Gsh‐1: A novel murine homeobox gene expressed in the central nervous system

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 2,165 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

1994 • 1,271 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization

1993 • 777 citations

The engrailed locus of drosophila: Structural analysis of an embryonic transcript

1985 • 735 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.

1993 • 617 citations

Roles of Pax-genes in developing and adult brain as suggested by expression patterns

1994 • 582 citations

Pronounced Reduction of Total Neuron Number in Mediodorsal Thalamic Nucleus and Nucleus Accumbens in Schizophrenics

1990 • 558 citations

Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6

1992 • 537 citations

Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum

1994 • 509 citations

G protein-coupled mechanisms and nervous signaling

1992 • 474 citations

Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs

1993 • 454 citations

Subtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 Homeobox

1991 • 416 citations

A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.

1989 • 399 citations

Isolation, structure, and expression of even-skipped: A second pair-rule gene of Drosophila containing a homeo box

1986 • 380 citations

Cooperative dimerization of paired class homeo domains on DNA.

1993 • 380 citations

The DNA binding specificity of ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein

1994 • 378 citations

Gastrulation in the mouse: The role of the homeobox gene goosecoid

1992 • 378 citations

Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.

1989 • 373 citations

Variations of cervical vertebrate after expression of a Hox-1.1 transgene in mice

1990 • 371 citations

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1992 • 364 citations

What determines the specificity of action of Drosophila homeodomain proteins?

1990 • 357 citations

Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments

1993 • 352 citations

Expression of homeo box genes during mouse development: a review.

1988 • 331 citations

En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis.

1987 • 330 citations

Mesodermal Control of Neural Cell Identity: Floor Plate Induction by the Notochord

1990 • 300 citations

The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system.

1990 • 299 citations

Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila

1988 • 289 citations

Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene

1992 • 289 citations

Dorsal thalamic lesion in a noted case of human memory dysfunction

1979 • 281 citations

Functional domains of the Drosophila Engrailed protein.

1993 • 280 citations

A mouse gene related to Distal-less shows a restricted expression in the developing forebrain

1991 • 273 citations

extradenticle Raises the DNA binding specificity of homeotic selector gene products

1994 • 269 citations

Homeotic transformations and limb defects in Hox A11 mutant mice.

1993 • 260 citations

Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11

1994 • 253 citations

Ectopic expression of Hoxb-8 causes duplication of the ZPA in the forelimb and homeotic transformation of axial structures

1994 • 245 citations

Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain.

1993 • 241 citations

Transgenic mice overexpressing the mouse homoeobox-containing gene Hox-1.4 exhibit abnormal gut development

1989 • 211 citations

Isolation and characterization of a novel cDNA clone encoding a homeodomain that is developmentally regulated in the ventral forebrain

1991 • 209 citations

The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos

1993 • 209 citations

A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine.

1988 • 202 citations

Position-dependent expression of two related homeobox genes in developing vertebrate limbs

1991 • 181 citations

Hox Genes and Regionalization of the Nervous System

1994 • 172 citations

Homeotic transformations in the mouse induced by overexpression of a human Hox3.3 transgene

1992 • 160 citations

Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development

1992 • 158 citations

Functional neuroanatomy and neuropathology of the human hypothalamus

1993 • 149 citations

Analysis of mouse Evx genes: Evx-1 displays graded expression in the primitive streak

1992 • 141 citations

The Hox-1.3 homeo box protein is a sequence-specific DNA-binding phosphoprotein.

1989 • 139 citations

Early Evolutionary Origin of Major Homeodomain Sequence Classes

1993 • 131 citations

Spatially restricted expression of a member of a new family of murine Distal-less homeobox genes in the developing forebrain.

1991 • 128 citations

Altering the boundaries of Hox3.1 expression: Evidence for antipodal gene regulation

1992 • 125 citations

Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival.

1994 • 121 citations

Elevated Thalamic Dopamine: Possible Link to Sensory Dysfunctions in Schizophrenia

1987 • 114 citations

Two homeo domain proteins bind with similar specificity to a wide range of DNA sites in Drosophila embryos.

1994 • 112 citations

The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development.

1991 • 111 citations

Gsh-2, a murine homeobox gene expressed in the developing brain

1995 • 90 citations

Expression pattern of a murine homeobox gene, Dbx, displays extreme spatial restriction in embryonic forebrain and spinal cord.

1992 • 84 citations

Chemical synthesis of a peptide fragment of thymopoietin II that induces selective T cell differentiation

1975 • 83 citations

Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster.

1994 • 77 citations

Distal-less is a downstream gene of Deformed required for ventral maxillary identity

1993 • 77 citations

Ectopic expression of Hox-2.3 induces craniofacial and skeletal malformations in transgenic mice

1992 • 62 citations

Identification of 10 murine homeobox genes.

1991 • 60 citations

A Xenopus homeobox gene defines dorsal-ventral domains in the developing brain

1993 • 50 citations

Dominant mutation of the murine Hox‐2.2 gene results in developmental abnormalities

1992 • 49 citations

Functional differences between HOX proteins conferred by two residues in the homeodomain N-terminal arm.

1994 • 43 citations

Isolation and characterization of a library of cDNA clones that are preferentially expressed in the embryonic telencephalon

1992 • 42 citations

Early development of the human thalamus: Golgi and Nissl study

1991 • 40 citations

Isolation of polyadenylated RNA from cultured cells and intact tissues.

1993 • 37 citations

Functional Differences between HOX Proteins Conferred by Two Residues in the Homeodomain N-Terminal Arm

1994 • 18 citations