Regulated nucleosome mobility and the histone code

Crystal structure of the nucleosome core particle at 2.8 Å resolution

1997 • 8,906 citations

The language of covalent histone modifications

2000 • 8,260 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

Cooperation between Complexes that Regulate Chromatin Structure and Transcription

2002 • 1,474 citations

Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9Å Resolution

2002 • 1,427 citations

ATP-Driven Exchange of Histone H2AZ Variant Catalyzed by SWR1 Chromatin Remodeling Complex

2003 • 1,264 citations

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

2002 • 1,050 citations

Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination

2004 • 955 citations

Dot1p Modulates Silencing in Yeast by Methylation of the Nucleosome Core

2002 • 818 citations

Histone Deimination Antagonizes Arginine Methylation

2004 • 796 citations

ATP-Dependent Nucleosome Remodeling

2002 • 779 citations

Histone H2A variants H2AX and H2AZ

2002 • 749 citations

Transitions in Distinct Histone H3 Methylation Patterns at the Heterochromatin Domain Boundaries

2001 • 746 citations

Bromodomain: an acetyl‐lysine binding domain

2002 • 722 citations

Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions

1995 • 702 citations

The Nucleosome

2004 • 636 citations

Binary switches and modification cassettes in histone biology and beyond

2003 • 628 citations

Ikaros DNA-Binding Proteins Direct Formation of Chromatin Remodeling Complexes in Lymphocytes

1999 • 583 citations

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

2002 • 555 citations

Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters

1997 • 546 citations

Conformational Dynamics of the Chromatin Fiber in Solution: Determinants, Mechanisms, and Functions

2002 • 533 citations

Function and Selectivity of Bromodomains in Anchoring Chromatin-Modifying Complexes to Promoter Nucleosomes

2002 • 526 citations

Chromatin Fiber Folding: Requirement for the Histone H4 N-terminal Tail

2003 • 509 citations

Trans-histone regulatory pathway in chromatin

2002 • 502 citations

Histone H3.3 is enriched in covalent modifications associated with active chromatin

2004 • 498 citations

Ubiquitination of Histone H2B by Rad6 Is Required for Efficient Dot1-mediated Methylation of Histone H3 Lysine 79

2002 • 424 citations

Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions

2001 • 398 citations

NuRD and SIN3

2000 • 384 citations

Nucleosomes facilitate their own invasion

2004 • 376 citations

Nucleosome mobilization catalysed by the yeast SWI/SNF complex

1999 • 354 citations

Regulation of Chromatin Remodeling by Inositol Polyphosphates

2003 • 349 citations

Modulation of ATP-Dependent Chromatin-Remodeling Complexes by Inositol Polyphosphates

2003 • 336 citations

Structure and dynamic behavior of nucleosomes

2003 • 300 citations

Coordinate Regulation of Yeast Ribosomal Protein Genes Is Associated with Targeted Recruitment of Esa1 Histone Acetylase

2000 • 286 citations

Human SWI/SNF Interconverts a Nucleosome between Its Base State and a Stable Remodeled State

1998 • 283 citations

Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes

2001 • 278 citations

Essential Functional Interactions of SAGA, a Saccharomyces cerevisiae Complex of Spt, Ada, and Gcn5 Proteins, With the Snf/Swi and Srb/Mediator Complexes

1997 • 277 citations

Identification of novel histone post-translational modifications by peptide mass fingerprinting

2003 • 273 citations

Multiple Links between the NuA4 Histone Acetyltransferase Complex and Epigenetic Control of Transcription

2000 • 263 citations

Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription.

1995 • 245 citations

Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14

2004 • 233 citations

The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription

2002 • 228 citations

Persistent Site-Specific Remodeling of a Nucleosome Array by Transient Action of the SWI/SNF Complex

1996 • 227 citations

Critical Role for the Histone H4 N Terminus in Nucleosome Remodeling by ISWI

2001 • 224 citations

BRG-1 Is Recruited to Estrogen-Responsive Promoters and Cooperates with Factors Involved in Histone Acetylation

2000 • 221 citations

Mobility of positioned nucleosomes on 5 S rDNA

1991 • 211 citations

Widespread Collaboration of Isw2 and Sin3-Rpd3 Chromatin Remodeling Complexes in Transcriptional Repression

2001 • 210 citations

Role for ADA/GCN5 Products in Antagonizing Chromatin-Mediated Transcriptional Repression

1997 • 203 citations

Activated RSC–Nucleosome Complex and Persistently Altered Form of the Nucleosome

1998 • 198 citations

The Gcn5 bromodomain co-ordinates nucleosome remodelling

2000 • 194 citations

Perturbation of nucleosome core structure by the SWI/SNF complex persists after its detachment, enhancing subsequent transcription factor binding

1998 • 180 citations

The many colours of chromodomains

2004 • 171 citations

Phosphorylation of linker histones regulates ATP-dependent chromatin remodeling enzymes

2002 • 170 citations

Histone tails modulate nucleosome mobility and regulate ATP-dependent nucleosome sliding by NURF

2001 • 168 citations

A Negative Regulator of HO Transcription, SIN1 (SPT2), Is a Nonspecific DNA-Binding Protein Related to HMG1

1991 • 157 citations

A critical epitope for substrate recognition by the nucleosome remodeling ATPase ISWI

2002 • 155 citations

The SWI/SNF Complex Creates Loop Domains in DNA and Polynucleosome Arrays and Can Disrupt DNA-Histone Contacts within These Domains

1999 • 152 citations

Nucleosome remodeling: one mechanism, many phenomena?

2003 • 145 citations

Identification of Acetylation and Methylation Sites of Histone H3 from Chicken Erythrocytes by High-Accuracy Matrix-Assisted Laser Desorption Ionization–Time-of-Flight, Matrix-Assisted Laser Desorption Ionization–Postsource Decay, and Nanoelectrospray Ionization Tandem Mass Spectrometry

2002 • 144 citations

ISWI Induces Nucleosome Sliding on Nicked DNA

2001 • 136 citations

Application of mass spectrometry to the identification and quantification of histone post‐translational modifications

2004 • 135 citations

Crystal structures of histone Sin mutant nucleosomes reveal altered protein–DNA interactions

2004 • 130 citations

A core nucleosome surface crucial for transcriptional silencing

2002 • 130 citations

Sin mutations alter inherent nucleosome mobility

2004 • 123 citations

NEW EMBO MEMBER'S REVIEW: Nucleosome sliding: facts and fiction

2002 • 122 citations

Nucleosome Disruption by Human SWI/SNF Is Maintained in the Absence of Continued ATP Hydrolysis

1996 • 94 citations

Antagonistic remodelling by Swi–Snf and Tup1–Ssn6 of an extensive chromatin region forms the background for FLO1 gene regulation

2001 • 93 citations

A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1.

1991 • 77 citations

TAF1 Activates Transcription by Phosphorylation of Serine 33 in Histone H2B

2004 • 68 citations

Stable Remodeling of Tailless Nucleosomes by the Human SWI-SNF Complex

1999 • 66 citations

The SIN domain of the histone octamer is essential for intramolecular folding of nucleosomal arrays

2002 • 59 citations

ATP-dependent Nucleosome Remodeling and Histone Hyperacetylation Synergistically Facilitate Transcription of Chromatin

2001 • 55 citations

Identification of Methylation and Acetylation Sites on Mouse Histone H3 Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight and Nanoelectrospray Ionization Tandem Mass Spectrometry

2003 • 46 citations

Mutations in Chromatin Components Suppress a Defect of Gcn5 Protein in Saccharomyces cerevisiae

1998 • 38 citations

Transcriptional control: SWItched-on mobility

1999 • 25 citations