Organization of the Murine Mx Gene and Characterization of Its Interferon- and Virus-Inducible Promoter

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Promoter-specific activation of RNA polymerase II transcription by Sp1

1986 • 1,054 citations

A simple method for DNA restriction site mapping

1976 • 1,025 citations

γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

1985 • 949 citations

Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries.

1985 • 818 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences

1985 • 498 citations

Mx protein: Constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus

1986 • 479 citations

Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene

1982 • 464 citations

The primary structure of rabbit β-globin mRNA as determined from cloned DNA

1977 • 428 citations

Shotgun DNA sequencing using cloned DNase I-generated fragments

1981 • 425 citations

Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element.

1987 • 398 citations

Detailed analysis of the mouse H-2Kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expression

1986 • 395 citations

Compilation and analysis of eukaryotic POL II promoter sequences

1986 • 345 citations

The Interferon Genes

1986 • 304 citations

Interferon-activated genes

1986 • 301 citations

Interferon response element of the human gene 6-16.

1988 • 292 citations

Sp1 binds to promoter sequences and activates herpes simplex virus ‘immediate-early’ gene transcription in vitro

1985 • 289 citations

Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes

1986 • 288 citations

Isolation of β-globin-related genes from a human cosmid library

1981 • 277 citations

Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H–2 gene

1986 • 252 citations

Interferon induces a unique protein in mouse cells bearing a gene for resistance to influenza virus.

1983 • 247 citations

Exon/intron organization and complete nucleotide sequence of an HLA gene.

1982 • 239 citations

Activation of the human beta-interferon gene requires an interferon-inducible factor.

1986 • 237 citations

A unique set of polypeptides is induced by γ interferon in addition to those induced in common with α and β interferons

1983 • 234 citations

Interferon-β gene regulation: Tandemly repeated sequences of a synthetic 6 bp oligomer function as a virus-inducible enhancer

1987 • 233 citations

Sendai virus contains overlapping genes expressed from a single mRNA

1983 • 231 citations

Delimitation and properties of DNA sequence: required for the regulated expression of human interferon-β gene

1985 • 216 citations

Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region.

1986 • 185 citations

A 46-nucleotide promoter segment from an IFN-α gene renders an unrelated promoter inducible by virus

1985 • 185 citations

Resistance of mice to mouse-adapted influenza A virus

1962 • 171 citations

Genetically determined, interferon-dependent resistance to influenza virus in mice.

1979 • 158 citations

Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: implications for the evolution of HLA genes.

1984 • 158 citations

Host gene influences sensitivity to interferon action selectively for influenza virus

1980 • 154 citations

Structure and expression of cloned murine IFN-α genes

1983 • 154 citations

Functional equivalents of interferon-mediated signals needed for induction of an mRNA can be generated by double-stranded RNA and growth factors.

1987 • 141 citations

Genomic characterization of a gamma-interferon-inducible gene (IP-10) and identification of an interferon-inducible hypersensitive site.

1987 • 137 citations

Interferon-responsive regulatory elements in the promoter of the human 2',5'-oligo(A) synthetase gene.

1987 • 137 citations

Structure and nucleotide sequence of the heavy chain gene of HLA-DR.

1983 • 132 citations

Cell-specific expression of the human complement protein Factor B gene: Evidence for the role of two distinct 5′-flanking elements

1987 • 128 citations

Interferons as Gene Activators

1989 • 124 citations

Interferon-induced protein Mx accumulates in nuclei of mouse cells expressing resistance to influenza viruses

1985 • 123 citations

Reversible silencing of enhancers by sequences derived from the human IFN-α promoter

1987 • 119 citations

New inducers revealed by the promoter sequence analysis of two interferon-activated human genes

1987 • 110 citations

Interferons increase transcription of a major histocompatibility class I gene via a 5' interferon consensus sequence.

1987 • 105 citations

Transcriptional activation of the mouse Mx gene by type I interferon.

1986 • 92 citations

Regulation of murine class I genes by interferons is controlled by regions located both 5' and 3' to the transcription initiation site.

1987 • 91 citations

Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene.

1986 • 85 citations

Mx-dependent resistance to influenza viruses is induced by mouse interferons α and β but not γ

1984 • 78 citations

Polyclonal and monoclonal antibodies to the interferon-inducible protein Mx of influenza virus-resistant mice.

1985 • 77 citations

Controlled transcription of a human α-interferon gene introduced into mouse L cells

1982 • 72 citations

Transport of the Murine Mx Protein into the Nucleus Is Dependent on a Basic Carboxy-Terminal Sequence

1987 • 66 citations

The 5′-flanking region of a human IFN-α gene mediates viral induction of transcription

1983 • 53 citations

Host gene influence on interferon action in adult mouse hepatocytes: Specificity for influenza virus

1980 • 32 citations

Expression of interferon dependent resistance to influenza virus in mouse embryo cells

1983 • 29 citations

In vivo competition of delta-crystallin gene expression by DNA fragments containing a GC box.

1986 • 18 citations