Vχ gene segments rearranged in chronic lymphocytic leukemia are distributed over a large portion of the Vχ locus and do not show somatic mutation

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

1984 • 644 citations

CD5+ B lymphocytes, polyreactive antibodies and the human B-cell repertoire

1989 • 461 citations

Most peripheral B cells in mice are ligand selected.

1991 • 424 citations

Evolution of human immunoglobulin kappa J region genes.

1982 • 318 citations

Differential development of progenitor activity for three B-cell lineages.

1992 • 305 citations

Stable Expression and Somatic Hypermutation of Antibody V Regions in B-Cell Developmental Pathways

1989 • 271 citations

Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia.

1989 • 239 citations

Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family‐specific oligonucleotide probes

1991 • 215 citations

Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy.

1988 • 177 citations

‘Prolymphocytoid’ Transformation of Chronic Lymphocytic Leukaemia

1979 • 176 citations

The response of human platelets to activated components of the complement system

1991 • 175 citations

Evolution of immunoglobulin V genes: Evidence indicating that recently duplicated human Vκ sequences have diverged by gene conversion

1983 • 165 citations

International Agency for Research on Cancer

2022 • 158 citations

Restricted Ig variable region gene expression among Ly-1+ B cell lymphomas.

1988 • 141 citations

Germline antibody V regions as determinants of clonal persistence and malignant growth in the B cell compartment.

1988 • 139 citations

Immunoglobulin genes of different subgroups are interdigitated within the V_Klocus

1984 • 110 citations

Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene

1985 • 109 citations

Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa type

1984 • 107 citations

High-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia.

1987 • 99 citations

Isolation and characterization of a light chain variable region gene for human rheumatoid factors.

1987 • 94 citations

The human VK locus

1988 • 90 citations

The human immunoglobulinx locus. Characterization of the duplicated O regions

1991 • 89 citations

Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. IV. The less frequently expressed VL are heterogeneous.

1991 • 75 citations

Physical map of the human immunoglobulin K locus and its implications for the mechanisms of V^K–J^Krearrangement

1987 • 72 citations

The V_ϰ gene repertoire in the human germ line

1990 • 70 citations

Human Immunoglobulin kappa light chain genes of subgroups II and III

1985 • 69 citations

Uniform high frequency expression of autoantibody-associated crossreactive idiotypes in the primary B cell follicles of human fetal spleen.

1990 • 67 citations

Epstein-Barr virus-positive Burkitt's lymphoma in a german woman during pregnancy

1980 • 64 citations

Isolation and characterization of human VkIII germ-line genes. Implications for the molecular basis of human VkIII light chain diversity.

1987 • 62 citations

Characterization of four homologous L chain variable region genes that are related to 6B6.6 idiotype positive human rheumatoid factor L chains.

1989 • 60 citations

Intraclonal diversity in the VH genes expressed by CD5- chronic lymphocytic leukemia-producing pathologic IgM rheumatoid factor.

1990 • 57 citations

Early rearrangements of genes encoding murine immunoglobulin kappa chains, unlike genes encoding heavy chains, use variable gene segments dispersed throughout the locus.

1989 • 56 citations

Linking of the human immunoglobulin V_KJ_KC_Kregions by chromosomal walking

1987 • 49 citations

The human immunoglobulin x locus. Characterization of the duplicated A regions

1992 • 49 citations

Light chains of immunoglobulins: structural-genetic correlates

1986 • 47 citations

Selective expression of a VHIV subfamily of immunoglobulin genes in human CD5+ B lymphocytes from cord blood.

1991 • 43 citations

Megabase inversions in the human genome as physiological events

1990 • 42 citations

Immunoglobulin genes of thexlight chain type from two human lymphoid cell lines are closely related

1984 • 39 citations

Aberrant recombination events in B cell lines derived from ax-deficient human

1985 • 37 citations

Two Unusual Human Immunoglobulin V_κGenes

1988 • 19 citations

Shared idiotype expression by chronic lymphocytic leukemia and B-cell lymphoma

1990 • 15 citations