Cooperation between Complexes that Regulate Chromatin Structure and Transcription

Crystal structure of the nucleosome core particle at 2.8 Å resolution

1997 • 8,906 citations

The language of covalent histone modifications

2000 • 8,260 citations

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1964 • 2,410 citations

Histone Acetyltransferases

2001 • 1,745 citations

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 • 1,660 citations

Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription

2000 • 1,658 citations

Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

1996 • 1,567 citations

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

2001 • 1,480 citations

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

1993 • 1,116 citations

Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

1994 • 853 citations

The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities

1998 • 791 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

Ordered Recruitment of Chromatin Modifying and General Transcription Factors to the IFN-β Promoter

2000 • 716 citations

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

1999 • 705 citations

Ordered Recruitment of Transcription and Chromatin Remodeling Factors to a Cell Cycle– and Developmentally Regulated Promoter

1999 • 703 citations

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

1998 • 655 citations

Purification and properties of an ATP-dependent nucleosome remodeling factor

1995 • 600 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

Ikaros DNA-Binding Proteins Direct Formation of Chromatin Remodeling Complexes in Lymphocytes

1999 • 583 citations

Disruption of Higher-Order Folding by Core Histone Acetylation Dramatically Enhances Transcription of Nucleosomal Arrays by RNA Polymerase III

1998 • 568 citations

Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2α subunit of NuRD

2001 • 504 citations

Global histone acetylation and deacetylation in yeast

2000 • 457 citations

Highly Specific Antibodies Determine Histone Acetylation Site Usage in Yeast Heterochromatin and Euchromatin

2001 • 436 citations

Promoter targeting and chromatin remodeling by the SWI/SNF complex

2000 • 433 citations

A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase

1998 • 426 citations

Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae

2000 • 398 citations

NuRD and SIN3

2000 • 384 citations

The ISWI Chromatin-Remodeling Protein Is Required for Gene Expression and the Maintenance of Higher Order Chromatin Structure In Vivo

2000 • 383 citations

Expanded Lysine Acetylation Specificity of Gcn5 in Native Complexes

1999 • 371 citations

Recruitment of HAT Complexes by Direct Activator Interactions with the ATM-Related Tra1 Subunit

2001 • 369 citations

Histone Acetyltransferase Complexes Stabilize SWI/SNF Binding to Promoter Nucleosomes

2001 • 359 citations

Nucleosome Movement by CHRAC and ISWI without Disruption or trans-Displacement of the Histone Octamer

1999 • 357 citations

Nucleosome mobilization catalysed by the yeast SWI/SNF complex

1999 • 354 citations

Functional significance of histone deacetylase diversity

2001 • 351 citations

dMi-2, a Hunchback-Interacting Protein That Functions in Polycomb Repression

1998 • 349 citations

The many HATs of transcription coactivators

2000 • 342 citations

ATP-Dependent Histone Octamer Sliding Mediated by the Chromatin Remodeling Complex NURF

1999 • 334 citations

ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly

1999 • 331 citations

Mobile nucleosomes--a general behavior.

1992 • 309 citations

The Isw2 Chromatin Remodeling Complex Represses Early Meiotic Genes upon Recruitment by Ume6p

2000 • 307 citations

Histone Octamer Transfer by a Chromatin-Remodeling Complex

1999 • 290 citations

Coordinate Regulation of Yeast Ribosomal Protein Genes Is Associated with Targeted Recruitment of Esa1 Histone Acetylase

2000 • 286 citations

Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes

2001 • 278 citations

Essential Functional Interactions of SAGA, a Saccharomyces cerevisiae Complex of Spt, Ada, and Gcn5 Proteins, With the Snf/Swi and Srb/Mediator Complexes

1997 • 277 citations

Cell cycle-regulated histone acetylation required for expression of the yeast HO gene

1999 • 275 citations

Common Themes in Mechanisms of Gene Silencing

2001 • 275 citations

Generation of Superhelical Torsion by ATP-Dependent Chromatin Remodeling Activities

2000 • 269 citations

Selectivity of chromatin-remodelling cofactors for ligand-activated transcription

2001 • 251 citations

Dual Functions of Largest NURF Subunit NURF301 in Nucleosome Sliding and Transcription Factor Interactions

2001 • 251 citations

Activation Domain–Mediated Targeting of the SWI/SNF Complex to Promoters Stimulates Transcription from Nucleosome Arrays

1999 • 245 citations

A histone octamer can step around a transcribing polymerase without leaving the template

1994 • 238 citations

Global Role for Chromatin Remodeling Enzymes in Mitotic Gene Expression

2000 • 232 citations

Critical Role for the Histone H4 N Terminus in Nucleosome Remodeling by ISWI

2001 • 224 citations

BRG-1 Is Recruited to Estrogen-Responsive Promoters and Cooperates with Factors Involved in Histone Acetylation

2000 • 221 citations

Widespread Collaboration of Isw2 and Sin3-Rpd3 Chromatin Remodeling Complexes in Transcriptional Repression

2001 • 210 citations

Role for ADA/GCN5 Products in Antagonizing Chromatin-Mediated Transcriptional Repression

1997 • 203 citations

Nucleosome mobilization and positioning by ISWI-containing chromatin-remodeling factors

2001 • 202 citations

Gcn4 Activator Targets Gcn5 Histone Acetyltransferase to Specific Promoters Independently of Transcription

2000 • 201 citations

Nucleosome Core Displacement in Vitro via a Metastable Transcription Factor-Nucleosome Complex

1992 • 198 citations

The Gcn5 bromodomain co-ordinates nucleosome remodelling

2000 • 194 citations

dMi-2 and ISWI chromatin remodelling factors have distinct nucleosome binding and mobilization properties

2000 • 186 citations

ATP-Driven Chromatin Remodeling Activity and Histone Acetyltransferases Act Sequentially during Transactivation by RAR/RXR In Vitro

2000 • 184 citations

Activation Domain-Specific and General Transcription Stimulation by Native Histone Acetyltransferase Complexes

1999 • 155 citations

Effects of histone acetylation on the equilibrium accessibility of nucleosomal DNA target sites 1 1Edited by R. Ebright

2001 • 152 citations

Transcription-induced nucleosome ‘splitting’: an underlying structure for DNase I sensitive chromatin.

1991 • 142 citations

The Yeast SWI-SNF Complex Facilitates Binding of a Transcriptional Activator to Nucleosomal Sites In Vivo

1997 • 139 citations

ISWI Induces Nucleosome Sliding on Nicked DNA

2001 • 136 citations

Promoter targeting of chromatin-modifying complexes

2001 • 129 citations

Generation and Interconversion of Multiple Distinct Nucleosomal States as a Mechanism for Catalyzing Chromatin Fluidity

2001 • 124 citations

Transcriptional Activation Domains of Human Heat Shock Factor 1 Recruit Human SWI/SNF

2001 • 121 citations

SWI/SNF Chromatin Remodeling Requires Changes in DNA Topology

2001 • 119 citations

Functional Delineation of Three Groups of the ATP-dependent Family of Chromatin Remodeling Enzymes

2000 • 117 citations

Mi2, an auto-antigen for dermatomyositis, is an ATP-dependent nucleosome remodeling factor

2001 • 116 citations

An embarrassment of niches: the many covalent modifications of histones in transcriptional regulation

2001 • 112 citations

SWI-SNF-Mediated Nucleosome Remodeling: Role of Histone Octamer Mobility in the Persistence of the Remodeled State

2000 • 109 citations

Rb-mediated chromatin structure regulation and transcriptional repression

2001 • 107 citations

A Role for Transcriptional Repressors in Targeting the Yeast Swi/Snf Complex

1999 • 105 citations

Glucocorticoid receptor-mediated chromatin remodeling in vivo

2001 • 92 citations

Direct Imaging of Human SWI/SNF-Remodeled Mono- and Polynucleosomes by Atomic Force Microscopy Employing Carbon Nanotube Tips

2001 • 87 citations

ATP-Dependent Histone Octamer Mobilization and Histone Deacetylation Mediated by the Mi-2 Chromatin Remodeling Complex

2000 • 85 citations

Functional Differences between the Human ATP-dependent Nucleosome Remodeling Proteins BRG1 and SNF2H

2001 • 83 citations

Increasing the rate of chromatin remodeling and gene activation--a novel role for the histone acetyltransferase Gcn5

2001 • 81 citations

The Core Histone N-Terminal Domains Are Required for Multiple Rounds of Catalytic Chromatin Remodeling by the SWI/SNF and RSC Complexes

1999 • 75 citations

Stable Remodeling of Tailless Nucleosomes by the Human SWI-SNF Complex

1999 • 66 citations

Binding of TATA Binding Protein to a Naturally Positioned Nucleosome Is Facilitated by Histone Acetylation

2001 • 61 citations

ATP-dependent Nucleosome Remodeling and Histone Hyperacetylation Synergistically Facilitate Transcription of Chromatin

2001 • 55 citations

Stability of a Human SWI-SNF Remodeled Nucleosomal Array

2001 • 39 citations

hSWI/SNF Disrupts Interactions between the H2A N-Terminal Tail and Nucleosomal DNA

1999 • 32 citations