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2004 • 7,048 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 • 1,499 citations

Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment

1999 • 1,384 citations

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1997 • 1,241 citations

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1999 • 736 citations

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

1999 • 701 citations

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1996 • 602 citations

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2002 • 579 citations

Protein Nitration in Parkinsonʼs Disease

1998 • 551 citations

γ-Tocopherol traps mutagenic electrophiles such as NO _x and complements α-tocopherol: Physiological implications

1997 • 533 citations

Proteomic identification of nitrated proteins in Alzheimer's disease brain

2003 • 533 citations

Unlocking the code of 14-3-3

2004 • 459 citations

Ribosome Dysfunction Is an Early Event in Alzheimer's Disease

2005 • 395 citations

Chapter 7 Protein Oxidation Processes in Aging Brain

1997 • 389 citations

Mild cognitive impairment: transition between aging and Alzheimer's disease.

2000 • 376 citations

Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer's disease

2006 • 369 citations

Roles of fascin in cell adhesion and motility

2004 • 360 citations

4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes

1997 • 355 citations

Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach

2005 • 351 citations

Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: An approach to understand pathological and biochemical alterations in AD

2005 • 322 citations

Carbon Dioxide Enhancement of Peroxynitrite-Mediated Protein Tyrosine Nitration

1996 • 302 citations

Roles of fascin in human carcinoma motility and signaling: Prospects for a novel biomarker?

2005 • 270 citations

DNA strand breakage and activation of poly-ADP ribosyltransferase: A cytotoxic pathway triggered by peroxynitrite

1996 • 257 citations

Fascin, an Actin-bundling Protein, Induces Membrane Protrusions and Increases Cell Motility of Epithelial Cells

1998 • 256 citations

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1991 • 255 citations

Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis

2005 • 246 citations

Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment

2006 • 239 citations

Glucose regulation and cognitive functions: relation to Alzheimer's disease and diabetes

1996 • 238 citations

Tyrosine Modifications and Inactivation of Active Site Manganese Superoxide Dismutase Mutant (Y34F) by Peroxynitrite

1999 • 230 citations

Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: Implications for the role of nitration in the progression of Alzheimer's disease

2007 • 219 citations

14-3-3ζ Is an Effector of Tau Protein Phosphorylation

2000 • 215 citations

GAPDH as a sensor of NO stress

2006 • 212 citations

A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution

1996 • 211 citations

Neurofibrillary tangles of Alzheimer's disease brains contain 14-3-3 proteins

1996 • 185 citations

Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: Structures and mechanisms of product formation

2005 • 180 citations

Glyceraldehyde-3-Phosphate Dehydrogenase Inactivation by Peroxynitrite

1998 • 179 citations

Proteomic Analysis of Protein Expression and Oxidative Modification in R6/2 Transgenic Mice

2005 • 178 citations

The mitochondrial DNA polymerase as a target of oxidative damage

2002 • 176 citations

14-3-3 Connects Glycogen Synthase Kinase-3β to Tau within a Brain Microtubule-associated Tau Phosphorylation Complex

2003 • 176 citations

Collapsin Response Mediator Protein-2 Is Associated with Neurofibrillary Tangles in Alzheimer's Disease

1998 • 172 citations

Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice—a model of familial Parkinson's disease

2005 • 167 citations

Direct Evidence for the Formation of a Complex between 1-Cysteine Peroxiredoxin and Glutathione S-Transferase π with Activity Changes in Both Enzymes

2005 • 167 citations

Causes and Consequences of Disturbances of Cerebral Glucose Metabolism in Sporadic Alzheimer Disease: Therapeutic Implications

2004 • 166 citations

Oxidation of active center cysteine of bovine 1-Cys peroxiredoxin to the cysteine sulfenic acid form by peroxide and peroxynitrite

2001 • 165 citations

Metal‐Catalyzed Disruption of Membrane Protein and Lipid Signaling in the Pathogenesis of Neurodegenerative Disorders

2004 • 165 citations

Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid β-peptide (1–42) into rat brain: Implications for Alzheimer’s disease

2005 • 164 citations

Nitration and Inactivation of Tyrosine Hydroxylase by Peroxynitrite

2001 • 164 citations

Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain

2004 • 155 citations

Mild cognitive impairment (MCI) represents early-stage Alzheimer's disease

2005 • 152 citations

Oxidatively Modified GST and MRP1 in Alzheimer?s Disease Brain: Implications for Accumulation of Reactive Lipid Peroxidation Products

2004 • 152 citations

Proteomic identification of proteins oxidized by Aβ(1–42) in synaptosomes: Implications for Alzheimer's disease

2005 • 142 citations

CSF detection of the 14-3-3 protein in unselected patients with dementia

2001 • 142 citations

β-Amyloid Mediated Nitration of Manganese Superoxide Dismutase

2006 • 138 citations

Interaction of fascin and protein kinase C : a novel intersection in cell adhesion and motility

2003 • 136 citations

Expression of the dihydropyrimidinase related protein 2 (DRP-2) in Down Syndrome and Alzheimer’s disease brain is downregulated at the mRNA and dysregulated at the protein level

1999 • 129 citations

Formation of stable microspikes containing actin and the 55 kDa actin bundling protein, fascin, is a consequence of cell adhesion to thrombospondin-1: implications for the anti-adhesive activities of thrombospondin-1

1995 • 128 citations

Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases

2000 • 126 citations

Fetal life in Down Syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure

2001 • 117 citations

Elevation of brain glutathione by γ‐glutamylcysteine ethyl ester protects against peroxynitrite‐induced oxidative stress

2002 • 108 citations

Fluoride Exposure Attenuates Expression of Streptococcus pyogenes Virulence Factors

2002 • 102 citations

Efficacy and Safety of OK-432 Sclerotherapy for Giant Cystic Hygroma in a Newborn

2000 • 94 citations

The 14-3-3 proteins: gene, gene expression, and function.

2003 • 85 citations

Phosphorylation-dependent prolyl isomerization: a novel cell cycle regulatory mechanism

2000 • 83 citations

Protection against peroxynitrite‐dependent tyrosine nitration and α₁‐antiproteinase inactivation by oxidized and reduced lipoic acid

1996 • 83 citations

p-Hydroxyphenylacetaldehyde, the Major Product of l-Tyrosine Oxidation by the Myeloperoxidase-H2O2-Chloride System of Phagocytes, Covalently Modifies ε-Amino Groups of Protein Lysine Residues

1997 • 81 citations

Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species

2002 • 81 citations

Glucose intolerance, cognitive impairment and Alzheimer’s disease

1998 • 73 citations

Langerhans Cell Histiocytosis

2002 • 70 citations

Zeta 14-3-3 protein favours the formation of human tau fibrillar polymers

2004 • 67 citations

In vivo PET imaging and postmortem studies suggest potentially reversible and irreversible stages of brain metabolic failure in Alzheimer’s disease

1999 • 67 citations

Redox Proteomics

2006 • 65 citations

Inhibition of actin polymerization by peroxynitrite modulates neutrophil functional responses

2003 • 62 citations

Peroxynitrite mediates TNF-α-induced endothelial barrier dysfunction and nitration of actin

2005 • 58 citations

Peroxynitrite affects exocytosis and SNARE complex formation and induces tyrosine nitration of synaptic proteins

2002 • 55 citations

Protective effect of D609 against amyloid-beta1–42-induced oxidative modification of neuronal proteins: Redox proteomics study

2006 • 53 citations

Reactivity of Peroxynitrite and Nitric Oxide with LDL

2005 • 32 citations

Post-meiotic expression of the mouse dihydropyrimidinase-related protein 3 (DRP-3) gene during spermiogenesis

1998 • 32 citations

Hippocampal damage and cytoskeletal disruption resulting from impaired energy metabolism

1996 • 28 citations

[What is a mild cognitive impairment?].

2005 • 11 citations

Aux frontières de l’Alzheimer

2004 • 9 citations