The spindle checkpoint

Cell Cycle Control and Cancer

1994 • 2,575 citations

Cohesins: Chromosomal Proteins that Prevent Premature Separation of Sister Chromatids

1997 • 1,466 citations

How Proteolysis Drives the Cell Cycle

1996 • 1,277 citations

Feedback control of mitosis in budding yeast

1991 • 1,167 citations

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

1991 • 1,125 citations

A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae

1997 • 829 citations

Association of Spindle Assembly Checkpoint Component XMAD2 with Unattached Kinetochores

1996 • 785 citations

Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p.

1996 • 777 citations

How Cells Get the Right Chromosomes

1997 • 625 citations

Identification of a Human Mitotic Checkpoint Gene: hsMAD2

1996 • 609 citations

Kinetochore Localization of Murine Bub1 Is Required for Normal Mitotic Timing and Checkpoint Response to Spindle Damage

1997 • 543 citations

Yeast Hct1 Is a Regulator of Clb2 Cyclin Proteolysis

1997 • 479 citations

Cut2 proteolysis required for sister-chromatid separation in fission yeast

1996 • 451 citations

The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint.

1996 • 422 citations

A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

1994 • 402 citations

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a ‘reductional’ anaphase in the budding yeast Saccharomyces cerevisiae.

1995 • 402 citations

The spindle assembly checkpoint

1996 • 364 citations

Mitosis in Living Budding Yeast: Anaphase A But No Metaphase Plate

1997 • 362 citations

Activation of the Budding Yeast Spindle Assembly Checkpoint Without Mitotic Spindle Disruption

1996 • 341 citations

APC-Mediated Proteolysis of Ase1 and the Morphogenesis of the Mitotic Spindle

1997 • 243 citations

Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast.

1995 • 235 citations

The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.

1994 • 231 citations

Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways.

1997 • 199 citations

The S. pombe cdc16 gene is required both for maintenance of p34cdc2 kinase activity and regulation of septum formation: a link between mitosis and cytokinesis?

1993 • 152 citations

'Anaphase' and cytokinesis in the absence of chromosomes

1996 • 111 citations

MAP Kinase Is Required for the Spindle Assembly Checkpoint but Is Dispensable for the Normal M Phase Entry and Exit in Xenopus Egg Cell Cycle Extracts

1997 • 102 citations

A Role for Mitogen-activated Protein Kinase in the Spindle Assembly Checkpoint in XTC Cells

1997 • 100 citations

The fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised.

1996 • 94 citations

Feedback control of the metaphase-anaphase transition in sea urchin zygotes: role of maloriented chromosomes.

1994 • 54 citations

Segregation of Unreplicated Chromosomes in Saccharomyces cerevisiae Reveals a Novel G₁/M-Phase Checkpoint

1995 • 51 citations

Differential Requirements for DNA Replication in the Activation of Mitotic Checkpoints in Saccharomyces cerevisiae

1997 • 21 citations