A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

1995 • 687 citations

Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33.

1992 • 140 citations

THE PURIFICATION AND PROPERTIES OF HYDROPYRIMIDINE HYDRASE

1957 • 129 citations

Early postmitotic neurons transiently express TOAD‐64, a neural specific protein

1995 • 112 citations

THE CATABOLISM OF C14-LABELED URACIL, DIHYDROURACIL, AND β-UREIDOPROPIONIC ACID IN RAT LIVER SLICES

1957 • 82 citations

Purification, characterization and inhibition of dihydropyrimidinase from rat liver

1994 • 74 citations

Bovine liver dihydropyrimidine amidohydrolase: Purification, properties, and characterization as a zinc metalloenzyme

1983 • 73 citations

THE CATABOLISM OF C14-LABELED URACIL, DIHYDROURACIL, AND β-UREIDOPROPIONIC ACID IN THE INTACT RAT

1957 • 61 citations

Cloning, sequencing, and expression in Escherichia coli of the D-hydantoinase gene from Pseudomonas putida and distribution of homologous genes in other microorganisms

1994 • 60 citations

Dihydropyrimidinase deficiency presenting in infancy with severe developmental delay

1993 • 52 citations

The role of dihydropyrimidinase in the metabolism of some hydantoin and succinimide drugs.

1974 • 52 citations

A Thermostable Hydantoinase ofBacillus stearothermophilusNS1122A: Cloning, Sequencing, and High Expression of the Enzyme Gene, and Some Properties of the Expressed Enzyme

1994 • 52 citations

Molecular cloning and sequencing of a cDNA encoding dihydropyrimidinase from the rat liver

1996 • 31 citations

Dihydropyrimidinuria: The First Case in Japan

1995 • 27 citations

Partial purification and characterization of dihydropyrimidinases from calf and rat liver.

1978 • 24 citations

Dihydropyrimidine amidohydrolase is a zinc metalloenzyme

1979 • 18 citations

Isolation of 115 human chromosome 8-specific expressed-sequence tags by Exon amplification

1995 • 16 citations

Role of enzymatically catalyzed 5-iodo-5,6-dihydrouracil ring hydrolysis on the dehalogenation of 5-iodouracil.

1976 • 16 citations

Isolation and Characterization of 21 Novel Expressed DNA Sequences from the Distal Region of Human Chromosome 4p

1994 • 9 citations