Unregulated expression of c-Jun or c-Fos proteins but not Jun D inhibits oestrogen receptor activity in human breast cancer derived cells.

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Current protocols in molecular biology

1988 • 4,543 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

1973 • 2,431 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

Firefly Luciferase Gene: Structure and Expression in Mammalian Cells

1987 • 924 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

A gene activated by growth factors is related to the oncogene v-jun.

1988 • 771 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

Parallel Association of Fos and Jun Leucine Zippers Juxtaposes DNA Binding Domains

1989 • 607 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity.

1989 • 572 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene

1990 • 522 citations

fos-associated cellular p39 is related to nuclear transcription factor AP-1

1988 • 508 citations

Characterization of junD: a new member of the jun proto-oncogene family.

1989 • 492 citations

Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex

1990 • 486 citations

jun-D: a third member of the jun gene family.

1989 • 469 citations

Commitment and activation at pol II promoters: A tail of protein-protein interactions

1990 • 332 citations

Immobilization and purification of enzymes with staphylococcal protein A gene fusion vectors.

1985 • 331 citations

The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.

1989 • 318 citations

Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB.

1990 • 290 citations

The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation

1989 • 286 citations

Estrogen-Induced Factors of Breast Cancer Cells Partially Replace Estrogen to Promote Tumor Growth

1986 • 273 citations

Characterization of the Estrogen-Induced pS2 Protein Secreted by the Human Breast Cancer Cell Line MCF-7*

1987 • 125 citations

Wounding a fibroblast monolayer results in the rapid induction of the c-fos proto-oncogene.

1986 • 117 citations

Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts.

1988 • 103 citations

Correlation between hormone dependency and the regulation of epidermal growth factor receptor by tumor promoters in human mammary carcinoma cells.

1986 • 98 citations

Both Jun and Fos contribute to transcription activation by the heterodimer.

1990 • 81 citations

Factors affecting the sensitivity of T-47D human breast cancer cells to tamoxifen.

1984 • 81 citations

Influence of 12-O-tetradecanoylphorbol-13-acetate on proliferation and maturation of human breast carcinoma cells (MCF-7): relationship to cell cycle events.

1987 • 75 citations

Jun DNA-binding is modulated by mutations between the leucines or by direct interaction of fos with the TGACTCA sequence.

1989 • 33 citations

Xenopus vitellogenin genes.

1985 • 25 citations