulators: Cellular and Molecular Biology*

1999 • 1,783 citations

Structure-Function Relationships in the Vitamin D Endocrine System*

1995 • 1,182 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Atomic structure of progesterone complexed with its receptor

1998 • 654 citations

Increasing the Complexity of Coactivation in Nuclear Receptor Signaling

1999 • 449 citations

Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1

1991 • 421 citations

A novel protein complex that interacts with the vitamin D₃ receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system

1998 • 391 citations

Structure-function relationships in the vitamin D endocrine system

1995 • 268 citations

A Nuclear Hormone Receptor Corepressor Mediates Transcriptional Silencing by Receptors with Distinct Repression Domains

1996 • 233 citations

Selective Interaction of Vitamin D Receptor with Transcriptional Coactivators by a Vitamin D Analog

1999 • 201 citations

Distinct Conformational Changes Induced by 20-epi Analogues of 1α,25-Dihydroxyvitamin D3 Are Associated with Enhanced Activation of the Vitamin D Receptor

1995 • 201 citations

Mechanisms and Functions of Vitamin D

2009 • 193 citations

Vitamin D receptor interaction with specific DNA. Association as a 1,25-dihydroxyvitamin D3-modulated heterodimer.

1991 • 156 citations

Two mutations in the hormone binding domain of the vitamin D receptor cause tissue resistance to 1,25 dihydroxyvitamin D3.

1993 • 152 citations

Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3

1999 • 149 citations

Conformational adaptation of agonists to the human nuclear receptor RARγ

1998 • 140 citations

Generalized method of determining heavy-atom positions using the difference Patterson function

1987 • 139 citations

Comparison of 6-s-cis- and 6-s-trans-Locked Analogs of 1α,25-Dihydroxyvitamin D3 Indicates That the 6-s-cis Conformation Is Preferred for Rapid Nongenomic Biological Responses and That Neither 6-s-cis- nor 6-s-trans-Locked Analogs Are Preferred for Genomic Biological Responses

1997 • 121 citations

Vitamin D receptors from patients with resistance to 1,25-dihydroxyvitamin D3: point mutations confer reduced transactivation in response to ligand and impaired interaction with the retinoid X receptor heterodimeric partner.

1996 • 120 citations

Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation.

1996 • 108 citations

The Biological Activity of Nonsteroidal Vitamin D Hormone Analogs Lacking Both the C- and D-Rings

1998 • 70 citations

Statistical test of models and computerised parameter estimation for aldosterone binding in rat kidney

1978 • 52 citations

Three-dimensional model of the ligand binding domain of the nuclear receptor for 1?,25-dihydroxy-vitamin D3

1999 • 48 citations

Synthesis and biological activity of 2-methyl-20-epi analogues of 1α,25-dihydroxyvitamin D3

1998 • 32 citations

Crystal and molecular structure of 1,25-dihydroxycholecalciferol

1996 • 26 citations

Nuclear Receptor Co-regulators

2013 • 21 citations

Characterization of the activation function-2 domain of the human 1,25-dihydroxyvitamin D3 receptor

1998 • 16 citations