Recognition of distinctHLA-DQA1promoter elements by a single nuclear factor containing Jun and Fos or antigenically related proteins

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene

1990 • 522 citations

Nuclear factor of activated T cells contains Fos and Jun

1992 • 495 citations

Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex

1990 • 486 citations

Regulation of Major Histocompatibility Complex Class-II Genes: X, Y and Other Letters of the Alphabet

1990 • 470 citations

Functional antagonism between c-Jun and MyoD proteins: A direct physical association

1992 • 424 citations

Nuclear Proto-Oncogenes Fos and Jun

1990 • 392 citations

Yeast HAP1 activator binds to two upstream activation sites of different sequence

1987 • 317 citations

A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes.

1988 • 239 citations

mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element.

1990 • 237 citations

IP-1: A dominant inhibitor of Fos/Jun whose activity is modulated by phosphorylation

1991 • 212 citations

Organization of the Murine Mx Gene and Characterization of Its Interferon- and Virus-Inducible Promoter

1988 • 206 citations

Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element.

1988 • 194 citations

OBP100 binds remarkably degenerate octamer motifs through specific interactions with flanking sequences.

1988 • 184 citations

Overexpression of c-jun, junB, or junD affects cell growth differently.

1991 • 136 citations

Unregulated expression of c-Jun or c-Fos proteins but not Jun D inhibits oestrogen receptor activity in human breast cancer derived cells.

1991 • 134 citations

A regulatory element that mediates co-operation between a PEA3-AP-1 element and an AP-1 site is required for phorbol ester induction of urokinase enhancer activity in HepG2 hepatoma cells.

1992 • 126 citations

Trans-acting element(s) operating across species barriers positively regulate expression of major histocompatibility complex class II genes.

1985 • 73 citations

NF-X2 that binds to the DRA X2-box is activator protein 1. Expression cloning of c-Jun.

1990 • 57 citations

mXBP/CRE-BP2 and c-Jun Form a Complex Which Binds to the Cyclic AMP, but Not to the 12-O-Tetradecanoylphorbol-13-Acetate, Response Element

1990 • 56 citations

X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.

1990 • 41 citations

Transcriptional enhancers in the HLA-DQ subregion.

1987 • 34 citations

Fos, Jun and CREB basic-domain peptides have intrinsic DNA-binding activity enhanced by a novel stabilizing factor.

1990 • 30 citations

Regulation of MHC class 11 gene transcription

1991 • 29 citations

A single transcription factor binds to two divergent sequence elements with a common function in cardiac myosin light chain-2 promoter.

1992 • 27 citations

Transcriptional and post-transcriptional regulation of human MHC class II genes require the synthesis of short-lived proteins.

1989 • 24 citations

Transcriptional Enhancers in the HLA-DQ Subregion

1987 • 22 citations

Protein complexes bearing myc-like antigenicity recognize two distinct DNA sequences.

1992 • 22 citations

DNA polymorphisms in the 5′-flanking region of the HLA-DQA1 gene

1992 • 21 citations

The molecular biology of MHC genes

1991 • 21 citations

Effect of theAIR-1 locus on the activation of an enhancerlessHLA-DQA1 promoter

1990 • 12 citations

Mapping of functional domains in Fos and Jun proteins using epitope-specific antibodies.

1990 • 9 citations