Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/Bid Pathway

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

1998 • 4,383 citations

Molecular characterization of mitochondrial apoptosis-inducing factor

1999 • 4,031 citations

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

1998 • 3,603 citations

Apoptosis, oncosis, and necrosis. An overview of cell death.

1995 • 3,325 citations

THE MITOCHONDRIAL DEATH/LIFE REGULATOR IN APOPTOSIS AND NECROSIS

1998 • 1,982 citations

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

1997 • 1,851 citations

Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis

1999 • 1,255 citations

Bid Induces the Oligomerization and Insertion of Bax into the Outer Mitochondrial Membrane

2000 • 1,150 citations

Checkpoints of dueling dimers foil death wishes

1994 • 806 citations

Bax-induced Caspase Activation and Apoptosis via Cytochromec Release from Mitochondria Is Inhibitable by Bcl-xL

1999 • 717 citations

Bcl-X _L interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1998 • 534 citations

Caspase-independent programmed cell death with necrotic morphology

1999 • 378 citations

Granzyme B–Mediated Cytochrome C Release Is Regulated by the Bcl-2 Family Members Bid and Bax

2000 • 306 citations

Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways

2000 • 305 citations

Apoptotic and necrotic cell death induced by death domain receptors

2001 • 281 citations

Oxygen Toxicity in Mouse Lung: Pathways to Cell Death

1998 • 262 citations

Cellular Oxygen Toxicity

1996 • 260 citations

Interleukin-6–Induced Protection in Hyperoxic Acute Lung Injury

2000 • 227 citations

Apoptosis and necrosis in toxicology: A continuum or distinct modes of cell death?

1997 • 213 citations

AMID, an Apoptosis-inducing Factor-homologous Mitochondrion-associated Protein, Induces Caspase-independent Apoptosis

2002 • 211 citations

Molecules in focus Bax. The pro-apoptotic Bcl-2 family member, Bax

1998 • 164 citations

Endothelial Cell Apoptosis in Lipopolysaccharide–Induced Lung Injury in Mice

1998 • 137 citations

MAP kinases contribute to IL-8 secretion by intestinal epithelial cells via a posttranscriptional mechanism

2002 • 129 citations

Activated satellite cells fail to restore myonuclear number in spinal cord transected and exercised rats

1999 • 126 citations

Signal Transduction Pathways in Hyperoxia-Induced Lung Cell Death

2000 • 125 citations

Bcl-2 Inhibits a Fas-induced Conformational Change in the Bax N Terminus and Bax Mitochondrial Translocation

2000 • 121 citations

The Cyclin-Dependent Kinase Inhibitor p21 Protects the Lung from Oxidative Stress

2001 • 111 citations

Exposure to Hyperoxia Induces p53 Expression in Mouse Lung Epithelium

1998 • 110 citations

Apoptosis in Neonatal Murine Lung Exposed to Hyperoxia

2001 • 110 citations

Hyperoxia‐induced Cell Death in the Lung‐the Correlation of Apoptosis, Necrosis, and Inflammation

1999 • 108 citations

Hyperoxia-induced Apoptosis Does Not Require Mitochondrial Reactive Oxygen Species and Is Regulated by Bcl-2 Proteins

2002 • 98 citations

Bcl‐2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins

1999 • 85 citations

Accumulation of p21^Cip1/WAF1 during Hyperoxic Lung Injury in Mice

1998 • 64 citations

Bcl-2 Family Gene Expression during Severe Hyperoxia Induced Lung Injury

2000 • 61 citations

Induction of p21^WAF/CIP1 during Hyperoxia

1998 • 59 citations

Hyperoxia Inhibits Oxidant-induced Apoptosis in Lung Epithelial Cells

2001 • 58 citations

Lung Growth and Development

2015 • 58 citations

Liver cell death: patterns and mechanisms.

1994 • 54 citations

Protection against pulmonary oxygen toxicity by interleukin-1 and tumor necrosis factor: Role of antioxidant enzymes and effect of cyclooxygenase inhibitors

1989 • 43 citations

Ablation of tumor necrosis factor receptor type I (p55) alters oxygen-induced lung injury

2000 • 32 citations

Pathways to Cell Death in Hyperoxia

1999 • 28 citations