Regulation of vertebrate neural cell fate by transcription factors

Hox genes in vertebrate development

1994 • 2,057 citations

Inducible Gene Targeting in Mice

1995 • 1,897 citations

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

1995 • 1,060 citations

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate.

1994 • 1,032 citations

Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein

1995 • 1,028 citations

Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

1993 • 1,019 citations

Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes

1994 • 1,005 citations

HNF-3β is essential for node and notochord formation in mouse development

1994 • 985 citations

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1994 • 807 citations

Requirement for LIml in head-organizer function

1995 • 801 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

1994 • 786 citations

Induction of epidermis and inhibition of neural fate by Bmp-4

1995 • 782 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out.

1994 • 686 citations

Early Stages of Motor Neuron Differentiation Revealed by Expression of Homeobox Gene Islet-1

1992 • 638 citations

The midbrain-hindbrain phenotype of Wnt-1−Wnt-1− mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum

1992 • 579 citations

Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt- 3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries

1993 • 570 citations

Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres

1995 • 569 citations

Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors

1990 • 533 citations

Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum

1994 • 509 citations

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

1993 • 452 citations

Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells.

1991 • 441 citations

Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system

1993 • 417 citations

Subtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 Homeobox

1991 • 416 citations

Rescue of the En-1 Mutant Phenotype by Replacement of En-1 with En-2

1995 • 402 citations

Segmental organization of embryonic diencephalon

1993 • 395 citations

The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor

1994 • 391 citations

The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system

1990 • 383 citations

A Mammalian Helix-Loop-Helix Factor Structurally Related to the Product of Drosophila Proneural Gene atonal Is a Positive Transcriptional Regulator Expressed in the Developing Nervous System

1995 • 361 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 356 citations

Evolution and role of Pax genes

1993 • 337 citations

Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord

1993 • 326 citations

Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum

1991 • 325 citations

Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants

1994 • 310 citations

Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations

1992 • 307 citations

The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm

1993 • 292 citations

The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype

1993 • 290 citations

HNF-3β as a regulator of floor plate development

1994 • 287 citations

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.

1995 • 274 citations

goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development

1995 • 263 citations

Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein

1994 • 262 citations

Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death

1995 • 262 citations

The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse.

1995 • 259 citations

The cellular function of MASH1 in autonomic neurogenesis

1995 • 241 citations

Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene.

1993 • 234 citations

Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain

1994 • 213 citations

Expression of winged helix genes, BF‐1 and BF‐2, define adjacent domains within the developing forebrain and retina

1994 • 208 citations

Pax: Gene regulators in the developing nervous system

1993 • 195 citations

Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous

1995 • 189 citations

Anterior mesendoderm induces mouse Engrailed genes in explant cultures

1993 • 164 citations

GENETIC CONTROL OF CELL FATE SPECIFICATION IN DROSOPHILA PERIPHERAL NERVOUS SYSTEM

1994 • 155 citations

Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons

1995 • 152 citations

Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1

1995 • 151 citations

The role of the notochord and floor plate in inductive interactions

1995 • 139 citations

1 Homeobox Gene Expression during Development of the Vertebrate Brain

1994 • 131 citations

A chicken achaete-scute homolog (CASH-1) is expressed in a temporally and spatially discrete manner in the developing nervous system

1994 • 130 citations

A transcription factor controlling development of peripheral sense organs in C. elegans

1995 • 129 citations

Zebrafish pax[b] is involved in the formation of the midbrain–hindbrain boundary

1992 • 127 citations

XASH-3, a novel Xenopus achaete-scute homolog, provides an early marker of planar neural induction and position along the mediolateral axis of the neural plate

1993 • 125 citations

Of Flies and Fishes

1994 • 123 citations

Mechanisms of early neurogenesis in Drosophila melanogaster

1993 • 120 citations

XASH genes promote neurogenesis in Xenopus embryos

1994 • 118 citations

Expression of the unc-4 homeoprotein in Caenorhabditis elegans motor neurons specifies presynaptic input

1995 • 114 citations

Pattern formation in the vertebrate neural plate

1994 • 114 citations

The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head.

1993 • 110 citations

MATH‐2, a Mammalian Helix‐Loop‐Helix Factor Structurally Related to the Product ofDrosophilaProneural Geneatonal, is Specifically Expressed in the Nervous System

1995 • 108 citations

A Method for Generating Transgenic Frog Embryos

2008 • 106 citations

A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes

1995 • 103 citations

Specification of neuroblast identity in the Drosophila embryonic central nervous system by gooseberry-distal

1995 • 94 citations

Determination events in the nervous system of the vertebrate embryo

1995 • 93 citations

XASH1, a Xenopus homolog of achaete-scute: a proneural gene in anterior regions of the vertebrate CNS

1993 • 92 citations

Tissue interactions affecting the migration and differentiation of neural crest cells in the chick embryo

1991 • 90 citations

A homeobox gene involved in node, notochord and neural plate formation of chick embryos

1995 • 85 citations

Ectopic expression of either the Drosophila gooseberry-distal or proximal gene causes alterations of cell fate in the epidermis and central nervous system

1994 • 60 citations

Midline cells and the organization of the vertebrate neuraxis

1993 • 43 citations

Early CNS development: Distal-less related genes and forebrain development

1994 • 39 citations

Roads to neuralness: Embryonic neural induction as derepression of a default state

1994 • 36 citations

Identification of mammalian cell clones exhibiting highly regulated expression from inducible promoters

1995 • 30 citations