Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

Translating the Histone Code

2001 • 9,488 citations

The language of covalent histone modifications

2000 • 8,260 citations

Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome

1999 • 1,774 citations

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

2001 • 1,480 citations

Histone acetylation and an epigenetic code

2000 • 1,164 citations

ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION

1998 • 1,124 citations

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

1987 • 731 citations

Rad6-Dependent Ubiquitination of Histone H2B in Yeast

2000 • 662 citations

Chromatin

1989 • 606 citations

Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae

2001 • 590 citations

The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4

2001 • 586 citations

Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena

1999 • 480 citations

Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage.

1993 • 463 citations

Global histone acetylation and deacetylation in yeast

2000 • 457 citations

Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions

2001 • 398 citations

Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast.

1997 • 376 citations

DNA REPAIR GENES AND PROTEINS OF SACCHAROMYCES CEREVISIAE

1993 • 301 citations

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

1991 • 266 citations

A Genetic Screen for Ribosomal DNA Silencing Defects Identifies Multiple DNA Replication and Chromatin-Modulating Factors

1999 • 227 citations

Evidence that Set1, a Factor Required for Methylation of Histone H3, Regulates rDNA Silencing in S. cerevisiae by a Sir2-Independent Mechanism

2002 • 207 citations

The RAD6 protein of Saccharomyces cerevisiae polyubiquitinates histones, and its acidic domain mediates this activity.

1988 • 196 citations

Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions.

1990 • 155 citations

The Ubiquitin-Conjugating Enzyme Rad6 (Ubc2) Is Required for Silencing in Saccharomyces cerevisiae

1997 • 126 citations

A General Requirement for the Sin3-Rpd3 Histone Deacetylase Complex in Regulating Silencing in Saccharomyces cerevisiae

1999 • 112 citations

Domains Required for Dimerization of Yeast Rad6 Ubiquitin-Conjugating Enzyme and Rad18 DNA Binding Protein

1997 • 108 citations

N-recognin/Ubc2 interactions in the N-end rule pathway

1993 • 88 citations

The extremely conserved amino terminus of RAD6 ubiquitin-conjugating enzyme is essential for amino-end rule-dependent protein degradation.

1993 • 82 citations

The N-end Rule

1995 • 56 citations

Above and within the genome: epigenetics past and present.

2001 • 50 citations

The E2 Ubiquitin Conjugase Rad6 Is Required for the ArgR/Mcm1 Repression ofARG1Transcription

2002 • 47 citations

Growth Substances in Plants

1935 • 30 citations