Early reduction of the over-expression of CD40L, OX40 and Fas on T cells in HIV-1 infection during triple anti-retroviral therapy: possible implications for lymphocyte traffic and functional recovery

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

The Fas Death Factor

1995 • 4,070 citations

Positive Effects of Combined Antiretroviral Therapy on CD4 ⁺ T Cell Homeostasis and Function in Advanced HIV Disease

1997 • 1,812 citations

The Tumor Necrosis Factor Ligand and Receptor Families

1996 • 1,239 citations

Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation

1998 • 722 citations

Elevated CD38 Antigen Expression on CD8+ T Cells Is a Stronger Marker for the Risk of Chronic HIV Disease Progression to AIDS and Death in the Multicenter AIDS Cohort Study Than CD4+ Cell Count, Soluble Immune Activation Markers, or Combinations of HLA-DR and CD38 Expression

1997 • 551 citations

HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies

1997 • 527 citations

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production.

1996 • 516 citations

Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression.

1996 • 499 citations

CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.

1995 • 481 citations

Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals.

1995 • 438 citations

Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy

1998 • 434 citations

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory.

1994 • 431 citations

Expression and function of OX40 ligand on human dendritic cells.

1997 • 416 citations

The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells.

1996 • 303 citations

The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response.

1996 • 284 citations

Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signals.

1995 • 280 citations

HIV-1 Antigen–specific and –nonspecific B Cell Responses Are Sensitive to Combination Antiretroviral Therapy

1998 • 248 citations

Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease

1998 • 231 citations

Maximal Proliferation of Cytotoxic T Lymphocytes Requires Reverse Signaling through Fas Ligand

1998 • 217 citations

Host factors in the pathogenesis of HIV disease

1997 • 200 citations

HIV-1 Directly Kills CD4+ T Cells by a Fas-independent Mechanism

1998 • 199 citations

The CD40 pathway in allograft rejection, acceptance, and tolerance

1997 • 180 citations

CD40 Ligation on Human Cord Blood CD34+Hematopoietic Progenitors Induces Their Proliferation and Differentiation into Functional Dendritic Cells

1997 • 161 citations

Selective depletion of myelin–reactive T cells with the anti–OX–40 antibody ameliorates autoimmune encephalomyelitis

1996 • 159 citations

In vivo analysis of Fas/FasL interactions in HIV-infected patients.

1998 • 153 citations

Limited CD4+ T-cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy

1998 • 153 citations

Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis.

1996 • 144 citations

Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype.

1997 • 123 citations

HIV-induced decline in blood CD4/CD8 ratios: viral killing or altered lymphocyte trafficking?

1998 • 108 citations

CD40‐CD40 ligand interaction in autoimmune disease

1997 • 107 citations

Role of the Fas/Fas Ligand Apoptotic Pathway in Human Immunodeficiency Virus Type 1 Disease

1998 • 91 citations

Immune activation in the context of HIV infection

1998 • 88 citations

Expression of the T-Cell Activation Antigen, OX-40, Identifies Alloreactive T Cells in Acute Graft-Versus-Host Disease

1997 • 83 citations

Rapid CD4+ T-cell turnover in HIV-1 infection: A paradigm revisited

1998 • 71 citations

HIV-1 induction of CD40 on endothelial cells promotes the outgrowth of AIDS-associated B-cell lymphomas

1997 • 61 citations

Suppression of Immune Responses by CD8 Cells. I. Superantigen-Activated CD8 Cells Induce Unidirectional Fas-Mediated Apoptosis of Antigen-Activated CD4 Cells

1998 • 58 citations

Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection.

1996 • 50 citations

Kinetics of the Changes of Lymphocyte Subsets Defined by Cytokine Production at Single Cell Level During Highly Active Antiretroviral Therapy for HIV-1 Infection

1999 • 47 citations

Evidence for a Continued Requirement for CD40/CD40 Ligand (CD154) Interactions in the Progression of LP-BM5 Retrovirus-Induced Murine AIDS

1998 • 30 citations

Analysis of lymphocyte cell death and apoptosis in HIV-2-infected patients

1994 • 28 citations

Single-cell analysis of lymphokine imbalance in asymptomatic HIV-1 infection: evidence for a major alteration within the CD8+ T cell subset

1998 • 24 citations

Early increase of CD4+ CD45RA+ and CD4+ CD95− cells with conserved repertoire induced by anti-retroviral therapy in HIV-infected patients

1998 • 17 citations

Natural Resistance to Parental T‐Lymphocyte‐Induced Immunosuppression in F₁ Hybrid Mice: Implications for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 16 citations

Single-cell analysis of lymphokine imbalance in asymptomatic HIV-1 infection

1998 • 15 citations

Distinct alterations in the distribution of CD45RO+ T-cell subsets in HIV-2 compared with HIV-1 infection Ana C. Jaleco

1994 • 14 citations

Panel of Anti-gp120 Monoclonal Antibodies Reacts with Same Nuclear Proteins in Uninfected Cells as Those Recognized by Autoantibodies from Patients with Systemic Lupus Erythematosus

1994 • 10 citations