Genetic and molecular analyses of motoneuron development

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1996 • 3,041 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

1996 • 1,253 citations

Neuropilin Is a Semaphorin III Receptor

1997 • 1,166 citations

Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III

1997 • 1,131 citations

Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling

1997 • 1,019 citations

Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes

1994 • 1,005 citations

Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor

1996 • 982 citations

Vertebrate genome evolution and the zebrafish gene map

1998 • 823 citations

Requirement for LIM Homeobox Gene Isl1 in Motor Neuron Generation Reveals a Motor Neuron– Dependent Step in Interneuron Differentiation

1996 • 774 citations

Diversity and Pattern in the Developing Spinal Cord

1996 • 714 citations

Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta

1995 • 669 citations

Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis

1997 • 561 citations

Patterning activities of vertebrate hedgehog proteins in the developing eye and brain

1995 • 557 citations

cAMP-Dependent Growth Cone Guidance by Netrin-1

1997 • 550 citations

The Embryonic Central Nervous System Lineages ofDrosophila melanogaster

1996 • 523 citations

Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell-cell interactions

1996 • 519 citations

Mechanisms and Molecules that Control Growth Cone Guidance

1996 • 515 citations

Eph Family Transmembrane Ligands Can Mediate Repulsive Guidance of Trunk Neural Crest Migration and Motor Axon Outgrowth

1997 • 477 citations

Genetic Analysis of Netrin Genes in Drosophila: Netrins Guide CNS Commissural Axons and Peripheral Motor Axons

1996 • 459 citations

frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance

1996 • 456 citations

The Embryonic Central Nervous System Lineages ofDrosophila melanogaster

1997 • 415 citations

Genes that control neuromuscular specificity in Drosophila

1993 • 413 citations

Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1

1996 • 410 citations

Hepatocyte Growth Factor/Scatter Factor Is an Axonal Chemoattractant and a Neurotrophic Factor for Spinal Motor Neurons

1996 • 403 citations

Motor Neuron–Derived Retinoid Signaling Specifies the Subtype Identity of Spinal Motor Neurons

1998 • 383 citations

Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish

1998 • 355 citations

Specification of Motor Neuron Identity by the MNR2 Homeodomain Protein

1998 • 340 citations

The Drosophila Neuromuscular Junction: A Model System for Studying Synaptic Development and Function

1996 • 338 citations

The Transmembrane Tyrosine Phosphatase DLAR Controls Motor Axon Guidance in Drosophila

1996 • 331 citations

Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell-cell interactions

1996 • 319 citations

The Origin, Location, and Projections of the Embryonic Abdominal Motorneurons ofDrosophila

1997 • 296 citations

Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish

1995 • 290 citations

The Drosophila islet Gene Governs Axon Pathfinding and Neurotransmitter Identity

1997 • 283 citations

Receptor Tyrosine Phosphatases Are Required for Motor Axon Guidance in the Drosophila Embryo

1996 • 273 citations

Multiple delta genes and lateral inhibition in zebrafish primary neurogenesis

1998 • 268 citations

Neurogenic genes and vertebrate neurogenesis

1996 • 268 citations

Genetic Analysis of the Mechanisms Controlling Target Selection: Complementary and Combinatorial Functions of Netrins, Semaphorins, and IgCAMs

1998 • 256 citations

Versican is selectively expressed in embryonic tissues that act as barriers to neural crest cell migration and axon outgrowth

1995 • 251 citations

Motor Axon Subpopulations Respond Differentially to the Chemorepellents Netrin-1 and Semaphorin D

1997 • 237 citations

Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity

1998 • 219 citations

Pax-6 is involved in the specification of hindbrain motor neuron subtype

1997 • 217 citations

Zebrafish Make a Big Splash

1996 • 206 citations

The control of rostrocaudal pattern in the developing spinal cord: specification of motor neuron subtype identity is initiated by signals from paraxial mesoderm

1998 • 179 citations

Genetic Analysis of the Mechanisms Controlling Target Selection: Target-Derived Fasciclin II Regulates the Pattern of Synapse Formation

1997 • 176 citations

The Transmembrane Semaphorin Sema I Is Required in Drosophila for Embryonic Motor and CNS Axon Guidance

1998 • 176 citations

Inhibition of motor axon growth by T-cadherin substrata

1996 • 169 citations

Regulation of neuronal specification in the zebrafish spinal cord by Delta function

1998 • 157 citations

Dorsoventral patterning in the Drosophila central nervous system: the vnd homeobox gene specifies ventral column identity

1998 • 155 citations

Differential Expression of LIM Homeobox Genes among Motor Neuron Subpopulations in the Developing Chick Brain Stem

1996 • 153 citations

Development of branchiomotor neurons in zebrafish

1997 • 147 citations

Competition and cooperation among receptor tyrosine phosphatases control motoneuron growth cone guidance in Drosophila

1997 • 147 citations

Drosophila Rac1 controls motor axon guidance

1998 • 144 citations

The role of the msh homeobox gene during Drosophila neurogenesis: implication for the dorsoventral specification of the neuroectoderm

1997 • 140 citations

Genetic mechanisms of early neurogenesis inDrosophila melanogaster

1995 • 137 citations

The Drosophila beaten path Gene Encodes a Novel Secreted Protein That Regulates Defasciculation at Motor Axon Choice Points

1996 • 134 citations

msh may play a conserved role in dorsoventral patterning of the neuroectoderm and mesoderm

1996 • 129 citations

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase β

1998 • 126 citations

Increased apoptosis of motoneurons and altered somatotopic maps in the brachial spinal cord of Hoxc-8-deficient mice

1998 • 126 citations

Neurogenesis in the insect central nervous system

1996 • 115 citations

Pathfinding by Identified Zebrafish Motoneurons in the Absence of Muscle Pioneers

1997 • 109 citations

Molecular Heterogeneity among Primary Motoneurons and within Myotomes Revealed by the Differential mRNA Expression of Novel Islet-1 Homologs in Embryonic Zebrafish

1995 • 109 citations

Altered Forebrain and Hindbrain Development in Mice Mutant for theGsh-2Homeobox Gene

1997 • 105 citations

Gsh‐1: A novel murine homeobox gene expressed in the central nervous system

1995 • 105 citations

The receptor tyrosine kinase, Cek8, is transiently expressed on subtypes of motoneurons in the spinal cord during development

1996 • 105 citations

T-cadherin expression delineates specific regions of the developing motor axon-hindlimb projection pathway

1994 • 104 citations

Formation and specification of ventral neuroblasts is controlled by vnd in Drosophila neurogenesis

1998 • 103 citations

Rhombomere-specific origin of the contralateral vestibulo-acoustic efferent neurons and their migration across the embryonic midline

1993 • 101 citations

Disruption ofMsx-1 andMsx-2 reveals roles for these genes in craniofacial, eye, and axial development

1997 • 101 citations

Axon Tracts Correlate withNetrin-1aExpression in the Zebrafish Embryo

1997 • 95 citations

Expression and regulation of a netrin homologue in the zebrafish embryo

1997 • 95 citations

Toll, a muscle cell surface molecule, locally inhibits synaptic initiation of the RP3 motoneuron growth cone in Drosophila

1997 • 94 citations

Mutations in theDrosophila neuroglian cell adhesion molecule affect motor neuron pathfinding and peripheral nervous system patterning

1997 • 91 citations

Growth cones and the cues that repel them

1996 • 87 citations

Temporal Separation in the Specification of Primary and Secondary Motoneurons in Zebrafish

1997 • 87 citations

Expression of theTyro4/Mek4/Cek4Gene Specifically Marks a Subset of Embryonic Motor Neurons and Their Muscle Targets

1996 • 84 citations

Neuronal diversification: development of motor neuron subtypes

1998 • 84 citations

The Eph Kinase Ligand AL-1 Is Expressed by Rostral Muscles and Inhibits Outgrowth from Caudal Neurons

1996 • 84 citations

Regulation of vertebrate neural cell fate by transcription factors

1996 • 81 citations

Expression Pattern of Collagen IX and Potential Role in the Segmentation of the Peripheral Nervous System

1996 • 76 citations

The role ofPax-6in eye and nasal development

1997 • 67 citations

Neural Development: A ‘LIM code’ for motor neurons?

1995 • 59 citations

Vitronectin is expressed in the ventral region of the neural tube and promotes the differentiation of motor neurons

1997 • 57 citations

Development of Motoneuronal Phenotype

1994 • 57 citations

Homophilic synaptic target recognition mediated by immunoglobulin-like cell adhesion molecule Fasciclin III

1997 • 56 citations

Neurotrophin 3 stimulates the differentiation of motoneurons from avian neural tube progenitor cells.

1994 • 54 citations

Early pressure screens.

1999 • 48 citations

Guidance of developing axons by netrin-1 and its receptors.

1997 • 42 citations

Coordination of early neural tube development by BDNF/trkB

1997 • 42 citations

TWH Regulates the Development of Subsets of Spinal Cord Neurons

1997 • 41 citations

The inhibitory effect on neurite outgrowth of motoneurons exerted by the ligands ELF-1 and RAGS

1997 • 40 citations

Connectin Mediates Adhesion in Drosophila

1997 • 35 citations

Notochord alters the permissiveness of myotome for pathfinding by an identified motoneuron in embryonic zebrafish

1997 • 34 citations

The many faces of fasciclin II: Genetic analysis reveals multiple roles for a cell adhesion molecule during the generation of neuronal specificity.

1997 • 27 citations

Regional specification of motoneurons along the anterior-posterior axis is independent of the notochord

1996 • 26 citations

Polarity, proliferation and the hedgehog pathway

1996 • 26 citations

Segmentation and the development of the vertebrate nervous system.

1990 • 24 citations

Pathway selection by ectopic motoneurons in embryonic zebrafish

1992 • 16 citations

Virally Mediated Misexpression of Hoxc-6 in the Cervical Mesoderm Results in Spinal Nerve Truncations

1996 • 15 citations

Segmentation and the development of the nervous system

1990 • 13 citations

Commitment of Motoneuron Progenitors of Chick Embryo along the Anterior-Posterior Axis

1997 • 11 citations